{"id":3403956,"url":"https://alion.io/job/amgen-scientific-associate-director-project-toxicologist","title":"Scientific Associate Director - Project Toxicologist","company":{"id":4775,"name":"Amgen","domain":"amgen.com","url":"https://alion.io/company/amgen","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":85,"open_postings":344,"ghost_share":0,"stale_share":0.576,"repost_share":0.012,"time_to_fill_p50_days":43,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Biotech","role_family":"Biotech","seniority":"head","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Thousand Oaks, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":194274,"max":262841,"currency":"USD","period":"year","gross":null,"usd_annual":262841},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-08-20T00:00:00Z","employer_posted_date":"2026-08-20","last_verified_at":"2026-11-02T01:01:50Z","board_verified":true,"closed_at":null,"days_open":74,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":74},"description":"Career Category\nScientificJob Description\nJoin Amgen’s Mission of Serving Patients\nAt Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission-to serve patients living with serious illnesses-drives all that we do.\nSince 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas -Oncology, Inflammation, General Medicine, and Rare Disease- we reach millions of patients each year. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.\nOur award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.\nScientific Associate Director - Project Toxicologist\nWhat you will do\nLet’s do this. Let’s change the world. In this vital role, you will serve as the key scientific interface between Translational Safety & Risk Sciences (TSRS) and cross-functional project teams from discovery through post-marketing. TSRS is seeking a Scientific Associate Director to serve as a Project Toxicologist and subject matter expert, reporting to a Senior Director Project Team Representative (PTR) Manager.\nYou will be responsible for developing and implementing fit-for-purpose nonclinical safety strategies built on a rigorous scientific foundation and aligned with regulatory expectations. As programs evolve, you will flexibly adapt strategies in response to emerging data, and project team needs while leading multidisciplinary TSRS teams. As a PTR, you will partner closely with project teams developing innovative therapeutics across a range of modalities-including biotherapeutics, small molecules, targeted protein degraders, and other complex modalities (e.g. RNA-based therapies) for indications in inflammation, rare diseases, oncology, and cardiometabolic diseases, including obesity. PTRs are encouraged to develop subject matter expertise in a specific modality, therapeutic area, or sub-discipline within nonclinical safety (e.g. drug-induced liver toxicity).\nKey Responsibilities\nServe as TSRS PTR (nonclinical safety representative) on core project teams and lead the TSRS sub-team. The TSRS PTR is a key ambassador for the TSRS mission: Driving translational safety strategy and innovation to inform human risk with precision, insight, and impact, accelerating transformative therapies to patients.\nLead and coordinate the TSRS sub-team, fully leveraging the TSRS advisory network to inform human risk assessment, shape development strategy, and enable confident project decisions.\nDesign, implement, oversee, and interpret nonclinical safety assessment programs supporting drug development candidates with an enterprise-wide mindset.\nDevelop innovative study designs and nonclinical assessment strategies to address complex scientific questions, integrating AI-enabled approaches and New Approach Methodologies (NAMs) to enhance translational risk assessment and support critical development decisions.\nCritically evaluate and interpret experimental data and author key sections of nonclinical strategy, governance and regulatory submissions, including first-in human trial applications and marketing authorizations.\nCommunicate effectively, both orally and in writing, within TSRS and across core project teams, leadership, governance bodies, and regulatory agencies, tailoring communications to the needs and expertise of diverse audiences.\nOperate effectively in a fast-paced, highly matrixed environment, balancing the needs of multiple project teams and stakeholders while ensuring proactive communication, strategic prioritization, and timely delivery of TSRS contributions.\nCollaborate closely with internal Amgen scientists and external partners to advance research and development programs.\nContribute to business development activities, including licensing evaluations, due diligence assessments, and external partnerships, as appropriate.\nMentor and support fellow scientists in the design, execution, interpretation, and oversight of nonclinical studies and development programs.\nWhat we expect of you\nWe are all different, yet we all use our unique contributions to serve patients. The scientific leader we seek is collaborative, strategic, and comfortable influencing across multidisciplinary teams, with these qualifications.\nBasic Qualifications:\nDoctorate degree (PhD, PharmD, or MD) and 4 years of Toxicology experience\nOr\nMaster’s degree and 7 years of Toxicology experience\nOr\nBachelor’s degree and 9 years of Toxicology experience\nPreferred Qualifications:\nA minimum of 8 years of drug development experience as a Project Toxicologist/Nonclinical Safety Project Team Representative at all stages of development including late-stage assets and interactions with global regulatory agencies for first-in human trial applications and marketing authorizations.\nEnd-to-end small- and large-molecule safety assessment experience across multiple therapeutic areas and modalities\nPreferred experience in nonclinical safety assessment of siRNA therapeutics, antibody-drug conjugates (ADCs), antibody-peptide conjugates, and/or targeted protein degraders\nDemonstrate a proven ability to serve as a highly effective cross-functional thought partner, driving alignment and advancing complex scientific discussions across R&D functions\nSubject matter expertise in a defined area of toxicology (e.g. drug-induced liver injury)\nExperience supporting business development efforts through due diligence evaluations as a translational safety team member\nScientific leader with matrixed management experience\nBoard certification by the American Board of Toxicology\nExcellent communicator with a proven ability to influence a broad spectrum of partners toward achieving business goals\nExternal visibility as a toxicology subject matter expert, demonstrated by external presentations and publications and/or leadership or active participation in external collaborative groups\nWhat you can expect of us\nAs we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we’ll support your journey every step of the way.\nThe expected annual salary range for this role in the U.S. (excluding Puerto Rico) is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.\nIn addition to the base salary, Amgen offers a Total Rewards Plan, based on eligibility, comprising health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities that may include:\nA comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts\nA discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan\nStock-based long-term incentives\nAward-winning time-off plans\nFlexible work models, including remote and hybrid work arrangements, where possible\nApply now and make a lasting impact with the Amgen team.\ncareers.amgen.com\nIn any materials you submit, you may redact or remove age-identifying information such as age, date of birth, or dates of school attendance or graduation. You will not be penalized for redacting or removing this information.\nApplication deadline\nAmgen does not have an application deadline for this position; we will continue accepting applications until we receive enough or select a candidate for the position.\nSponsorship\nSponsorship for this role is not guaranteed.\nAs an organization dedicated to improving the quality of life for people around the world, Amgen fosters an inclusive environment of diverse, ethical, committed and highly accomplished people who respect each other and live the Amgen values to continue advancing science to serve patients. Together, we compete in the fight against serious disease.\nAmgen is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or any other basis protected by applicable law.\nWe will ensure that individuals with disabilities are provided reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment. Please contact us to request accommodation.\n.Salary Range\n194,274.30USD -262,841.70 USD","description_format":"text","description_chars":9050,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Flexible schedule","Hybrid work","Retirement plans"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[{"name":"Puerto Rico","iso":"PR"}],"relocation_offered":false,"industries":["Prescription Drugs","Biologics & Biosimilars","Immunology & Inflammation Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-28T15:30:05Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 372 · green card filings: 113","filings_12m":372,"filings_prev_12m":465,"green_card_filings_12m":113,"median_offered_wage_usd":136675,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":20,"band":"cold","label":"Long shot","p_open":1,"p_active":0.56,"p_room":0.36,"age_days":74,"expected_fill_days":43,"reasons":["conf:5","stale_co","velocity","win:tail","crowd:brand"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":262841,"is_top_pay":false},"html_url":"https://alion.io/job/amgen-scientific-associate-director-project-toxicologist","json_url":"https://alion.io/job/amgen-scientific-associate-director-project-toxicologist.json","meta":{"generated_at":"2026-11-02T07:13:22Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":10193,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4775},"rest":"https://alion.io/mcp/rest/get_company?id=4775"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Famgen-scientific-associate-director-project-toxicologist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Famgen-scientific-associate-director-project-toxicologist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Famgen-scientific-associate-director-project-toxicologist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/amgen-scientific-associate-director-project-toxicologist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Famgen-scientific-associate-director-project-toxicologist"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3403956}},{"tool":"search_jobs","arguments":{"company":"amgen.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3403956},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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