{"id":3598484,"url":"https://alion.io/job/astrix-computational-scientist","title":"Computational Scientist","company":{"id":4424988,"name":"Astrix","domain":"astrixinc.com","url":"https://alion.io/company/astrix-4","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":null,"truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":null,"employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":135000,"max":170000,"currency":"USD","period":"year","gross":null,"usd_annual":170000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Machine Learning","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"Python","optional":false}],"status":"closed","first_seen_at":"2026-11-02T03:33:31Z","employer_posted_date":null,"last_verified_at":"2026-11-02T15:28:36Z","board_verified":false,"closed_at":"2026-11-02T15:28:36Z","days_open":0,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":0},"description":"Astrix is recruiting for an unnamed life sciences technology company seeking a Computational Scientist. The role analyzes microbiome and metagenomic data, interprets biological findings, and supports AI-enabled research and computational workflow development.\n\nResponsibilities\nAnalyze large-scale shotgun metagenomic sequencing datasets to characterize microbial community composition, functional capacity, and ecological dynamics\nInvestigate relationships between microbial taxa, metabolic pathways, and biological phenotypes across diverse sample types including human, environmental, agricultural, and industrial microbiomes\nPerform comparative analyses across cohorts, interventions, timepoints, and environmental conditions to identify biologically meaningful shifts in microbial community structure and function\nEvaluate microbial signatures associated with disease states, therapeutic interventions, ecological succession, environmental perturbations, and host-microbe interactions\nInterpret microbial functional profiles, pathway enrichments, antimicrobial resistance markers, virulence factors, and other biologically relevant features derived from sequencing data\nIdentify and assess sources of contamination, batch effects, sequencing artifacts, experimental biases, and confounding variables that may impact biological conclusions\nReview and synthesize scientific literature and public datasets to validate findings and establish evidence-based biological interpretations\nAssess the strength of evidence supporting microbiome-related hypotheses and critically evaluate analytical conclusions generated from complex sequencing datasets\nContribute subject matter expertise to AI-enabled research programs by translating microbiome workflows, analytical decision-making, and biological interpretation into structured scientific processes\nCollaborate closely with computational biologists, machine learning scientists, and software engineers on projects involving biological data interpretation and scientific knowledge extraction\nSupport development and optimization of workflows for taxonomic profiling, functional annotation, metagenome assembly, strain tracking, and multi-omics integration\nGenerate clear, scientifically rigorous reports and communicate findings to both technical and non-technical stakeholders\n\nSkills\nMaster's or PhD in Microbiology, Bioinformatics, Computational Biology, Microbial Ecology, Genetics, or a related scientific discipline\n3+ years of experience working with microbiome, microbial genomics, or metagenomics datasets in academic, biotech, pharmaceutical, or industry settings\nDemonstrated expertise through publications, research projects, product development, or industry contributions\nStrong understanding of microbial ecology, microbial physiology, host-microbe interactions, and microbiome study design\nExperience analyzing next-generation sequencing datasets, including 16S and/or shotgun metagenomics approaches\nProficiency in Python, R, or similar scientific computing environments\nFamiliarity with microbial taxonomic profiling, functional annotation, pathway analysis, diversity metrics, and community-level interpretation\n\nCompany Overview\nAstrix is the global leader in delivering innovative strategies and solutions to the life sciences industry. It was founded in 1995, and is headquartered in Red Bank, New Jersey, USA, with a workforce of 501-1000 employees. Its website is http://astrixinc.com.\n\nCompany H1B Sponsorship\nAstrix has a track record of offering H1B sponsorships, with 8 in 2026, 10 in 2025, 9 in 2024, 10 in 2023, 16 in 2022, 11 in 2021. Please note that this does not guarantee sponsorship for this specific role.","description_format":"text","description_chars":3689,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Health Care","Microbiome"],"lifecycle":[{"event":"open","at":"2026-11-02T06:21:45Z"},{"event":"close","at":"2026-11-02T15:28:36Z"}],"visa":[],"liveness":null,"pay":{"stated_usd_annual":170000,"is_top_pay":true},"html_url":"https://alion.io/job/astrix-computational-scientist","json_url":"https://alion.io/job/astrix-computational-scientist.json","meta":{"generated_at":"2026-11-03T12:03:26Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":16613,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-04T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4424988},"rest":"https://alion.io/mcp/rest/get_company?id=4424988"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fastrix-computational-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fastrix-computational-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fastrix-computational-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/astrix-computational-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fastrix-computational-scientist"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3598484}},{"tool":"search_jobs","arguments":{"company":"astrixinc.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3598484},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}