{"id":3043724,"url":"https://alion.io/job/alector-vice-president-clinical-development","title":"Vice President, Clinical Development","company":{"id":2939952,"name":"Alector","domain":"alector.com","url":"https://alion.io/company/alector","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Lever","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"head","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":290000,"max":380000,"currency":"USD","period":"year","gross":null,"usd_annual":380000},"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-08-25T21:35:18Z","employer_posted_date":"2026-08-25","last_verified_at":"2026-11-06T07:08:19Z","board_verified":true,"closed_at":null,"days_open":72,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":72},"description":"As Vice President,Clinical Development, you will serve as Alector’s senior clinical development physician and a key clinical leader for AL137 as the program enters Phase 1 clinical trials. You will bring your medical judgment, scientific curiosity, and drug development experience to help translate an innovative program into meaningful clinical evidence.\nYou will provide medical and clinical development leadership across the program, working closely with colleagues in Clinical Operations, Translational Medicine, Regulatory, Safety, Biometrics, and other functions. As the program clinical lead, you will have significant ownership and visibility, helping us make rigorous, patient-centered decisions as AL137 progresses through early clinical development.\nThis role is designed for a leader and “go-getter” who thrives through influence and hands-on contribution.\nKey Goals & Accountabilities\nLead the clinical development strategy for AL137!Own the clinical and medical strategy for Phase 1 and help shape the program's path toward later-stage development, integrating emerging clinical, translational, safety, and biomarker data into clear decisions.\n\nDeliver a high-quality Phase 1 program!Provide medical leadership for protocol design and execution, eligibility and safety considerations, dose escalation, clinical data review, and interpretation of emerging results while partnering closely with Clinical Operations and investigators.\n\nBe Alector's clinical voice!Serve as the internal physician expert for AL137 and provide clear clinical perspectives to program teams and senior leadership. Build productive relationships with investigators, external experts, partners, and regulatory authorities as appropriate.\n\nTurn data into decisions!Partner across Biometrics, Translational Medicine, Safety, Regulatory, and other functions to define evidence needed for critical development decisions and communicate the clinical meaning of emerging data.\n\nIntegrate innovative technologies, including AI, into clinical development!Identify practical ways to use AI and emerging technologies to accelerate analysis, improve decision-making, streamline clinical-development work, and conserve valuable time and resources.\n\nRequired Qualifications\nM.D. (Preferred) or Ph.D. in Neuroscience, Neurobiology, or equivalent field required.\n\n10+ years' experience leading clinical development in the biotechnology or pharmaceutical industry; experience taking programs through early clinical development is essential.\n\nServing as a subject matter authority (SME): Extensive clinical expertise in the management and execution of Alzheimer Disease (AD) and other related neurodegenerative disease programs. \nDrug development experience in neurodegenerative disease.\n\nStrong knowledge of clinical trial design, medical monitoring, clinical data interpretation, benefit-risk assessment, and the regulatory requirements supporting clinical drug development.\n\nExperience designing and executing first-in-human and Phase 1 and 2 studies, including dose escalation and interpretation of early safety, pharmacokinetic, pharmacodynamic, and biomarker data.\n\nExperience working with regulators and contributing clinical content to regulatory submissions and interactions.\n\nDemonstrated ability to exercise independent medical judgment and provide clinical leadership within cross-functional development teams; you are comfortable operating as the primary internal clinical expert for a program.\n\nAbility to translate complex scientific and clinical information into clear recommendations and collaborate effectively with scientists, development colleagues, executives, investigators, and external experts.\n\nYou are an active user of large language models (LLMs) and have a strong interest in evolving AI technologies and how they can improve the quality, speed, and efficiency of drug development.\n\nExperience working in a small or rapidly evolving biotechnology organization where clinical leaders combine strategic thinking with hands-on execution.","description_format":"text","description_chars":4034,"description_truncated":false,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Health Care","Neurology & CNS Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-21T23:41:03Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"Filed H-1B visas in the last two years","filings_12m":0,"filings_prev_12m":2,"green_card_filings_12m":0,"median_offered_wage_usd":null,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":19,"band":"cold","label":"Long shot","p_open":1,"p_active":0.686,"p_room":0.28,"age_days":72,"expected_fill_days":7,"reasons":["conf:3","urgency","win:tail","crowd:"],"computed_at":"2026-11-06T05:58:05Z"},"pay":{"stated_usd_annual":380000,"is_top_pay":true},"html_url":"https://alion.io/job/alector-vice-president-clinical-development","json_url":"https://alion.io/job/alector-vice-president-clinical-development.json","meta":{"generated_at":"2026-11-06T08:22:57Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":15014,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-07T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2939952},"rest":"https://alion.io/mcp/rest/get_company?id=2939952"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Falector-vice-president-clinical-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Falector-vice-president-clinical-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Falector-vice-president-clinical-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/alector-vice-president-clinical-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Falector-vice-president-clinical-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3043724}},{"tool":"search_jobs","arguments":{"company":"alector.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3043724},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); 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