{"id":2669441,"url":"https://alion.io/job/amylyx-associate-director-data-architect","title":"Associate Director, Data Architect","company":{"id":2594505,"name":"Amylyx","domain":"amylyx.com","url":"https://alion.io/company/amylyx","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":75,"open_postings":4,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-10-16T05:45:00Z"}},"role":"Data Science","role_family":"Data Science","seniority":"head","employment_type":null,"work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"posting_text","remote_working_hours":null,"hiring_geo_confidence":"inferred","locations":["Cambridge, United States"],"countries":["US"],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":190000,"max":206000,"currency":"USD","period":"year","gross":null,"usd_annual":206000},"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"ETL/ELT","optional":false},{"name":"Machine Learning","optional":false},{"name":"Master Data Management","optional":false},{"name":"Power BI","optional":false},{"name":"Python","optional":false},{"name":"Rest API","optional":false},{"name":"Snowflake","optional":false},{"name":"SQL","optional":false},{"name":"Talend","optional":false},{"name":"Wolfram","optional":false}],"status":"live","first_seen_at":"2026-09-15T12:44:47Z","employer_posted_date":"2026-09-16","last_verified_at":"2026-10-16T09:00:35Z","board_verified":true,"closed_at":null,"days_open":30,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":30},"description":"Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).\nOur mission is powered by our people. Our core values - be audacious, be curious, be authentic, be engaged, and be accountable - creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.\nThe Opportunity\nAmylyx Pharmaceuticals is seeking a highly motivated Associate Director, Data Architecture to lead the design, implementation, and evolution of our enterprise data platform as we prepare for commercial growth and future product launches.\nThis individual will play a key role in building a scalable, modern data ecosystem centered on Snowflake, enabling trusted, high-quality data across Commercial, Medical Affairs, Patient Services, Finance, R&D, Quality, and Corporate functions. The role combines enterprise data architecture, solution delivery leadership, and stakeholder engagement.\nThe successful candidate will serve as the technical lead for enterprise data initiatives and will partner closely with business stakeholders, external vendors, managed service providers, and implementation partners to establish a robust and scalable data foundation that supports operational excellence, analytics, reporting, and AI-enabled insights.\nThis is a hands-on leadership role requiring both strategic vision and deep technical expertise across data architecture, integration, data engineering, data governance, and business intelligence.\nResponsibilities\nEnterprise Data Architecture\nDefine and maintain Amylyx's enterprise data architecture roadmap and target-state data platform.\nLead data architecture and solution design for new business domains including Commercial, Finance, HR, R&D, Quality, and Regulatory.\nEstablish scalable data architecture patterns for ingestion, transformation, storage, governance, reporting, and analytics.\nDevelop and maintain enterprise data models, canonical data structures, and integration standards.\nCommercial Data Platform & Launch Readiness\nLead development and expansion of Amylyx's Commercial Data Hub and enterprise data warehouse.\nDesign and oversee integration of key commercial data sources including:CRM, Specialty Pharmacy, Specialty Distributor, Patient Services, Claims and Prescription Data, Formulary and Market Access Data, Customer Master Data, etc.\n\nSupport commercial launch planning through delivery of high-quality, trusted data and reporting capabilities.\nCollaborate with Commercial Operations and Analytics teams to enable KPI reporting, territory management, incentive compensation, customer analytics, and launch performance tracking.\nData Engineering & Integration\nProvide technical leadership for Snowflake-based data solutions.\nDesign and oversee ELT/ETL processes utilizing Snowflake, SQL, Python, Talend/Qlik Data Integration, APIs, and cloud-native technologies.\nDefine standards for data ingestion, transformation, orchestration, monitoring, and automation.\nReview and approve technical designs, code, and implementation deliverables from internal and external teams.\nDrive optimization of performance, scalability, security, and maintainability across the platform.\nData Governance & Master Data Management\nPartner with business and IT leaders to establish data governance processes and standards.\nSupport enterprise MDM strategy and implementation.\nDefine standards for data quality, metadata, lineage, reference data, and stewardship.\nEnsure compliance with applicable GxP, privacy, security, and regulatory requirements.\nLeadership & Vendor Management\nAct as the primary technical lead for data architecture initiatives and strategic programs.\nManage relationships with implementation partners, managed service providers, and data vendors.\nEstablish best practices, development standards, code review processes, and operational procedures.\nMentor technical resources and contribute to building a Data & Analytics Center of Excellence.\nRequired Qualifications\nBachelor's degree in Computer Science, Information Systems, Engineering, or related discipline.\n10+ years of experience in Data Architecture, Data Engineering, Data Warehousing, or Business Intelligence.\n5+ years leading enterprise-scale data architecture initiatives.\n3+ years of hands-on experience designing and implementing solutions on Snowflake.\nExperience supporting commercial operations within pharmaceutical or biotechnology organizations.\nStrong experience designing and implementing modern data warehouses, data lakes, and analytical platforms.\nExpertise with:Snowflake, SQL/SnowSQL, Python, Talend/Qlik Data Integration, Power BI\n\nREST APIs and enterprise integrations\nStrong knowledge of:Data modeling, Data governance, MDM, Data quality frameworks, Security and access controls\n\nExperience designing end-to-end solutions from source systems through reporting and analytics.\nExperience managing implementation partners, consultants, and managed service providers.\nAbility to effectively communicate complex technical concepts to executive, business, and technical audiences.\nExperience designing data products that support AI, machine learning, or GenAI initiatives.\nExperience implementing enterprise data governance or MDM programs.\nWork Location and Conditions\nAt Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations related to health insurance coverage and state tax regulations, we are unable to hire employees who reside and/or work in certain states. Currently, we are not considering applicants from Alaska, Arizona, Hawaii, Michigan and Tennessee.\nPreference will be given to candidates who reside in the New England region and can be in person on an as needed basis.\nIf outside of the New England region, you will be expected to travel to our corporate location in Cambridge, MA several times a year and attend other company-related events as necessary and requested, which may include travel by air, driving or public transportation.\nWhen working remotely, you must have access to a work setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.\nCompensation\nThe pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.\nEstimated Pay Range\n$190,000—$206,000 USD\nTo stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.\nTo return to our website please click here.\nAmylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.\nIt is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. 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