{"id":2029723,"url":"https://alion.io/job/avid-bioservices-sr-scientist-downstream-and-biologics-formulation-development","title":"Sr. Scientist, Downstream and Biologics Formulation Development","company":{"id":3865992,"name":"Avid Bioservices","domain":"avidbio.com","url":"https://alion.io/company/avidbio","size_band":"501-1000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Jobvite","truth_index":null},"role":"Biotech","role_family":"Biotech","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Tustin, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":147200,"max":184000,"currency":"USD","period":"year","gross":null,"usd_annual":184000},"salary_estimate":null,"experience_years_min":6,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Chromatography","optional":false},{"name":"HPLC","optional":false}],"status":"live","first_seen_at":"2026-10-07T13:56:21Z","employer_posted_date":"2026-10-07","last_verified_at":"2026-10-31T04:11:26Z","board_verified":true,"closed_at":null,"days_open":23,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":23},"description":"Description\nLooking to join a passionate team dedicated to developing and manufacturing life-saving biopharmaceuticals? Avid Bioservices is a leading clinical and commercial biologics CDMO focused on creating innovative solutions to meet the needs of our clients and improve patient outcomes.\nYour Role:\nAvid is seeking a highly motivated and technically strong Sr. Scientist, Downstream and Biologics Formulation Development to lead biologics formulation development while contributing to integrated downstream process development within a fast-paced, client-facing environment. This role is responsible for defining formulation strategies, executing technical studies, and supporting cross-functional integration as the capability expands. Additional responsibilities include designing downstream purification processes for protein-based biologics, viral clearance studies, scale-down and scale-up activities, and technology transfer to manufacturing. The individual will collaborate closely with Cell Line Development, Upstream Process Development, Analytical Sciences, MSAT, DS/DP Manufacturing, Program Management, and external partners to support client programs.\nKey Responsibilities: \nLead formulation development for biologics, including pre-formulation assessments, excipient screening, and stability studies. Demonstrated experience in formulation development for complex biologic modalities-including antibody-drug conjugates (ADCs)-with understanding of modality-specific stability and developability challenges is highly advantageous.\nLead downstream process development for biologics, including capture chromatography, polishing chromatography, viral inactivation/filtration, and tangential flow filtration (TFF).\nExtensive hands-on experience with analytical techniques for protein characterization, including DLS, DSF, SEC, CE, rheology, and spectroscopy. Design and interpret analytical testing strategies including HPLC (SEC & IEX), CE-SDS, SDS-PAGE, UV spectroscopy, and other biophysical assays to support process development and formulation studies.\nExpertise in developing high concentration protein formulations and resolving issues such as aggregation, viscosity, and solubility. Able to identify and mitigate formulation risks including precipitation and chemical degradation.\nDesign experiments, analyze data, and prepare technical protocols, reports, and development summaries.\nEstablish and drive scientific strategy, workflows, and best practices for early- to late-stage biologics formulation development, with the ability to operate independently in a dynamic, fast-paced, client-facing environment with evolving priorities.\nServe as a technical subject matter expert (SME) in client engagements, including proposals, presentations, and project reviews; prior line management or informal leadership experience is advantageous.\nCollaborate effectively with cross-functional teams to align project timelines, priorities, and resource planning.\nMentor and develop junior scientists and technical staff, and support onboarding of new team members.\nEvaluate and implement new technologies and platform approaches to enhance internal capabilities and drive innovation. \nEnsure compliance with applicable quality, regulatory, and safety standards. \nPerform additional responsibilities as required to support evolving business and project needs.\nOccasional travel may be required (by land or air) to attend conferences, seminars, off-site client meetings, and marketing events as needed.\nMinimum Qualifications: \nMaster’s degree/PhD degree in Biochemistry, Chemistry, or related field and minimum 4-6 years of relevant experience and demonstrated working knowledge of scientific principles. \nPrior experience in formulation development, stability studies, and analytical characterization of biologics or strong background in biochemical and biophysical characterization of proteins with deep understanding of protein structure and function.\nExperience in development of ultra-high concentration and pre-developability assessment\nProven record of strong technical writing and communication skills. \nAbility to thrive in a dynamic, cross-functional environment.\nPreferred Qualifications: \nPh.D. in Biochemistry, Chemistry, or related field with 4-6 years of industry experience, or M.S. with 6-10 years of experience. \nPrior experience in formulations process development and/or downstream process development of biologics is a plus.\nExperience mentoring or leading scientific staff preferred. \nCandidates with strong expertise in either biologics formulation development or downstream process development will be considered, with opportunities to contribute across both areas.\nPosition Type/Expected Hours of Work:\nThis role is a full-time onsite position. Days and hours of work are Monday through Friday, 8:00am to 5:00pm PST unless otherwise stated by Supervisor. The employee must also have the ability to work overtime and/or weekends when necessary.\nCompensation:\nWe offer competitive compensation packages for this role, including a base salary, performance-based bonuses, and comprehensive benefits such as health, dental, and vision insurance, 401(k) matching, and paid time off.\nThe compensation range for this role is $147,200-$184,000 annually depending on experience and qualifications. Additionally, we offer opportunities for career growth and development as well as a supportive and inclusive work environment.\nWho you are:\nYou have a \"bring it on!\" team player approach and an unshakable positive attitude, always ready to tackle anything that comes your way.\nYour written and verbal skills are out of this world, and you communicate with clarity and confidence.\nYou have exceptional multitasking skills and an unparalleled attention to detail that ensure the smooth running of everything.\nYou are a master at building relationships, capable of establishing connections with anyone, be it team members, clients, vendors, or suppliers.\nPhysical Demands & Work Environment:\nIn this dynamic role, expect a blend of regular activities like sitting, standing, and walking, with occasional physically engaging tasks such as lifting objects up to 25 pounds. The work environment might expose you to electrical shocks, toxic chemicals, vibrations, or loud noise levels occasionally. However, reasonable accommodations are available to enable individuals with different abilities to perform effectively, ensuring a supportive and adaptable work setting. Your visual acuity, including close, distance, and color vision, will be essential in navigating through the diverse day-to-day demands of this position.","description_format":"text","description_chars":6638,"description_truncated":false,"requirements":{"experience_years_min":6,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"master","optional":true},"security_clearance":false,"languages":[]},"benefits":["Vision insurance"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biologics & Biosimilars","CRO & CDMO Services","Health Care","APIs & Drug Manufacturing"],"lifecycle":[{"event":"open","at":"2026-10-07T13:56:21Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 4 · green card filings: 1","filings_12m":4,"filings_prev_12m":2,"green_card_filings_12m":1,"median_offered_wage_usd":131500,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":35,"band":"fade","label":"Fading","p_open":1,"p_active":0.772,"p_room":0.45,"age_days":22,"expected_fill_days":13,"reasons":["conf:3","velocity","win:tail"],"computed_at":"2026-10-30T05:48:23Z"},"pay":{"stated_usd_annual":184000,"is_top_pay":true},"html_url":"https://alion.io/job/avid-bioservices-sr-scientist-downstream-and-biologics-formulation-development","json_url":"https://alion.io/job/avid-bioservices-sr-scientist-downstream-and-biologics-formulation-development.json","meta":{"generated_at":"2026-10-31T05:07:34Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":7314,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-01T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3865992},"rest":"https://alion.io/mcp/rest/get_company?id=3865992"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Favid-bioservices-sr-scientist-downstream-and-biologics-formulation-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Favid-bioservices-sr-scientist-downstream-and-biologics-formulation-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Favid-bioservices-sr-scientist-downstream-and-biologics-formulation-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/avid-bioservices-sr-scientist-downstream-and-biologics-formulation-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Favid-bioservices-sr-scientist-downstream-and-biologics-formulation-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":2029723}},{"tool":"search_jobs","arguments":{"company":"avidbio.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":2029723},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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