{"id":406931,"url":"https://alion.io/job/astrazeneca-senior-global-development-medical-director","title":"Senior Global Development Medical Director","company":{"id":13195,"name":"AstraZeneca","domain":"astrazeneca.com","url":"https://alion.io/company/astra-zeneca","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":91,"open_postings":132,"ghost_share":0.008,"stale_share":0.47,"repost_share":0.106,"time_to_fill_p50_days":20,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"head","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Gaithersburg, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":288059,"max":432088,"currency":"USD","period":"year","gross":null,"usd_annual":432088},"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GCP","optional":false}],"status":"live","first_seen_at":"2026-08-26T00:00:00Z","employer_posted_date":"2026-08-26","last_verified_at":"2026-11-03T01:06:34Z","board_verified":true,"closed_at":null,"days_open":69,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":69},"description":"Senior Global Development Medical Director\nAstraZeneca is seeking a Senior Global Development Medical Director to provide clinical and scientific leadership across global development programs in Cardiovascular, Renal and Metabolic Diseases (CVRM).\nAs a Research Physician or Scientist, you will work within cross-functional global teams to design, conduct, interpret, and report clinical studies. You will collaborate with the Global Clinical Head, regulatory agencies, external medical experts, alliance partners, investigators, and internal stakeholders to advance medicines through development and toward patients.\nThe role also includes contributing to publications and congress presentations, providing medical input into core labelling texts, supporting commercial activities, and contributing scientific expertise to pricing and value strategies.\nKey responsibilities\nMedical and scientific leadership\nProvide strategic medical and scientific expertise throughout the design, initiation, execution, completion, and interpretation of clinical studies.\nLead study design concepts and establish clear objectives for clinical programs and individual studies.\nProvide medical expertise with Product Teams and support interpretation of clinical and safety data.\nDeliver medical information and responses to regulatory authorities, ethics committees, investigators, study sites, and Marketing Companies.\nMaintain current knowledge of relevant literature, treatment guidelines, and emerging medical developments.\nClinical trial delivery and safety\nProvide medical accountability to the Global Clinical Head for assigned studies.\nDrive medical decisions within the Study Team and resolve clinical issues.\nEnsure studies meet the highest ethical, safety, GCP, regulatory, and AstraZeneca standards.\nProvide medical input into protocols, statistical analysis plans, amendments, informed consent forms, case report forms, safety plans, and risk-based monitoring plans.\nOversee study-level safety surveillance, including adverse events and serious adverse event reporting, data queries, blinded safety review, and escalation of emerging concerns.\nSupport international investigator meetings and national activities.\nPrepare and approve Clinical Study Reports with the Global Clinical Head, including the Introduction, Results, and Discussion sections.\nIdentify study risks and propose mitigation strategies for Phase IIb, Phase III, Phase IV, and life-cycle management studies.\nEssential qualifications\nM.B.B.S., M.D., Ph.D., or equivalent medical or scientific qualification.\nAt least 5-8 years of relevant clinical development experience, including study design, protocol development, trial implementation, monitoring, data interpretation, and reporting.\nExperience in clinical development and working within cross-functional teams.\nKnowledge of biostatistics, global regulatory requirements, pharmacovigilance, GCP, and clinical trial safety.\nStrong analytical, problem-solving, teamwork, and influencing skills.\nExcellent written and verbal English communication skills.\nStrong presentation and stakeholder engagement capabilities.\nAbility to work effectively across global teams and travel as required.\nPreferred experience\nExpertise in CVRM nephrology, cardiology, cardiovascular disease, chronic kidney disease, diabetes, obesity, metabolic disease, NASH, or MASH.\nExperience with Phase IIb, Phase III, Phase IV, outcomes, or life-cycle management studies.\nUnderstanding of pharmaceutical R&D milestones and the interaction between clinical, commercial, regulatory, safety, market access, pricing, and value objectives.\nExperience with regulatory submissions, publications, congress presentations, investigator-initiated studies, or external alliance partnerships.\nExperience contributing to labelling, payer evidence, or commercial medical strategies.\nKey success factors\nScientific credibility: Applies strong clinical expertise and sound judgment.\nCollaborative leadership: Builds trust and works effectively across functions, cultures, and geographies.\nPatient focus: Prioritizes patient safety, ethical conduct, and meaningful outcomes.\nAnalytical rigor: Interprets data objectively and communicates clear, balanced conclusions.\nAgility: Responds effectively to changing scientific, operational, and regulatory needs.\nExternal influence: Builds effective relationships with regulators, investigators, medical experts, payers, and partners.\nAstraZeneca values: Demonstrates integrity, courage, curiosity, collaboration, and accountability.\nCompensation and working environment.\nThe annual base salary range is $288,059 to $432,088 annually USD, depending on factors including location, skills, experience, and qualifications. The role may also be eligible for a short-term incentive bonus and equity-based long-term incentive program, subject to applicable terms.\nAstraZeneca’s Gaithersburg site offers a collaborative and inclusive workplace, with amenities including gym access, networking events, lunch-and-learn sessions, and a sustainable office environment. Employees work from the office a minimum of three days per week, subject to role requirements and applicable arrangements.\nWhy AstraZeneca?\nAt AstraZeneca, we follow science to develop life-changing medicines. We bring diverse teams together, encourage bold thinking, and create opportunities to make a meaningful difference for patients worldwide.\nAstraZeneca is an equal opportunity employer committed to diversity, inclusion, and professional development.\nDate Posted\n26-Aug-2026Closing Date\n29-Nov-2026Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.","description_format":"text","description_chars":5991,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"Upper-Intermediate (B2)","optional":false}]},"benefits":["Equity","Professional development"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Oncology Therapeutics","Rare Disease Therapeutics","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-09-06T01:24:49Z"}],"visa":[],"liveness":{"score":25,"band":"fade","label":"Fading","p_open":1,"p_active":0.706,"p_room":0.35,"age_days":68,"expected_fill_days":20,"reasons":["conf:2","velocity","win:tail","comp:brand"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":432088,"is_top_pay":true},"html_url":"https://alion.io/job/astrazeneca-senior-global-development-medical-director","json_url":"https://alion.io/job/astrazeneca-senior-global-development-medical-director.json","meta":{"generated_at":"2026-11-03T03:20:05Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":4410,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-04T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":13195},"rest":"https://alion.io/mcp/rest/get_company?id=13195"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fastrazeneca-senior-global-development-medical-director"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fastrazeneca-senior-global-development-medical-director"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fastrazeneca-senior-global-development-medical-director"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/astrazeneca-senior-global-development-medical-director\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fastrazeneca-senior-global-development-medical-director"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":406931}},{"tool":"search_jobs","arguments":{"company":"astrazeneca.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":406931},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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