{"id":3684806,"url":"https://alion.io/job/amgen-director-local-study-operations-manager","title":"Director, Local Study Operations Manager","company":{"id":4775,"name":"Amgen","domain":"amgen.com","url":"https://alion.io/company/amgen","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":85,"open_postings":344,"ghost_share":0,"stale_share":0.605,"repost_share":0.02,"time_to_fill_p50_days":43,"computed_at":"2026-11-04T06:34:25Z"}},"role":"Management","role_family":"Management","seniority":"head","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Thousand Oaks, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":195876,"max":265008,"currency":"USD","period":"year","gross":null,"usd_annual":265008},"salary_estimate":null,"experience_years_min":9,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GCP","optional":false},{"name":"Good Clinical Practice","optional":true},{"name":"ICH Guidelines","optional":true}],"status":"live","first_seen_at":"2026-11-02T00:00:00Z","employer_posted_date":"2026-11-02","last_verified_at":"2026-11-04T10:50:26Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"Career Category\nClinicalJob Description\nJoin Amgen’s Mission of Serving Patients\nAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.\nSince 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. Amgen is advancing a broad and deep pipeline and portfolio of medicines to treat heart disease, obesity and obesity-related conditions, rare diseases, inflammatory conditions and cancer. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.\nOur award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.\nLocal Study Operations Manager (LSOM), Director\nWhat you will do\nLet’s do this. Let’s change the world. In this vital role you will provide strategic and operational leadership for the country LSOM organization and is accountable for the quality, timeliness, cost, and compliant execution of the country clinical study portfolio. The role achieves results through LSOM Senior Managers and their FTE and FSP teams, translating global clinical development strategy into country operating priorities. The role directs portfolio delivery, resource and capacity strategy, financial planning, quality and risk management, vendor performance, and inspection readiness from feasibility through study close-out. As a member of the country leadership team, this role influences study placement and portfolio decisions, leads the resolution of significant operational issues, develops organizational capability and succession plans, and represents LSOM operations in country, regional, and global governance forums.\nAccountabilities \nLead the successful delivery of the country study portfolio through the LSOM management organization, ensuring alignment with global clinical development priorities. \nProvides strategic direction and leadership to LSOM country organization across the full study lifecycle, including feasibility, study execution, and study close-out. \nEstablishes portfolio-level oversight of delivery, quality, risk, timelines, and performance, directing timely escalation and resolution of critical issues for LSOM management organization. \nManage LSOM and LSOM vendor performance to guarantee high-quality study execution, serving as the primary escalation point for local study challenges, driving solutions, and ensuring portfolio targets are met within the country. \nBuild leadership capability within the LSOM organization through targeted coaching, development, and succession planning, preparing LSOMs to lead increasingly complex trials and programs. \nEstablishes strong operating partnerships with Clinical Research Associate (CRA) organization to support study start-up, monitoring, issue resolution, and compliant trial execution across the country portfolio. \nCultivate a high-performing, accountable, and inclusive organization focused on operational excellence and continuous improvement. \nChampion strong integration between study strategy and local execution teams to translate portfolio priorities into effective country-level delivery. \nStrengthen cross-functional alignment and accountability across country teams to accelerate execution and deliver portfolio commitments. \nInfluences study-placement and portfolio investment decisions by providing strategic insight into country's capabilities, operational readiness, performance, and growth potential. \nAnticipates portfolio-level delivery risks, quality trends, and evolving resource requirements, directing mitigation strategies and systemic improvements across country operations. \nSponsor initiatives that advance operational efficiency, digital innovation, organizational capability, and the adoption of leading practices. \nDirect resource strategy, capacity planning, and workload allocation across FSP and FTE LSOM teams to optimize execution and align resources with global priorities. \nEnsure compliance with applicable regulatory, GCP, ICH, and organizational standards across the country's study portfolio. \nPartner with the Regional Head/Country Head and senior cross-functional stakeholders to align priorities, establish accountability for trial deliverables, and resolve significant escalations. \nResponsibilities\nServe as the functional leader for LSOM Senior Managers and the broader LSOM team, including both FSP and FTE, to optimize trial execution and align with global priorities. including strategy and execution, managing risks and escalations \nPartners closely with CRAs, CSPO, Quality, and FSP partners. \nLeads the coordination among country functional teams to ensure successful delivery of the country portfolio. \nEnsure inspection readiness and provide hands-on support during inspections, including responsibility for storyboards. \nSponsors continuous operational improvement initiatives and encourage sharing of best practices. \nEnsure compliance with relevant regulatory and quality standards. \nCollaborate with the Regional Head/Country Head to engage cross-functional stakeholders, align on trial deliverables, and manage escalations as needed. \nCapability Building and People Leadership\nLead, coach, and develop LSOM Sr Managers, including performance management, succession planning, and leadership bench development. \nBuild the organizational capabilities, resourcing needed to meet the current and future regional portfolio requirements. \nFoster a high-performing, inclusive, accountable, and patient-focused culture across geographically distributed teams. \nLead organizational changes and enable adoption of new operating models, technologies \nAuthority\nAccountable for country level oversight and delivery of clinical trials. \nManage the performance of LSOM Senior Managers and their teams \nHolds line management authority for regional and country operations leaders, including performance management, talent development, succession planning, and capability building. \nSets regional delivery goals, operating expectations, and performance standards across study start-up, site engagement, monitoring, execution, and closeout. \nCapability build, talent and performance management, and acting as a liaison for cultural differences within region. \nOutputs\nManage LSOM resources in accordance with the global study strategy. \nOversee resource allocation and workload balance across LSOMs. \nHandle FSP supplier resource coordination and monitor performance through quality oversight metrics. \nIdentify and report any risks or compliance concerns related to FSP activities. \nEscalate issues to the Regional/Country Head as necessary. \nWhat we expect of you\nBasic Qualifications:\nDoctorate degree and 4 years of clinical research experience OR\nMaster’s degree and 7 years of clinical research experience OR\nBachelor’s degree and 9 years of clinical research experience\nPreferred Qualifications:\n4 years of direct managerial and/or leadership experience or equivalent \nDeep knowledge of ICH GCP, ICH E6(R3), ICH E8(R1), and global regulatory expectations for risk-based monitoring and clinical trial oversight. \nProven ability to influence senior stakeholders and lead complex cross-functional initiatives within a global matrix organization \nStrong Project Management experience \nExperience managing multiple teams / direct reports across multiple clinical functions / trials \nExperience at, or oversight of, clinical research vendors (CROs, central labs, imaging vendors, etc.) \nExperience managing clinical operations across relevant geography / region, including strong understanding of local regulatory requirements around global clinical trials \nWhat you can expect of us\nAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.\nThe expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.\nBase Salary Range: $195,876-265,008\nIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:\nA comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts\nA discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan\nStock-based long-term incentives\nAward-winning time-off plans\nFlexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.\nApply now and make a lasting impact with the Amgen team.\ncareers.amgen.com\nIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.\nApplication deadline\nExternal/Internal postings:\nAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.\nSponsorship\nSponsorship for this role is not guaranteed.\nAs an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.\nAmgen is an Equal Opportunity employer. We make all employment decisions without regard to race, color, religion, sex or any other characteristic protected by applicable law.\nWe provide reasonable accommodations to applicants and employees with disabilities, consistent with legal requirements. Please contact us to request accommodation.\n.Salary Range\nUSD - USD","description_format":"text","description_chars":10621,"description_truncated":false,"requirements":{"experience_years_min":9,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Flexible schedule","Retirement plans"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[{"name":"Puerto Rico","iso":"PR"}],"relocation_offered":false,"industries":["Prescription Drugs","Biologics & Biosimilars","Immunology & Inflammation Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-03T14:27:39Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 372 · green card filings: 113","filings_12m":372,"filings_prev_12m":465,"green_card_filings_12m":113,"median_offered_wage_usd":136675,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.632,"p_room":1,"age_days":2,"expected_fill_days":43,"reasons":["conf:1","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-11-04T06:34:25Z"},"pay":{"stated_usd_annual":265008,"is_top_pay":true},"html_url":"https://alion.io/job/amgen-director-local-study-operations-manager","json_url":"https://alion.io/job/amgen-director-local-study-operations-manager.json","meta":{"generated_at":"2026-11-04T11:05:35Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":16435,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-05T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4775},"rest":"https://alion.io/mcp/rest/get_company?id=4775"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Famgen-director-local-study-operations-manager"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Famgen-director-local-study-operations-manager"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Famgen-director-local-study-operations-manager"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/amgen-director-local-study-operations-manager\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Famgen-director-local-study-operations-manager"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3684806}},{"tool":"search_jobs","arguments":{"company":"amgen.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3684806},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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