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Salary
$120k – $135k per year
Location
Hybrid (Cambridge, United States)
Seniority
Staff · 8+ years exp

Confirmed on the employer's own hiring board on Oct 19, 2026. First seen by Alion on Oct 2, 2026. Amylyx scores B on the Alion truth index.

Overview
Company
Impact
Profile match
Ushering in a new era for treating diseases with high unmet needs. We have an audacious mission to develop novel therapies for communities with high unmet needs. Where others see obstacles, the Amylyx team sees opportunities to find solutions for some of medicine's toughest challenges.

Amylyx has an audacious mission to usher in a new era for treating diseases with high unmet needs. Where others see challenges, we see opportunities that we pursue with urgency, rigorous science, and unwavering commitment to the communities we serve. We are a clinical-stage company currently focused on post-bariatric hypoglycemia (PBH), Wolfram syndrome, and amyotrophic lateral sclerosis (ALS).

Our mission is powered by our people. Our core values - be audacious, be curious, be authentic, be engaged, and be accountable - creating a culture of caring. Amylyx has assembled an experienced team ready to take action because the communities we serve have no time to wait. If you share our passion and are determined to tackle some of medicine’s toughest problems, we encourage you to read the opportunity below and apply.

The Opportunity

Amylyx is seeking an Executive Assistant, Commercial, to provide executive level administrative support to the Chief Commercial Officer and administrative support to the Commercial Leadership Team. In this visible role, the Executive Assistant, Commercial, is responsible for proactively listening, anticipating and meeting priorities in a fast-paced environment. Must be a team player, responsive and able to function independently, manage highly confidential and sensitive information and matters with the utmost discretion.

The person in this role will have exceptional written and verbal communication skills, with the ability to create and edit communications, meeting notes when required, meeting preparation materials, and presentations, ensuring accuracy, attention to detail, and follow through. This position offers a unique opportunity to be part of a highly respected Commercial team and support a key leader in the organization.

On-site presence in our Cambridge, MA office is typically required at least one day per week.  During busy times there may be more on-site presence required.

Responsibilities

  • Work closely and effectively with the Chief Commercial Officer, providing support in organizing meetings and calendar management, prioritizing appropriately.
  • Support other members of the Commercial department for various administrative needs across the function, including but not limited to supporting the Commercial Leadership team as we build a commercial organization in preparation for a potential launch.
  • Support commercial leadership activities by coordinating cross-functional projects, monitoring critical milestones, and facilitating communication across internal and external stakeholders.
  • Support the Commercial team with the management of POs, invoices, etc. including opening and closing POs, processing invoices, onboarding new vendors, managing vendor offboarding process.
  • Partner with other Executive Assistants to organize corporate events and meetings and Extended Leadership Team meetings. Support the Chief Commercial Officer in preparing agendas, collecting and reviewing presentation materials, reserving conference rooms and coordinating video conferences (MS Teams, Zoom, etc.).
  • Make recommendations for new ways of managing workflows and process improvements as needed.
  • Develop collaborative relationships with the Executive Assistant to the Co-CEOs, the Executive Assistant to the CFO, the Executive Assistant to the Chief Legal Officer, and the Executive Assistant to the CHRO providing back-up support as needed.
  • Coordinate domestic and international travel as well as process travel & expense reports for reimbursement.
  • Serve as a trusted business partner by proactively managing priorities, anticipating needs, and ensuring the efficient use of executive time and resources.
  • Track and coordinate key business initiatives, action items, and follow-up activities to ensure commitments are executed on time and stakeholders remain informed.
  • Handle highly confidential and sensitive information with discretion while exercising sound judgment in managing executive matters and escalating issues as appropriate.

Requirements

  • 8+ years of experience supporting C-Level executives.
  • Bachelor’s Degree and Legal experience a plus but not required.
  • Excellent organizational and prioritization abilities with meticulous attention to detail.
  • Strong interpersonal and communication skills with the ability to build and nurture relationships with stakeholders, including employees at all levels, executives, and board members.
  • Incredibly proactive; able to anticipate needs and prioritize day to day work and projects based on the demands of the business.
  • Anticipate and resolve issues.
  • Proven time management skills with the ability to handle multiple tasks, execute effectively against multiple projects and deadlines, and remain cool under pressure.
  • Demonstrated ability to operate independently, use sound judgement and professionalism.
  • Applies confidentiality and accuracy to work and interactions with employees and external partners.
  • Demonstrated proactive approaches to problem-solving,
  • Resourceful team player, with the ability to also be extremely effective independently.
  • Highly proficient in Microsoft Office Suite and an ability to learn additional project management and collaboration tools.
  • Contracts Management Systems experience preferred.
  • Able to work cross-functionally in a matrix environment.

Work Location and Conditions

  • At Amylyx, we proudly support remote work opportunities within the United States. However, due to business considerations you will be required to be onsite in our Cambridge, MA office frequently.
  • You must have access to work in setting which enables meeting all requirements of the role (including privacy, reliable internet access, phone, ability to video conference, etc.) at your remote location.

Compensation

The pay range posted below represents our good faith estimate of compensation for this role, based on market data and internal benchmarks. The final offer may vary depending on a candidate’s experience, skills, and qualifications, as well as considerations of internal equity.

Estimated Pay Range

$120,000—$135,000 USD

To stay connected with us, follow Amylyx Pharmaceuticals on LinkedIn.

To return to our website please click here.

Amylyx Pharmaceuticals is an Equal Opportunity Employer that does not discriminate on the basis of actual or perceived race, color, creed, religion, national origin, ancestry, citizenship status, age, sex or gender (including pregnancy, childbirth, pregnancy-related conditions, and lactation), gender identity or expression (including transgender status), sexual orientation, marital status, military service and veteran status, physical or mental disability, genetic information, or any other characteristic protected by applicable federal, state, or local laws and ordinances. Amylyx’s management team is dedicated to this policy with respect to recruitment, hiring, placement, promotion, transfer, training, compensation, benefits, employee activities, access to facilities and programs, and general treatment during employment. Accommodations are available for candidates who require them in our selection process. If you need an accommodation, please let your Amylyx Talent Acquisition contact know.

It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.

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