{"id":779140,"url":"https://alion.io/job/autoscience-senior-staff-software-engineer","title":"Senior / Staff Software Engineer","company":{"id":669935,"name":"Autoscience","domain":"autoscience.ai","url":"https://alion.io/company/autoscience","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"B","score":75,"open_postings":4,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-11-03T05:54:40Z"}},"role":"Backend","role_family":"Backend","seniority":"staff","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["San Mateo, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":182000,"max_usd":339000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1500},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"GCP","optional":false},{"name":"LLM","optional":false},{"name":"Python","optional":false}],"status":"live","first_seen_at":"2026-03-11T19:44:38Z","employer_posted_date":"2026-03-11","last_verified_at":"2026-11-03T17:33:40Z","board_verified":true,"closed_at":null,"days_open":236,"trust":{"level":"stale","repost_count":0,"flags":["stale"],"days_open":236},"description":"Company Description\nAt Autoscience Institute, we automate AI research. Recently, we announced the first AI agent to autonomously create peer-reviewed literature (ICLR 2025) and the first AI system to win a Kaggle medal. We are passionate about pushing the boundaries of artificial intelligence and contributing to groundbreaking advancements in the field.\nRole Description\nThis is a full-time on-site role for a Senior or Staff Software Engineer (Technical Lead) located in the San Francisco Bay Area.\nIn this role, you will lead the design and development of core systems that power autonomous research agents. You’ll be responsible for building reliable backend infrastructure and production systems that support large-scale AI experimentation and research workflows.\nWe are looking for engineers who have owned complex projects end-to-end, contributed to system architecture, and helped guide small teams of engineers through delivery. You should be comfortable writing high-quality code, producing clear design documents, and making thoughtful technical decisions that shape how systems evolve over time.\nYou will work closely with both engineers and researchers to translate experimental ideas into robust production systems.\nResponsibilities\nLead the design and implementation of core backend and infrastructure systems\n\nOwn projects from architecture and design through production deployment\n\nWrite clear technical design documents and drive engineering decisions\n\nBuild and maintain 24/7 production systems supporting autonomous research agents\n\nPartner closely with research teams to productionize experimental workflows\n\nGuide and collaborate with engineers on system design and implementation\n\nImprove system reliability, scalability, and observability\n\nHelp shape the technical direction of the platform\n\nQualifications\nExperience leading complex engineering projects or technical initiatives\n\nExperience acting as a technical lead or guiding small teams of engineers\n\nStrong software design and architecture skills\n\nDemonstrable experience writing clear technical design documents\n\nStrong experience with Python\n\nExperience building or operating backend or production infrastructure\n\nExperience working in 24/7 production environments\n\nExperience with Google Cloud Platform (GCP) or similar cloud infrastructure\n\nStrong understanding of software evolution, maintainability, and system design tradeoffs\n\nAbility to collaborate effectively with both engineers and researchers\n\nBachelor’s degree in Computer Science, Mathematics, or a related field\n\nStrong candidates will typically have 5+ years of experience building and operating production software systems, including ownership of projects from design through deployment\n\nBenefits & Perks\nOur comp is competitive against major LLM frontier lab packages\n\nUnlimited PTO and flexible working arrangements\n\nConference attendance and publication support\n\nOur Culture\nWe're a team of passionate researchers and engineers working to automate scientific discovery. 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