{"id":1013403,"url":"https://alion.io/job/additiontx-research-associate-therapeutic-technologies","title":"Research Associate, Therapeutic Technologies","company":{"id":719620,"name":"Addition Therapeutics","domain":"additiontx.com","url":"https://alion.io/company/additiontx","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":78000,"max":98000,"currency":"USD","period":"year","gross":null,"usd_annual":98000},"salary_estimate":null,"experience_years_min":1,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Cell Culture","optional":false},{"name":"ELISA","optional":false},{"name":"Flow Cytometry","optional":false},{"name":"GraphPad Prism","optional":false},{"name":"Python","optional":false},{"name":"qPCR","optional":false},{"name":"Western Blot","optional":false}],"status":"live","first_seen_at":"2026-09-17T20:29:02Z","employer_posted_date":"2026-09-17","last_verified_at":"2026-11-09T11:01:44Z","board_verified":true,"closed_at":null,"days_open":52,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":52},"description":"Company\nAddition Therapeutics is at the forefront of biotechnology innovation, building the next generation of gene therapy using our proprietary PRINT™ (Precise RNA-mediated Insertion of Transgenes) platform. PRINT™ redefines genetic medicine by enabling the development of RNA-only therapeutics capable of inserting any genetic element into specific safe harbor sites within the genome. Operating from state-of-the-art labs in South San Francisco, we are a Series A-stage company advancing programs across rare and common diseases.\nThe Role\nWe are looking for a Research Associate to join our Therapeutic Technologies team. This is a hands-on, bench-focused role at the center of how we turn designs into data: you will produce the RNA reagents that drive PRINT and run the cell-based assays that tell us how well those reagents work. The ideal candidate is a versatile, hands-on experimentalist who can perform in vitro transcription (IVT) and mammalian cell culture that read out payload performance end to end - and who generates the high-quality data our programs rely on from early discovery onward. You will work side by side with our RNA sciences, protein engineering, and program teams, keeping the core experimental engine of the company running.\nAbout the Role\nThe day-to-day responsibilities of this role will include:\nProduce research-grade RNA by in vitro transcription (IVT) at routine cadence and scale - template preparation, transcription, capping and tailing, DNase treatment, and purification - and release material against defined quality specifications.\nPerform RNA quality control (concentration, purity, and integrity by spectrophotometry, fluorometry, and electrophoretic/capillary methods) and keep clear, traceable records of every lot.\nMaintain mammalian cell lines and disease-relevant models - passaging, cryopreservation, thawing, and routine health/mycoplasma monitoring - so assay-ready cells are available on schedule.\nDeliver PRINT RNA into cells by transfection, lipofection, and electroporation/nucleofection across multiple cell types.\nExecute the associated readout assays - reporter (luciferase/fluorescent) assays, ELISA for secreted proteins, qPCR/ddPCR for transgene expression and copy number, flow cytometry, and microscopy - generating accurate, reproducible data.\nAnalyze, plot, and clearly document results in the electronic lab notebook; flag anomalies and contribute to troubleshooting and protocol refinement.\nHelp keep the lab running: reagent and consumable inventory, sample and reagent tracking, and routine instrument upkeep.\nWhat We're Looking For\nRequired\nBachelor's or Master's degree in molecular biology, biochemistry, cell biology, biotechnology, or a related field, with ~1-2 years of hands-on laboratory experience (industry preferred).\nMammalian cell culture skills - sterile technique, maintenance of multiple lines, and transfection.\nHands-on molecular biology experience, including RNA handling and RNase-free technique.\nDemonstrated reliability, organization, and attention to detail - you produce reproducible data and document it clearly.\nAbility to manage multiple concurrent tasks in a fast-paced environment and to communicate results to a cross-functional team.\nPreferred\nExperience producing or QC'ing mRNA/RNA reagents (IVT, capping, tailing, integrity analysis by TapeStation/Bioanalyzer/fragment analyzer).\nExperience with standard cell-based and biochemical assays such as reporter assays, ELISA, qPCR/ddPCR, flow cytometry, or Western blot.\nExperience with fluorescence microscopy and/or flow cytometry.\nFamiliarity with gene therapy, mRNA, or other RNA-based therapeutic modalities.\nBasic data-analysis skills in R, Python, GraphPad Prism, or similar.\nWhy Addition\nYour work is the engine that directly moves our platform and programs forward.\nSmall team with real breadth: a generalist role that touches nearly every program and grows with the platform.\nWork at the intersection of cutting-edge genetic medicine and high-value disease biology.\nCompetitive salary, equity, and benefits, in a collaborative and supportive environment in South San Francisco.\nCompensation\nThe expected annual salary range for this full-time position is $78,000- $98,000, plus eligibility for bonus, benefits, and equity incentives. Actual pay will be determined based on experience, qualifications, business needs, internal equity, and alignment with market data.\nAddition Therapeutics is an equal opportunity employer. We value diverse perspectives and are committed to building an inclusive team.","description_format":"text","description_chars":4562,"description_truncated":false,"requirements":{"experience_years_min":1,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Cell & Gene Therapy"],"lifecycle":[{"event":"open","at":"2026-09-17T21:23:22Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 3","filings_12m":3,"filings_prev_12m":1,"green_card_filings_12m":0,"median_offered_wage_usd":117500,"route":null,"cap_exempt":false,"checked_at":"2026-11-09T07:32:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":45,"band":"ok","label":"Likely open","p_open":1,"p_active":0.749,"p_room":0.6,"age_days":52,"expected_fill_days":56,"reasons":["conf:4","win:late","crowd:junior"],"computed_at":"2026-11-09T06:03:00Z"},"pay":{"stated_usd_annual":98000,"is_top_pay":true},"html_url":"https://alion.io/job/additiontx-research-associate-therapeutic-technologies","json_url":"https://alion.io/job/additiontx-research-associate-therapeutic-technologies.json","meta":{"generated_at":"2026-11-09T11:19:50Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":13111,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-10T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":719620},"rest":"https://alion.io/mcp/rest/get_company?id=719620"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fadditiontx-research-associate-therapeutic-technologies"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fadditiontx-research-associate-therapeutic-technologies"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fadditiontx-research-associate-therapeutic-technologies"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/additiontx-research-associate-therapeutic-technologies\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fadditiontx-research-associate-therapeutic-technologies"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":1013403}},{"tool":"search_jobs","arguments":{"company":"additiontx.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":1013403},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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