{"id":1565830,"url":"https://alion.io/job/amgen-principal-data-scientist","title":"Principal Data Scientist","company":{"id":4775,"name":"Amgen","domain":"amgen.com","url":"https://alion.io/company/amgen","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":79,"open_postings":401,"ghost_share":0.002,"stale_share":0.838,"repost_share":0.007,"time_to_fill_p50_days":28,"computed_at":"2026-10-10T05:45:15Z"}},"role":"Data Science","role_family":"Data Science","seniority":"lead","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Thousand Oaks, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":160896,"max":217683,"currency":"USD","period":"year","gross":null,"usd_annual":217683},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"Knowledge Graph","optional":false},{"name":"AWS","optional":true},{"name":"Azure","optional":true},{"name":"CI/CD","optional":true},{"name":"Context Engineering","optional":true},{"name":"Databricks","optional":true},{"name":"Function Calling","optional":true},{"name":"GCP","optional":true},{"name":"GraphRAG","optional":true},{"name":"Human-in-the-Loop","optional":true},{"name":"LangChain","optional":true},{"name":"LangGraph","optional":true},{"name":"LlamaIndex","optional":true},{"name":"LLM Guardrails","optional":true},{"name":"LLMOps","optional":true},{"name":"Machine Learning","optional":true},{"name":"MLFlow","optional":true},{"name":"Multi-Agent Systems","optional":true},{"name":"Python","optional":true},{"name":"PyTorch","optional":true},{"name":"RAG","optional":true},{"name":"Scikit-learn","optional":true},{"name":"Spark","optional":true},{"name":"SQL","optional":true},{"name":"TensorFlow","optional":true},{"name":"Tool Use","optional":true}],"status":"closed","first_seen_at":"2026-09-29T00:00:00Z","employer_posted_date":"2026-09-29","last_verified_at":"2026-10-11T09:52:40Z","board_verified":false,"closed_at":"2026-10-11T09:52:40Z","days_open":12,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":12},"description":"Career Category\nOperationsJob Description\nJoin Amgen’s Mission of Serving Patients\nAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.\nSince 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.\nOur award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.\nPrincipal Data Scientist\nWhat you will do\nLet’s do this. Let’s change the world. In this vital role you will play a key part in designing, developing, and deploying scalable AI/ML solutions and agentic systems to drive innovation, efficiency, and regulatory compliance across the organization.\nYou will collaborate with multi-functional teams, including software engineers, data engineers, business partners, and quality professionals to design and implement responsible and ethical AI-driven capabilities that support strategic business objectives.\nInnovation & Research Translation: Stay at the forefront of AI/ML advancements-especially in the agentic AI and knowledge graph spaces-and translate emerging techniques into enterprise-ready applications.\nAgentic System Design & Innovation: Architect and deploy agent-based and multi-agent AI/ML systems to enhance automation, decision-making, and operational efficiency, leveraging modern frameworks and GenAI capabilities.\nData Excellence & MLOps Governance: Champion robust data science practices and develop scalable, auditable MLOps pipelines. Enforce standards for versioning, testing, monitoring, documentation, and security to ensure high-quality model lifecycle management.\nEnterprise Integration & Cross-Functional Alignment: Partner with technology, product, and business team members to align AI initiatives with enterprise goals. Ensure solutions are traceable, interoperable, and embedded within Amgen’s digital Quality ecosystem.\nResponsible & Ethical AI: Embed principles of ethical AI-including fairness, transparency, privacy, and explain-ability-into the design and deployment of AI/ML solutions. Ensure alignment with Amgen’s Quality and Compliance standards and global regulatory frameworks.\nWhat we expect of you\nWe are all different, yet we all use our unique contributions to serve patients. The professional we seek is a go getter with these qualifications.\nBasic Qualifications:\nDoctorate degree and 2 years of Data Science, Software/ML Engineering, experience\nOR\nMaster’s degree and 4 years of Data Science, Software/ML Engineering, experience\nOR\nBachelor’s degree and 6 years of Data Science, Software/ML Engineering, experience\nOR\nAssociate’s degree and 10 years of Data Science, Software/ML Engineering, experience \nOR\nHigh school diploma / GED and 12 years of Data Science, Software/ML Engineering, experience\nPreferred Qualifications:\nDemonstrated success providing technical leadership to teams delivering AI, machine learning, generative AI, analytics, or intelligent automation products in production.\nExperience delivering AI-enabled solutions within GxP-regulated biotechnology, pharmaceutical, healthcare, or life-sciences environments.\nStrong understanding of GxP principles, data integrity, computer-system validation, risk-based validation, change control, and regulated model lifecycle management.\nProven expertise designing and implementing AI, machine learning, and generative AI applications, including agent-based or multi-agent systems.\nExperience with frameworks and patterns such as LangChain, LangGraph, LlamaIndex, retrieval-augmented generation, GraphRAG, vector search, and knowledge graphs.\nAdvanced proficiency in Python and common machine-learning libraries such as PyTorch, TensorFlow, scikit-learn, or equivalent technologies.\nExperience with large language models, prompt and context engineering, tool calling, model evaluation, guardrails, and human-in-the-loop design.\nProficiency with data-engineering technologies and methods, including SQL, Apache Spark, data pipelines, data modeling, and distributed processing.\nExperience developing full-stack applications and integrating AI solutions with enterprise platforms, APIs, data products, and business workflows.\nStrong knowledge of MLOps and LLMOps practices and tools, including MLflow, CI/CD pipelines, automated testing, observability, model monitoring, and infrastructure as code.· Experience with cloud and data platforms such as Databricks, AWS, Microsoft Azure, or Google Cloud Platform.\nDemonstrated ability to manage a portfolio of AI opportunities, balance experimentation with production delivery, and connect technical outcomes to measurable business value.\nExperience developing reusable AI capabilities, technical standards, enablement materials, or communities of practice.· Strong problem-solving skills and the ability to operate effectively in complex, ambiguous, and rapidly evolving environments.\nExcellent written and verbal communication skills, with the ability to influence technical, business, quality, and executive stakeholders.\nDemonstrated ability to mentor others, lead through influence, and build productive relationships across functions and geographies.\nHigh degree of initiative, accountability, self-motivation, and effectiveness in global, cross-functional teams.\nWhat you can expect of us\nAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.\nThe expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.\nIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:\nA comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts\nA discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan\nStock-based long-term incentives\nAward-winning time-off plans\nFlexible work models where possible. Refer to the Work Location Type in the job posting to see if this applies.\nApply now and make a lasting impact with the Amgen team.\ncareers.amgen.com\nIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.\nApplication deadline\nAmgen does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.\nSponsorship\nSponsorship for this role is not guaranteed.\nAs an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.\nAmgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.\nWe will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.\n.\nSalary Range\n160,896.50USD -217,683.50 USD","description_format":"text","description_chars":8859,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"high_school","optional":false},"security_clearance":false,"languages":[]},"benefits":["Flexible schedule","Retirement plans"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[{"name":"Puerto Rico","iso":"PR"}],"relocation_offered":false,"industries":["Biotechnology","Health Care","Immunology & Inflammation Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-01T06:01:42Z"},{"event":"close","at":"2026-10-11T09:52:40Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 372 · green card filings: 113","filings_12m":372,"filings_prev_12m":465,"green_card_filings_12m":113,"median_offered_wage_usd":136675,"route":null,"cap_exempt":false,"checked_at":"2026-10-03T21:08:04+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":74}],"liveness":null,"pay":{"stated_usd_annual":217683,"is_top_pay":true},"html_url":"https://alion.io/job/amgen-principal-data-scientist","json_url":"https://alion.io/job/amgen-principal-data-scientist.json","meta":{"generated_at":"2026-10-12T01:13:25Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":1337,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-13T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4775},"rest":"https://alion.io/mcp/rest/get_company?id=4775"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Famgen-principal-data-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Famgen-principal-data-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Famgen-principal-data-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/amgen-principal-data-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Famgen-principal-data-scientist"}]}