{"id":2875639,"url":"https://alion.io/job/astellas-mes-application-engineer","title":"MES Application Engineer","company":{"id":703794,"name":"Astellas","domain":"astellas.com","url":"https://alion.io/company/astellas-2","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"SuccessFactors","truth_index":null},"role":"Enterprise Apps","role_family":"Enterprise Apps","seniority":null,"employment_type":null,"work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Ireland"],"countries":["IE"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-10-19T21:21:24Z","employer_posted_date":"2026-10-19","last_verified_at":"2026-10-26T09:51:16Z","board_verified":true,"closed_at":null,"days_open":6,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":6},"description":"About Astellas\nAstellas is a global life sciences company committed to turning innovative science into VALUE for patients. We provide transformative therapies in disease areas that include oncology, ophthalmology, urology, immunology and women's health. Through our research and development programs, we are pioneering new healthcare solutions for diseases with high unmet medical need. Learn more at Astellas.com.\nAre you driven to make a real difference in the lives of patients?\nWe're seeking passionate individuals who thrive in dynamic environments, embrace new ideas, and aren't afraid to take intelligent risks. People who act with unwavering integrity and are deeply committed to making a tangible impact.\nWorking Environment and Location\nThis position is Hybrid from the Killorglin, County Kerry facility. \nAt Astellas we recognize the importance of work/life balance, and we are proud to offer a hybrid working solution allowing time to connect with colleagues at the office with the flexibility to also work from home. We believe this will optimize the most productive work environment for all employees to succeed and deliver. Hybrid work from certain locations may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines.\nWorking Hours\nThis is a permanent, full-time position.\nPurpose and Scope\nThe MES Application Engineer is responsible for the functional management, change management and partly technical management of the business application for Pas-X MES from Korber. Also, will work closely with Pas-X project rollout team to other areas.\nRole and Responsibilities\nKey point of contact with the Business Units where Pas-X MES is implemented.\nProvides support to the key users (KU) by co-coordinating change requests; issue resolution and training support as required.\neMBR design and modeling.\nSet up and maintain all User access profiles and security requirements. Perform periodic reviews of user access, audit trails, system as required.\nKey point of contact to Korber and other 3rd party support vendors.\nEnsure the application is maintained in a validated state as per GAMP requirements and performs to an agreed performance level.\nThe MES Application Engineer is a key Subject Matter Expert (SME) for Internal and External audits.\nMaintain and understand the Astellas system in relation to the interfaces with other applications and equipment.\nDevelop project plans for small projects or work closely with PTG for major upgrades.\nSupport KU with definition of User Requirement Specification (URS), business case and risk assessment.\nEnsure all changes are adequately tested as per approved procedures.\nInvestigate opportunities for process optimisations, without introducing customisations within the system.\nCo-ordination of new Astellas and supplier releases.\nApplication configuration management.\nChange management.\nSolve incidents and problems in conjunction with 3rd party solution providers and maintain FAQ.\nReporting various KPI’s (incidents, problems, changes, small projects) to management where applicable.\nSupport of other applications and/or automated systems where necessary.\nMaintaining Pas-X MES relevant standard operating procedures.\nOn call support may be required as time to support manufacturing.\nEssential Qualifications\nDegree in IT, Engineering or a Science related discipline or relevant 3rd level qualification with appropriate experience.\nPreferred Qualifications\nPharmaceutical experience. Experience with MES systems is highly desirable.\nBenefits\nCareers | Astellas\nWhy Astellas\nGlobal collaboration: Become part of a connected global business of like-minded life science leaders, all dedicated to improving patients' lives worldwide. \nReal-world patient impact: Contribute to transformative therapies that reach patients around the world, knowing your work makes a difference every day.\nRelentless Innovation: Join a company at the forefront of scientific breakthroughs, where you'll have the opportunity to shape the future of healthcare.\nA Culture of Growth: Chart your own course within a supportive environment that values your contributions, champions your development, and empowers you to pursue your passions.\nOur Organisational Values and Behaviours\nIntegrity\nInnovation\nImpact\nOne Astellas\nAccountability\nCourage\nSense of Urgency\nOutcome Focus\nSkills and Capabilities\nOrganizational Focus\n.\nWe are an equal opportunity employer, and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.\nBeware of recruitment scams impersonating Astellas recruiters or representatives. Authentic communication will only originate from an official Astellas LinkedIn profile or a verified company email address. 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