{"id":3549500,"url":"https://alion.io/job/alnylam-scientist-proteomics","title":"Scientist, Proteomics","company":{"id":1776651,"name":"Alnylam","domain":"alnylam.com","url":"https://alion.io/company/alnylam","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"A","score":100,"open_postings":3,"ghost_share":0,"stale_share":0,"repost_share":0,"time_to_fill_p50_days":28,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Cambridge, United States","United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":66000,"max_usd":139000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":849},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Mass Spectrometry","optional":false},{"name":"MATLAB","optional":true},{"name":"Python","optional":true}],"status":"live","first_seen_at":"2026-10-30T18:51:09Z","employer_posted_date":"2026-10-30","last_verified_at":"2026-11-02T16:16:04Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"Overview:\nThe Translational Research Team at Alnylam is seeking a highly motivated Proteomics Scientist to join our LC/MS-based ‘omics group dedicated to advancing RNAi therapeutics through preclinical target validation, biomarker discovery, and innovation of novel delivery solutions for our RNAi therapeutics. The successful candidate will have a strong theoretical foundation in mass spectrometry and the skills needed to develop state-of-the-art workflows in spatial, single-cell, and subcellular proteomics from sample preparation through data analysis and interpretation. The individual will have excellent collaboration and communication skills to succeed in a fast-paced matrixed environment.\nThis position is onsite and will be primarily located in Cambridge, MA. \nKey Responsibilities: \nDrive sample preparation and LC/MS method development for novel experimental workflows including single cell, spatial, and subcellular proteomics using state-of-the-art instrumentation.\nDevelop novel data analysis and interpretation workflows optimized for next-generation proteomics technologies.\nCollaborate with an interdisciplinary team focused on identifying and characterizing novel receptors to unlock targeted delivery into new cell types and tissues.\nLeverage AI tools to inform novel receptor prediction based on protein sequence and structure.\nMaintain timely documentation and transparently communicate results with key stakeholders throughout the organization.\nQualifications: \nPhD in Bioengineering, Chemical Engineering, or related quantitative field.\n0-3 years of experience in biopharma setting.\nExpertise in LC/MS instrumentation and proteomics method development. Experience with Thermo Orbitrap is a plus.\nStrong computational background with proficiency in Python, Matlab or R. Experience with cloud computing and/or high-performance compute environments is preferred.\nExcellent communication skills (both written and oral) are essential.\nMust be self-motivated and thrive in a fast-paced team environment.\nFamiliarity with high-throughput sample preparation automation is preferred.\nStrong abilities to work both independently and in a team environment.\nIntellectual curiosity, a passion for science, critical thinking skills, and a willingness to ask questions.\nAbout Alnylam\nWe are the leader in RNAi therapeutics - a revolutionary approach with the potential to transform the lives of people with rare and common diseases. Built on Nobel Prize-winning science, Alnylam has delivered the breakthroughs that made RNAi therapeutics possible and are just at the beginning of what’s possible. Our deep pipeline, late-stage programs, and bold vision reflect our core values: fierce innovation, passion for excellence, purposeful urgency, open culture and commitment to people. We're proud to be a globally recognized top employer, where an authentic, inclusive culture and breakthrough thinking fuel one another.\nAt Alnylam, we commit to an inclusive recruitment process and equal employment opportunity. Qualified applicants will receive consideration for employment without regard to their sex, gender or gender identity, sexual orientation, race, color, ethnicity, national origin, ancestry, citizenship, religion, creed, physical or mental disability, pregnancy status or related conditions, genetic information, veteran or military status, marital or familial status, political affiliation, age, or any other factor protected by federal, state, or local law. Alnylam is an E-Verify Employer.\nBefore applying, please review Alnylam's Candidate Privacy Notice regarding how Alnylam handles Personal Data you provide with your application for employment.","description_format":"text","description_chars":3672,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Bioinformatics","Cell & Gene Therapy","Rare Disease Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-30T22:06:12Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 36 · green card filings: 9","filings_12m":36,"filings_prev_12m":48,"green_card_filings_12m":9,"median_offered_wage_usd":157500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":2,"expected_fill_days":28,"reasons":["conf:2","win:early","comp:junior"],"computed_at":"2026-11-02T06:13:15Z"},"pay":null,"html_url":"https://alion.io/job/alnylam-scientist-proteomics","json_url":"https://alion.io/job/alnylam-scientist-proteomics.json","meta":{"generated_at":"2026-11-02T17:04:19Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":23783,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1776651},"rest":"https://alion.io/mcp/rest/get_company?id=1776651"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Falnylam-scientist-proteomics"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Falnylam-scientist-proteomics"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Falnylam-scientist-proteomics"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/alnylam-scientist-proteomics\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Falnylam-scientist-proteomics"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3549500}},{"tool":"search_jobs","arguments":{"company":"alnylam.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3549500},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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