{"id":2651209,"url":"https://alion.io/job/abzena-msat-engineer","title":"MSAT Engineer","company":{"id":2138905,"name":"Abzena","domain":"abzena.com","url":"https://alion.io/company/abzena","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Lever","truth_index":{"grade":"B","score":83,"open_postings":6,"ghost_share":0,"stale_share":0.667,"repost_share":0,"time_to_fill_p50_days":22,"computed_at":"2026-10-22T06:10:10Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"middle","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Bristol, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":56000,"max_usd":102000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":4013},"experience_years_min":3,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CAPA","optional":false},{"name":"Chromatography","optional":false},{"name":"GLP","optional":false},{"name":"GMP","optional":false},{"name":"Microsoft Excel","optional":false},{"name":"Microsoft Office","optional":false}],"status":"live","first_seen_at":"2026-10-15T19:11:27Z","employer_posted_date":"2026-10-15","last_verified_at":"2026-10-22T12:57:58Z","board_verified":true,"closed_at":null,"days_open":6,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":6},"description":"The MSAT (Manufacturing Science and Technology) Department at Abzena provides technical leadership and supports technology transfer activities from Process Development to GMP Manufacturing. Additionally, MSAT is a key stakeholder for multiple secondary functions including support of Quality Systems, Process Improvements, Production Equipment Implementation, Process Automation, Data Management, etc.\nWe are seeking an experienced and highly skilled engineer with expertise in bioconjugation processes, including Antibody Drug Conjugates (ADCs) and Antibody Oligonucleotide Conjugates (AOCs), to support development-to-clinical cGMP manufacturing operations. You will serve as the MSAT technical bridge between process development and manufacturing, ensuring successful technology transfer, manufacturing readiness, and sustained process robustness for highly potent and complex biologic drug conjugates across the product lifecycle.\nResponsibilities\nProvide technical leadership for technology transfer from internal or external process development teams into cGMP manufacturing, including facility fit assessments, scale up planning, and risk assessments.\nLead transfer of bioconjugation processes into cGMP manufacturing from internal teams and external development partners.\nAuthor and revise batch records and master batch production documents to support cGMP clinical manufacturing.\nDraft and maintain cGMP documentation, including BOMs, specifications, SOPs, technology transfer documents, PFDs, and P&IDs, as required to support execution and readiness.\nLead or support process investigations, deviations, CAPAs, and root cause analysis related to cGMP manufacturing.\nChampion process safety by translating OEB controls into practical manufacturing requirements for equipment, PPE, waste, and cleaning.\nProvide in-person and real-time manufacturing production support required for project success.\nDrive continuous improvement initiatives related to process robustness, documentation, and manufacturing efficiency.\nTechnical training and knowledge management. Develop training content for new processes, new equipment, and new batch record revisions. Maintain a living knowledge package per program, including lessons learned, known failure modes, and standard responses.\nAdhere to all GLP, and cGMP requirements as well as Abzena policies, procedures, and mission while fulfilling duties, responsibilities, and tasks.\nServe as the MSAT subject matter expert (SME) for bioconjugation processes including ADCs and AOCs across early development through commercial lifecycle stages.\nQualifications\nMinimum Bachelor’s degree in scientific or engineering discipline or equivalent with 3-5 years of experience in biopharma MSAT or technical operations with a focus on ADC and/or AOC processes.\nProven track record in both development and clinical-stage support, including batch record authorship and process documentation.\nWorking knowledge of GMP operations, including manufacturing floor support, deviation resolution, and change control.\nHands-on experience with conjugation chemistries, tangential flow filtration (TFF), Protein A, ion exchange (IEX), and hydrophobic interaction chromatography (HIC).\nStrong understanding of Microsoft Office Suite including basic functions and graphing within Microsoft Excel\nFamiliarity with semi/fully automated manufacturing equipment\nProven ability to troubleshoot bioprocess operations and equipment.\nUnderstanding of relevant analytical, processing, and scale-up calculations.\nProven ability to build, modify, and utilize digital data storage, visualization, and analysis systems/tools.\nStrong interpersonal and communication skills, with the ability to interface effectively with cross-functional teams and clients","description_format":"text","description_chars":3763,"description_truncated":false,"requirements":{"experience_years_min":3,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["CRO & CDMO Services"],"lifecycle":[{"event":"open","at":"2026-10-15T21:49:01Z"}],"visa":[],"liveness":{"score":94,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.94,"p_room":1,"age_days":6,"expected_fill_days":22,"reasons":["conf:0","urgency","win:early"],"computed_at":"2026-10-22T06:10:10Z"},"pay":null,"html_url":"https://alion.io/job/abzena-msat-engineer","json_url":"https://alion.io/job/abzena-msat-engineer.json","meta":{"generated_at":"2026-10-22T14:19:04Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":13887,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-23T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2138905},"rest":"https://alion.io/mcp/rest/get_company?id=2138905"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fabzena-msat-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fabzena-msat-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fabzena-msat-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/abzena-msat-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fabzena-msat-engineer"}]}