{"id":2688885,"url":"https://alion.io/job/arup-laboratories-clinical-variant-scientist-i","title":"Clinical Variant Scientist I","company":{"id":2056619,"name":"ARUP Laboratories","domain":"aruplab.com","url":"https://alion.io/company/aruplab","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":null,"truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"inferred_company_offices","remote_working_hours":null,"hiring_geo_confidence":"inferred","locations":[],"countries":[],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":79601,"max":119433,"currency":"USD","period":"year","gross":null,"usd_annual":119433},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-10-16T06:40:36Z","employer_posted_date":null,"last_verified_at":"2026-10-16T06:40:36Z","board_verified":false,"closed_at":null,"days_open":20,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":20},"description":"Schedule:\nMonday - Friday (40 hrs/wk)\n8:00 AM - 5:00 PMDepartment: Genomics Analysis - 396\n***Exact compensation will vary based on skills and experience.***\nPrimary Purpose:\nThe Clinical Variant Scientist is responsible for the interpretation and classification of genetic variants identified through clinical testing, ensuring accurate and clinically relevant reporting. This role involves reviewing genomic data, applying established guidelines (e.g. ACMG, AMP, ClinGen), and integrating evidence from scientific literature, databases, and internal resources. The scientist collaborates with laboratory teams, genetic counselors, and medical directors to provide high-quality variant assessments and reports that support patient care. Additional responsibilities include maintaining up-to-date knowledge of genomic research and guidelines, contributing to quality assurance processes, and assisting in the development of standard operating procedures and best practices for variant interpretation. This position requires that roughly 85-95% of time is spent on analysis of clinical cases, with the remainder of time spent on other duties. This position demands focused individuals with attention to detail and strong critical thinking skills.\nThis is a fully remote position and will be focused on analysis of Oncology NGS tests and somatic variant interpretation.\nAbout ARUP:\nARUP Laboratories is a national clinical and anatomic pathology reference laboratory and an enterprise of the University of Utah and its Department of Pathology. Based in Salt Lake City, Utah.\nARUP proudly hires top talent to create a work environment of diversity, professional growth and continuous development. Our workforce is committed to the important service we provide to over one million patients each month. We always strive for excellence and have a strong desire to have involvement with the advances in medicine and the role laboratory services plays within each patient’s life. We never forget that there is a patient behind every specimen we receive.\nWe are looking for individuals who want to contribute to ARUP's culture of accountability, integrity, service, and excellence. Consider joining our dynamic team.\"\nEssential Functions:\nPerform either somatic or germline variant interpretation using standard nomenclature and professional standard classification guidelines (e.g. ACMG, AMP, ClinGen).\nEvaluate quality of data produced from clinical laboratory testing, primarily from next generation sequencing/massively parallel sequencing (NGS/MPS) platforms.\nResearch and determine clinical significance of variants based on medical literature, external databases, and computational prediction software. \nUnderstand basic concepts in protein structure and function, RNA splicing, and gene regulation, and how these relate to genetic mechanisms of disease and sequence variants observed in a given specimen. \nUnderstand experimental methods, data analysis methods, and inferences that can be applied to both single-gene experimentation and high-throughput analyses.\nCollect and integrate data from multiple sources within the context of cancer biology and/or heritable disorders, and the potential impact on clinical care. \nPerform data entry with high accuracy and be able to recognize inconsistencies and initiate resolution.\nAssess the plausibility of laboratory results through correlation of data with patient demographics and clinical symptoms.\nDraft clinical reports with accuracy and consistency for review by medical directors.\nWork effectively with other scientists, staff, directors, and management to troubleshoot unique scenarios, identify areas to optimize and improve processes, and implement changes in clinical workflows. \nMaintain continual compliance with policies, procedures, and record keeping necessary to meet the standards of regulatory agencies.\nAccept, resolve, and assist in the resolution of problems. \nPerform assessment of peers performing non-waived testing as a Qualified Observer after two years’ experience.\nFlexible schedule determined by operational needs and may include occasional weekends to meet clinical reporting requirements.\nOther duties as assigned.Physical and Other Requirements:\nStooping: Bending body downward and forward by bending spine at the waist.\nReaching: Extending hand(s) and arm(s) in any direction.\nMobility: The person in this position needs to occasionally move between work sites and inside the office to access file cabinets, office machinery, etc.\nCommunicate: Frequently and effectively communicates with others.\nPPE: Biohazard laboratory environment that requires use of personal protective equipment in accordance with CDC and OSHA regulations and company policies.\nARUP Policies and Procedures: To conduct self in compliance with all ARUP Policies and Procedures.\nSedentary Work: Exerting up to 10 pounds of force occasionally and/or negligible amount of force frequently or constantly to lift, carry, push, pull or otherwise move objects.\nFine Motor Control: Picking, pinching, typing or otherwise working, primarily with fingers rather than with the whole hand as in handling.\nVision: Having close, far, and peripheral visual acuity to perform a variety of tasks such as make general observations of depth and distance.\nColor Vision: Perception of and ability to distinguish colors.\nOriginally posted on Himalayas","description_format":"text","description_chars":5381,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Flexible schedule"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Education","Health Care","Professional Services"],"lifecycle":[{"event":"open","at":"2026-10-16T08:28:30Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 93 · green card filings: 93","filings_12m":93,"filings_prev_12m":127,"green_card_filings_12m":93,"median_offered_wage_usd":72500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":53,"band":"ok","label":"Likely open","p_open":0.85,"p_active":0.829,"p_room":0.75,"age_days":19,"expected_fill_days":26,"reasons":["seen:19","win:late","comp:junior"],"computed_at":"2026-11-05T05:54:30Z"},"pay":{"stated_usd_annual":119433,"is_top_pay":true},"html_url":"https://alion.io/job/arup-laboratories-clinical-variant-scientist-i","json_url":"https://alion.io/job/arup-laboratories-clinical-variant-scientist-i.json","meta":{"generated_at":"2026-11-06T02:40:59Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":4631,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-07T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2056619},"rest":"https://alion.io/mcp/rest/get_company?id=2056619"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Farup-laboratories-clinical-variant-scientist-i"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Farup-laboratories-clinical-variant-scientist-i"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Farup-laboratories-clinical-variant-scientist-i"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/arup-laboratories-clinical-variant-scientist-i\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Farup-laboratories-clinical-variant-scientist-i"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":2688885}},{"tool":"search_jobs","arguments":{"company":"aruplab.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":2688885},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}