{"id":1968951,"url":"https://alion.io/job/astrazeneca-principal-engineer-hvac-clean-utilities-process","title":"Principal Engineer – HVAC, Clean Utilities & Process","company":{"id":13195,"name":"AstraZeneca","domain":"astrazeneca.com","url":"https://alion.io/company/astra-zeneca","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":94,"open_postings":172,"ghost_share":0.012,"stale_share":0.366,"repost_share":0.105,"time_to_fill_p50_days":19,"computed_at":"2026-11-10T06:52:35Z"}},"role":"Hardware","role_family":"Hardware","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Frederick, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":146721,"max":220082,"currency":"USD","period":"year","gross":null,"usd_annual":220082},"salary_estimate":null,"experience_years_min":10,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Bioreactors","optional":false},{"name":"CAPA","optional":false},{"name":"GMP","optional":false},{"name":"Microsoft Office","optional":false},{"name":"SharePoint","optional":false}],"status":"live","first_seen_at":"2026-10-06T18:27:22Z","employer_posted_date":"2026-10-27","last_verified_at":"2026-11-10T04:28:09Z","board_verified":true,"closed_at":null,"days_open":34,"trust":{"level":"ok","repost_count":1,"flags":[],"days_open":34},"description":"Principal Engineer - HVAC, Clean Utilities & Process\n\n Our Frederick Manufacturing Center (FMC) creates life-changing medicines for people around the world and has been recognized by our local community as being a Top 50’ Business in Frederick and awarded Frederick County’s ‘Best Place to Work’. This distinctive biologic manufacturing facility, with over 800 employees, plays a direct role in treating patients with cancer, respiratory diseases, and autoimmune conditions globally.\nAt FMC, we are committed to delivering life-changing medicines while also creating a workplace where people feel valued and connected. From catered site events and friendly competitions to community outreach, environmental and wellness programs, and team-building activities, we make time to celebrate achievements and recognize the diversity of our workforce. We are dedicated to fostering a culture of inclusion, collaboration, and continuous learning through ongoing skill development and training opportunities for our employees.\nDriven by our ambition to accelerate growth, improve patients’ lives, and shape the future of AstraZeneca Operations, there has never been a more exciting time to join our team.\nPosition Summary\nThe Principal Engineer - HVAC, Clean Utilities & Process serves as a site-wide technical expert and subject-matter expert for GMP HVAC systems, clean utilities, manufacturing systems, and process engineering. This role provides technical leadership across strategic and complex capital projects, operational initiatives, quality investigations, risk management activities, and asset life-cycle assessments.\nThe Principal Engineer works independently within a matrix organization to develop and implement robust engineering solutions that support safe, compliant, reliable, and efficient biologics manufacturing operations. The role also provides coaching and technical development for engineers, technicians, interns, and contractors while supporting departmental objectives and continuous improvement.\nKey Responsibilities\nTechnical Leadership and Subject-Matter Expertise\nServe as the recognized technical expert for HVAC, clean utilities, process systems, and related manufacturing systems across the site, including buildings, internal systems, and external infrastructure.\nProvide subject-matter expertise in clean utility systems, including Water for Injection (WFI), pure steam, OFCA, and specialty gases.\nProvide subject-matter expertise in GMP HVAC systems, cleanroom design, cleanroom operation, environmental control, and associated compliance requirements.\nApply advanced knowledge of commercial biologics manufacturing operations, including bioreactors, centrifuges, formulation, column packing, utilities, automated systems, equipment, and general site operations.\nServe as a technical expert and engineering representative on large capital projects from the concept and design phases through execution, commissioning, qualification, and operational readiness.\nLead or advise on strategic, complex, and cross-functional projects and initiatives.\nDevelop departmental engineering tools, standards, training materials, and technical guidance.\nMaintain and expand technical expertise through continuous learning, professional development, industry networking, and engagement with external partners and professional organizations.\nQuality, Compliance, and Risk Management\nLead investigations into major deviations and complex technical, quality, and safety-related issues.\nOwn quality records within assigned areas of expertise and ensure timely, compliant, and technically sound resolution.\nServe as a subject-matter expert for risk management, including the identification, evaluation, mitigation, and communication of site-wide risks.\nSupport Asset Life-Cycle Management assessments by evaluating equipment condition, criticality, reliability, obsolescence, and future investment needs.\nProvide technical support to Safety, Health, and Environment (SHE) teams regarding system excursions, potential regulatory or safety observations, and potential Notices of Violation (NOVs).\nAct as an audit subject-matter expert across multiple engineering, utility, HVAC, process, and manufacturing systems.\nPartner with Quality and Safety functions to address observations, implement improvements, and share organizational learnings.\nEnsure engineering solutions and project execution comply with applicable GMP, safety, quality, regulatory, and company requirements.\nContinuous Improvement and Operational Excellence\nAct as a role model for advancing Lean principles, including continuous improvement, standard work, and layered audits.\nIdentify opportunities to improve system reliability, operational performance, compliance, efficiency, and cost effectiveness.\nChampion the sharing and adoption of engineering best practices across departments, functions, and sites.\nUse experience and technical insight to anticipate risks, prevent recurrence, and influence the implementation of sustainable corrective and preventive actions.\nSupport the development of a learning organization by communicating lessons learned, best practices, and effective problem-solving approaches.\nProblem Solving and Decision-Making\nLead or participate in complex problem-solving teams involving technical, quality, safety, operational, and business challenges.\nUse extensive experience to anticipate problems and risks and develop effective mitigation and contingency strategies.\nIdentify cross-functional and site-wide risks and recommend appropriate corrective actions, controls, and escalation pathways.\nUse stakeholder networks and organizational influence to resolve problems at both the operational and strategic levels.\nEncourage creativity, collaboration, and diverse perspectives within cross-functional problem-solving teams.\nDemonstrate sound judgment, composure, and independence when managing challenges, conflicts, opportunities, and critical issues.\nCoach and mentor team members in structured problem-solving, root-cause analysis, and corrective action development.\nProject and Business Execution\nEnsure projects and initiatives are delivered in accordance with approved scope, schedule, budget, quality, safety, and compliance requirements.\nUnderstand dependencies between strategic projects and coordinate activities to maintain progress and minimize business disruption.\nDevelop engineering solutions that address business challenges and support site strategy and objectives.\nIdentify and remove cross-functional obstacles that may prevent achievement of business goals.\nDefine and prioritize personal and team workloads in alignment with strategic imperatives and departmental priorities.\nWork effectively within a matrix organization and maintain clear communication with project sponsors, stakeholders, functional leaders, and site partners.\nSupport the Engineering Director with engineering zero-based budgeting, resource planning, and workload assessments.\nContribute to the development and delivery of departmental goals, objectives, and annual operating plans.\nCoaching, Training, and Leadership\nProvide direct coaching, technical guidance, and supervision to engineers, interns, contractors, and technicians as assigned.\nSet priorities, expectations, and development goals for team members and project contributors.\nDevelop and deliver departmental training, technical curricula, and training materials.\nAssess and coach engineers through skills-matrix courses and technical development programs.\nEstablish an environment that encourages open dialogue, collaboration, inclusion, and diversity of thought.\nPromote high performance through effective communication, coaching, influence, and constructive feedback.\nIdentify themes from feedback and use them to improve personal effectiveness and coach others.\nStakeholder and Communication Management\nServe as a trusted advisor to staff, management, customers, and project teams on complex technical matters.\nBuild and maintain productive relationships with internal stakeholders, external partners, consultants, alliances, professional organizations, and industry networks.\nWork cross-functionally to establish and improve business processes, service-level agreements, and customer-facing engineering services.\nConsistently manage stakeholders within a matrix environment through effective project and departmental forums.\nCommunicate technical information, risks, gaps, decisions, and recommendations clearly across functions and organizational levels.\nDevelop appropriate communication messages, techniques, and tools to address technical or capability gaps.\nDemonstrate excellent written, verbal, listening, presentation, negotiation, and influencing skills.\nSupport effective communication across the engineering department and the broader site.\nRequired Qualifications and Experience\nBachelor’s degree in Engineering -including Electrical, Chemical, Mechanical, Computer Engineering, or a related discipline.\nAt least 10 years of experience developing, designing, commissioning, troubleshooting, and supporting industrial control systems, with significant experience developing systems from the concept phase.\nDemonstrated subject-matter expertise in clean utility systems, including WFI, pure steam, OFCA, and specialty gases.\nDemonstrated subject-matter expertise in GMP HVAC systems and cleanroom design and operation.\nSignificant experience serving as a technical subject-matter expert for utilities, HVAC, process systems, and manufacturing systems on large capital projects.\nAdvanced knowledge of commercial biologics manufacturing operations, including bioreactors, centrifuges, formulation, column packing, utilities, and automated manufacturing systems.\nExperience supporting regulated manufacturing environments and working in accordance with applicable GMP, quality, safety, and regulatory requirements.\nExperience leading complex technical investigations, risk assessments, corrective actions, and cross-functional improvement initiatives.\nExperience coaching, mentoring, and developing engineers and technical personnel.\nKnowledge and Competencies\nExpert knowledge of site-wide manufacturing processes, utilities, HVAC, automated systems, equipment, and general operations.\nStrong understanding of engineering project execution, including design development, technical review, scope management, cost, schedule, commissioning, qualification, and operational handover.\nAbility to apply technical knowledge to influence departmental objectives, strategic initiatives, capital projects, and operational decisions.\nAbility to independently define priorities, manage competing demands, and deliver results with limited direction.\nAbility to understand business and site objectives and translate them into effective engineering strategies and deliverables.\nDemonstrated ability to work across multiple organizational levels and functions in a matrix environment.\nStrong risk-based decision-making, stakeholder management, facilitation, negotiation, and influencing skills.\nBroad recognition as an engineering and project management expert who consistently delivers high-quality assignments.\nCommitment to safety, quality, compliance, continuous improvement, and best-practice sharing.\nSystems and Technical Tools\nProficient computer skills, including Microsoft Office applications.\nExperience with relevant engineering, manufacturing, quality, and enterprise systems, such as:SAP\nTrackWise/EQV\nCAD applications\nDocument management systems\nSharePoint\n Regulatory systems, including Angel\n\nThe annual base pay for this position ranges from $146,721.60 - $220,082.40 USD Annual. Base pay offered may vary depending on multiple individualized factors, including market location, job-related knowledge, skills, and experience. In addition, our positions offer a short-term incentive bonus opportunity; eligibility to participate in our equity-based long-term incentive program (salaried roles), to receive a retirement contribu...","description_format":"text","description_chars":13243,"description_truncated":true,"requirements":{"experience_years_min":10,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Continuous learning","Equity","Professional development","Retirement plans","Wellness"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["HVAC & Refrigeration","Oncology Therapeutics","Rare Disease Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"reopen","at":"2026-10-27T19:35:23Z"}],"visa":[],"liveness":{"score":31,"band":"fade","label":"Fading","p_open":1,"p_active":0.694,"p_room":0.45,"age_days":34,"expected_fill_days":19,"reasons":["conf:2","velocity","win:tail","comp:brand"],"computed_at":"2026-11-10T06:52:35Z"},"pay":{"stated_usd_annual":220082,"is_top_pay":false},"html_url":"https://alion.io/job/astrazeneca-principal-engineer-hvac-clean-utilities-process","json_url":"https://alion.io/job/astrazeneca-principal-engineer-hvac-clean-utilities-process.json","meta":{"generated_at":"2026-11-10T07:14:49Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":16847,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-11T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":13195},"rest":"https://alion.io/mcp/rest/get_company?id=13195"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fastrazeneca-principal-engineer-hvac-clean-utilities-process"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fastrazeneca-principal-engineer-hvac-clean-utilities-process"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fastrazeneca-principal-engineer-hvac-clean-utilities-process"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/astrazeneca-principal-engineer-hvac-clean-utilities-process\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fastrazeneca-principal-engineer-hvac-clean-utilities-process"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":1968951}},{"tool":"search_jobs","arguments":{"company":"astrazeneca.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":1968951},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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