{"id":1743436,"url":"https://alion.io/job/basecamp-research-scientist-i-platform-innovation","title":"Scientist I, Discovery","company":{"id":47988,"name":"Basecamp Research","domain":"basecamp-research.com","url":"https://alion.io/company/basecamp-research","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"B","score":75,"open_postings":3,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-10-27T05:46:45Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"junior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Boston, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":110000,"max":140000,"currency":"USD","period":"year","gross":null,"usd_annual":140000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Anthropic","optional":false},{"name":"Basecamp","optional":false},{"name":"Cell Culture","optional":false},{"name":"Flow Cytometry","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"PCR","optional":false},{"name":"qPCR","optional":false}],"status":"live","first_seen_at":"2026-10-02T16:50:35Z","employer_posted_date":"2026-10-02","last_verified_at":"2026-10-27T13:07:48Z","board_verified":true,"closed_at":null,"days_open":24,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":24},"description":"About us\nBasecamp Research is building frontier AI for therapeutic design. We believe the future of medicine lies in reprogramming the body to repair itself, and we design the models and the medicines to teach it how.\nOur EDEN models are trained on BaseData, the world's largest proprietary genomic dataset, with over 10B genes collected through partnerships in more than 30 countries across all seven continents. This gives our AI models access to genetic diversity that doesn't exist in public databases, and enables EDEN to design cell and gene therapies, enzymes, and peptides directly from information about a disease. Our pipeline of EDEN-designed therapeutics, beginning with in vivo cell therapy, is advancing towards clinical development.\nIn September 2026 we closed an oversubscribed $140M Series C led by S32, with participation from NVIDIA, Anthropic's Anthology Fund, Catalio, European Tech Collective, Firebrand River Capital, King Philanthropies, NATO Innovation Fund, NVentures (NVIDIA's venture arm), Redalpine, Rockefeller Foundation, Singular, Sovereign AI and True Ventures. We have offices and labs in London and Boston, we partner with biopharma companies and academic institutions worldwide, and our work has been recognised by Fast Company's Top 10 Most Innovative Companies in Biotech, the FT-backed Sifted AI100 list of Europe's leading AI startups as well as Barclays Eagle Labs Ones to watch, AI100.\nAt Basecamp Research, we pride ourselves on being a lean collaborative and global team with extremely specialist and unique skills. Our biologists, engineers, ML scientists and field explorers are united by a sense of adventure and the belief that AI, biology and data, will result in new medicines for patients who have few options today.\nThe Role\nWe are seeking a highly capable and proactive Scientist I to join our Cambridge, MA team. In this role, you will leverage our proprietary biodiversity knowledge to develop transformative solutions in gene editing and cellular engineering.\nYou are an energetic and highly motivated scientist with broad experience in gene editing, NGS assay development, and protein engineering. You're comfortable with cutting-edge tools in molecular biology, cellular engineering, and high-throughput screening, with demonstrated expertise in developing and productionizing new assays. This is a collaborative position working closely with our Data Science and AI teams to tackle some of the most exciting and unique challenges in the field.\nKey Responsibilities\nContribute to new methods for discovery and engineering of novel gene editing tools. You will work closely with other team members. Responsibilities include:\nContribute to strategy for design, build, test cycles of novel protein enzymes, with a strong emphasis on discovery, validation, and engineering of novel gene editing tools;\n\nBuild and screen plasmid libraries, and develop the cloning workflows that let us do it at scale;\n\nQuantify editing outcomes using ddPCR, qPCR, flow-cytometry and NGS readouts.\n\nOptimise hits for activity and specificity using human primary cells and cell lines to develop leads for therapeutic development;\n\nContribute to an open and high-integrity scientific culture at Basecamp Research;\n\nEstablish strong documentation practices and lab SOPs as a founding member of the lab team.\n\nRequired Skills and Experience\nA PhD in molecular biology, biochemistry, genetics, bioengineering, or a life-sciences related field, or an MSc with equivalent hands-on laboratory experience.\n\nExperience with gene editing, NGS assay development, protein engineering and cell therapy;\n\nExperience with high-throughput methods of cloning and producing DNA constructs for cellular screening;\n\nExperience with mammalian cell culture, transfection, and cell-line generation;\n\nKnowledge of emerging technologies in gene editing and on/off-target analytics that enable regulatory approval;\n\nExpertise with DNA/RNA extraction, PCR, ddPCR, NGS library preparation and QC\n\nExcellent communication skills to both internal and external stakeholders\n\nAdvantageous Skills and Experience\nExperience contributing to a preclinical cell therapy program (in vivo or ex vivo);\n\nExpertise in flow cytometry using both antibody panels and fluorescent reporters;\n\nExperience developing novel methods for gene editing off-target analytics using both long and short-read sequencing;\n\nMechanistic understanding of gene editing tools, including nucleases, base editors, transposons, retrotransposons, and recombinases; Ability to reason about proteins as molecular machines;\n\nExperience integrating AI protein design tools with high-throughput wet lab screening methodologies;\n\nFluency in NGS instrumentation, basic bioinformatics tools, and traceable data pipelines.\n\nProactive Problem-Solving: A proactive, resourceful, and independent mindset. You take initiative to identify problems or inefficiencies and act on them. You’re the kind of person who spots an issue and rallies the right people to fix it before it escalates.\n\nAdaptability: Comfortable with ambiguity and rapid change. Our environment evolves quickly - you should thrive in a dynamic setting and be flexible in adjusting plans, while maintaining a positive, can-do attitude.\n\nOwnership & Drive: High degree of ownership over your work. You care about outcomes and reliably follow through on tasks and take pride in delivering quality results.\n\nWhat we offer in return\nImpactful Mission: This is a rare opportunity to do work that genuinely matters. You'll join a talented, fast-moving team, access unique biological datasets at scale, and see your contributions shape real breakthroughs in AI and curative therapeutics.\n\nCollaborative Culture: You'll be surrounded by world-class engineers, scientists, and researchers who care deeply about their work and about each other. With offices in Boston and London, we've built a flexible, cross-functional environment where personal development and real ownership aren't just talking points.\n\nHigh Growth: We truly believe in investing our top talent, we make coaching available to team members during steep growth journeys and we have twice yearly promotion opportunities. People who are really successful here own it and go directly to solve problems at pace and we ensure reward increases with impact.\n\nComprehensive Benefits: We've built a benefits package people value. That means competitive salary, equity, and healthcare so strong that most employees' family members opt into our plan over their own. We also offer Carrot Fertility with IVF stipend, 401(k), life insurance, and more.\n\nSalary range for this role is depending on skills and experience: $110K - $140K base\nApply for the job\nDo you want to join our team as our new Scientist I, Discovery? Then we'd love to hear about you!\nWe are committed to equal opportunity employment regardless of ethnic or national origin, race, religion, sex, age, citizenship, sexual orientation, marital status, disability, gender identity or any other basis. 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