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Overview
Talk Python to Me is a weekly podcast hosted by developer and entrepreneur Michael Kennedy. Our interviews dive deep into the popular packages and software developers, data scientists, and incredible hobbyists doing amazing things with Python. If you.
News
#558: Hyper-Personal Software with Python
Every company has one. The little internal tool that Jane built back in 2021, and then Jane left. Nobody understands it, nobody will touch it. There are two unwritten rules around it: don't change it, it's working. And if you break it, you bought it. That
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#557: Security of everything at PyCon 2026
Security has always been the vegetables of software. Everyone agrees it matters, and somehow it never quite makes it onto the plate. At PyCon US this year, that changed. For the first time ever, security got its own dedicated, day-long track, one of just
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#556: Updates on Django's Async Story
For years, "Django and async" came with an asterisk. The docs themselves warned you off it. Scary performance notes, a story that felt half-finished. Well, that story just got rewritten, literally, and the person who rewrote it is here to tell you why the
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Calvin Hendryx-Parker joins Python Bytes as Co-Host
TL;DR: Calvin Hendryx-Parker is the new permanent co-host of Python Bytes , starting with episode 483 on June 9th, 2026. After almost 10 years, Brian Okken, who founded the show with me back in 2016, has decid...
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#555: Marimo Pair - A Canvas for Agent + Developers Collaboration
Coding agents have gotten really good at one kind of work. You scope a feature, edit some files, run the tests, ship it. It all happens on disk. But that is not how data work feels. You load something, you look at it, you run a cell, you watch how it resp
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