{"id":414528,"url":"https://alion.io/job/ascendispharma-associate-director-program-safety-lead-job-id-1908b","title":"Associate Director, Program Safety Lead","company":{"id":8553,"name":"Ascendis Pharma","domain":"ascendispharma.com","url":"https://alion.io/company/ascendispharma","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workable","truth_index":{"grade":"A","score":96,"open_postings":13,"ghost_share":0,"stale_share":0.154,"repost_share":0,"time_to_fill_p50_days":58,"computed_at":"2026-10-31T05:58:55Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"head","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Palo Alto, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":200000,"max":215000,"currency":"USD","period":"year","gross":null,"usd_annual":215000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-07-24T00:00:00Z","employer_posted_date":"2026-07-24","last_verified_at":"2026-10-31T21:48:18Z","board_verified":true,"closed_at":null,"days_open":99,"trust":{"level":"ok","repost_count":0,"flags":[],"days_open":99},"description":"Are you passionate about patient safety and ready to help lead a fast-paced, global pharmacovigilance organization? Ascendis Pharma is seeking an experienced Program Safety Lead to champion safety excellence, drive compliance, and shape strategy across our growing portfolio.\nWe are a dynamic, global biopharmaceutical company headquartered in Denmark with hubs in Palo Alto, CA and Princeton, NJ. Come join us at Ascendis Pharma, where our core values --- Patients, Science & Passion, drive us to deliver best-in-class therapies that address critical unmet needs.\nThe role\nThe role of Program Safety Lead is an associate director level position here at Ascendis and this Lead will report to the Head of Global Medical Safety Science. You will play a pivotal role as the Program Safety Lead and pharmacovigilance expert for the Ascendis’ endocrinology pipeline. As a key member of the Global Patient Safety Organization and cross-functional product teams, you will shape the strategy, set priorities and lead pharmacovigilance activities for assigned products. The Program Safety Lead stewards the product safety profile and drives critical safety-related decisions to support the Ascendis portfolio.\nAs a member of our global team, you will work with highly skilled and passionate colleagues to advance our exciting product pipeline.\nYou will:\nDefine safety strategy for assigned development and marketed products in collaboration with cross-functional teams \nServe as the safety lead for assigned products, providing strategic recommendations and oversight of patient safety activities \nEnsure compliance with global pharmacovigilance regulations, including signal detection, evaluation, and risk management \nDevelop and maintain safety surveillance and risk management plans for drug development programs \nOversee identification and evaluation of safety signals and ensure timely escalation and resolution \nProvide medical and safety input for expedited and aggregate safety reports (e.g., SUSARs, PSURs, DSURs, IND Annual Reports) \nContribute to safety sections of labeling, investigator brochures, protocols, informed consent forms, and regulatory submissions \nCollaborate with internal and external stakeholders on pharmacovigilance agreements, audits, and regulatory inspections \nMonitor industry best practices and evolving global safety regulations; recommend updates to policies and SOPs \nAct as a patient safety advisor across Clinical Development, Medical Affairs, Commercial, and PV teams\nThe estimated salary range for this position is $200-215k DOE. Actual salary determination is dependent on a variety of factors some of which include: experience, qualifications, and geographic location. This position may be eligible for a discretionary annual bonus or an incentive compensation plan (eligibility varies based on role and position level), discretionary stock-based long-term incentives, paid time off, and a comprehensive benefits package.\nRequirements\nYour professional qualifications\nYou have a PharmD degree- and are proficient in English at a professional level, both written and spoken.\nFurthermore, you have:\n6-8 years, of industry pharmacovigilance experience in a fast-paced biopharmaceutical company. \nLeadership experience within the safety profile of products assigned within a matrix organization \nEndocrinology Therapeutic Area experience \nDemonstrated skills in clinical medicine with at least 1 year of clinical practice experience is preferred \nAs a person, you have/are:\nA passion for advancing innovative therapies that address unmet medical needs for patients struggling with Rare Endocrine Diseases\nComfortable balancing strategic thinking with hands-on execution and mentoring \nDemonstrated ability to navigate uncertainty and adapt quickly to changing priorities \nProven track record delivering results in dynamic, fast-paced settings where clarity evolves over time \nTravel: Ability to travel up to 20% of the time domestically and internationally\nOffice location: This is a hybrid role operating preferably out of Palo Alto, CA; however, we welcome candidates to apply residing near our Princeton, NJ office.\nBenefits\n 401(k) plan with company match \n Medical, dental, and vision plans \n Company-offered Life and Accidental Death & Dismemberment (AD&D) insurance \n Company-provided short and long-term disability benefits \n Unique offerings of Pet Insurance and Legal Insurance\n Employee Assistance Program\n Employee Discounts\n Professional Development\n Health Saving Account (HSA)\n Flexible Spending Accounts\n Various incentive compensation plans\n Accident, Critical Illness, and Hospital Indemnity Insurance \n Mental Health resources \n Paid leave benefits for new parents \n A note to recruiters:\nWe do not allow external search party solicitation. Presentation of candidates without written permission from the Ascendis Pharma Inc Human Resources team (specifically from: Talent Acquisition Partner or Human Resources Director) is not allowed. If this occurs your ownership of these candidates will not be acknowledged.","description_format":"text","description_chars":5064,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"Advanced (C1)","optional":false}]},"benefits":["Professional development"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Rare Disease Therapeutics"],"lifecycle":[{"event":"open","at":"2026-09-06T02:44:41Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 1 · green card filings: 1","filings_12m":1,"filings_prev_12m":1,"green_card_filings_12m":1,"median_offered_wage_usd":172500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":28,"band":"fade","label":"Fading","p_open":1,"p_active":0.767,"p_room":0.36,"age_days":99,"expected_fill_days":58,"reasons":["conf:2","velocity","win:tail","crowd:"],"computed_at":"2026-10-31T05:58:55Z"},"pay":{"stated_usd_annual":215000,"is_top_pay":true},"html_url":"https://alion.io/job/ascendispharma-associate-director-program-safety-lead-job-id-1908b","json_url":"https://alion.io/job/ascendispharma-associate-director-program-safety-lead-job-id-1908b.json","meta":{"generated_at":"2026-10-31T22:39:15Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":35345,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-01T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":8553},"rest":"https://alion.io/mcp/rest/get_company?id=8553"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fascendispharma-associate-director-program-safety-lead-job-id-1908b"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fascendispharma-associate-director-program-safety-lead-job-id-1908b"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fascendispharma-associate-director-program-safety-lead-job-id-1908b"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/ascendispharma-associate-director-program-safety-lead-job-id-1908b\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fascendispharma-associate-director-program-safety-lead-job-id-1908b"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":414528}},{"tool":"search_jobs","arguments":{"company":"ascendispharma.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":414528},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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