{"id":3373535,"url":"https://alion.io/job/ambry-genetics-senior-manager-software-engineering-data-architecture","title":"Senior Manager, Software Engineering (Data Architecture)","company":{"id":20123,"name":"Ambry Genetics","domain":"ambrygen.com","url":"https://alion.io/company/ambry-genetics","size_band":"501-1000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":92,"open_postings":3,"ghost_share":0,"stale_share":0.333,"repost_share":0,"time_to_fill_p50_days":41,"computed_at":"2026-10-30T05:48:23Z"}},"role":"Management","role_family":"Management","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Chicago, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":150000,"max":225000,"currency":"USD","period":"year","gross":null,"usd_annual":225000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Claude","optional":false},{"name":"Copilot","optional":false},{"name":"Cursor","optional":false},{"name":"dbt","optional":false},{"name":"Dimensional Modeling","optional":false},{"name":"Erwin","optional":false},{"name":"ETL/ELT","optional":false},{"name":"FHIR","optional":false},{"name":"GCP","optional":false},{"name":"Google BigQuery","optional":false},{"name":"Grafana","optional":false},{"name":"Machine Learning","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"Python","optional":false},{"name":"SQL","optional":false}],"status":"live","first_seen_at":"2026-10-27T00:00:00Z","employer_posted_date":"2026-10-27","last_verified_at":"2026-10-29T20:38:49Z","board_verified":true,"closed_at":null,"days_open":3,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":3},"description":"Passionate about precision medicine and advancing the healthcare industry?\nRecent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.\nAbout Tempus\nTempus is on a mission to create the world’s largest integrated dataset of clinical and molecular data. We believe that, through data, we can make a lasting contribution to cancer research and treatment. At Tempus, products are owned and developed by small, autonomous teams of developers, designers, data scientists, and product managers who work together to build a platform that is both nimble and innovative.\nThe Role\nAs Senior Manager, Software Engineering, you will lead and mentor a small team of data engineers and data architects, and you will own the enterprise data model and the reliability of the data it represents. You will design how clinical records, genomics, next-generation sequencing (NGS) laboratory data, and radiology data are integrated, and you will ensure that the data are accurate, traceable, and suitable for critical applications such as machine learning and clinical decision-making.\nYou will establish modeling standards, implement quality gates in data pipelines, and develop the team through design review, code review, and ongoing coaching. You will use development tools assisted by artificial intelligence (AI) to accelerate design, testing, and delivery.\nWhat You Will Do\nLead and mentor a small team of data engineers and data architects by conducting design and code reviews, providing technical guidance, and fostering a culture of excellence in data architecture and data quality.\nOwn and evolve an enterprise data model with engineers, product managers, scientists, and operators, integrating structured data from clinical records, genomics, the NGS laboratory, and radiology across relational and NoSQL data stores. Author and maintain entity-relationship diagrams, data dictionaries, API specifications, and data-translation documentation at the conceptual, logical, and physical levels.\nApply modern data architecture best practices and patterns, and teach modeling standards, including third normal form, dimensional (star schema) design, and established healthcare data model standards such as FHIR, OMOP, and related standards.\nEvaluate the completeness of source-system models and partner data through profiling, and resolve structural inconsistencies before they reach downstream consumers.\nDesign observability for the data ecosystem with BigQuery, dbt, Elementary, and Grafana, including monitors, alerts, dashboards, lineage, and traceability back to source systems.\nPartner with product managers and engineering leads to prioritize the backlog, estimate work, and translate complex requirements into actionable technical tasks. Advance the use of AI-assisted development, including Cursor, Claude, and GitHub Copilot, to accelerate modeling, testing, refactoring, and pipeline development.\nWhy We Are Looking for You\nYou have a record of leading and mentoring a small team of data engineers and data architects, of setting standards, and of guiding design in a fast-paced environment. You can translate gaps in the data model and in data quality into clear recommendations for engineers, scientists, and other stakeholders.\nYou are an expert in the modern data stack, particularly dbt, SQL, and Python, and you have demonstrated exceptional SQL skills in an enterprise data warehouse. You are proficient in the use of AI coding assistants such as Cursor, Claude, and GitHub Copilot.\nYou have applied modern data architecture best practices and patterns, and you can guide a team in their use. You have strong experience with third normal form (3NF) and dimensional (star schema) modeling; with established healthcare data model standards such as FHIR, OMOP, and related standards; and with modeling tools such as Erwin, Vertabelo, or Lucidchart.\nYou understand ETL/ELT and business intelligence (BI) architectures, and you can explain the long-term implications of choosing among relational, massively parallel processing (MPP), and NoSQL technologies. You have architected solutions across more than one of these technologies.\nYou have practical experience with data observability (for example, Elementary and Grafana) and with profiling and correlation analysis to identify data-integrity problems.\nYou have domain experience in healthcare and next-generation sequencing, including clinical and genomic data.\nPreferred\nDeep knowledge of Google Cloud Platform (GCP) and BigQuery architecture.\nExperience modeling NGS data output.\nExperience in implementing master data, reference data, or metadata management.\nWhy Join Tempus\nYou will work at the intersection of software engineering and cancer research. In this role, you will lead a small team of data engineers and data architects and shape the data model and quality systems that make Tempus data reliable enough for research and clinical use.\n$150,000 - $225,000\nThe expected salary range may vary for other locations. Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.\nWe are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.","description_format":"text","description_chars":5711,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Restricted stock units"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Genomics & Genetic Testing","Medical Laboratories"],"lifecycle":[{"event":"open","at":"2026-10-28T01:58:46Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 3","filings_12m":3,"filings_prev_12m":4,"green_card_filings_12m":0,"median_offered_wage_usd":157500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":90,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.903,"p_room":1,"age_days":3,"expected_fill_days":41,"reasons":["conf:9","velocity","win:early"],"computed_at":"2026-10-30T05:48:23Z"},"pay":{"stated_usd_annual":225000,"is_top_pay":true},"html_url":"https://alion.io/job/ambry-genetics-senior-manager-software-engineering-data-architecture","json_url":"https://alion.io/job/ambry-genetics-senior-manager-software-engineering-data-architecture.json","meta":{"generated_at":"2026-10-30T07:54:49Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":11129,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-31T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":20123},"rest":"https://alion.io/mcp/rest/get_company?id=20123"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fambry-genetics-senior-manager-software-engineering-data-architecture"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fambry-genetics-senior-manager-software-engineering-data-architecture"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fambry-genetics-senior-manager-software-engineering-data-architecture"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/ambry-genetics-senior-manager-software-engineering-data-architecture\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fambry-genetics-senior-manager-software-engineering-data-architecture"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3373535}},{"tool":"search_jobs","arguments":{"company":"ambrygen.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3373535},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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