{"id":513703,"url":"https://alion.io/job/basecamp-research-senior-scientist-rd","title":"Senior Scientist, R&D","company":{"id":47988,"name":"Basecamp Research","domain":"basecamp-research.com","url":"https://alion.io/company/basecamp-research","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"B","score":75,"open_postings":3,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-10-14T06:34:16Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["London, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":74000,"max_usd":127000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":14},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Anthropic","optional":false},{"name":"Basecamp","optional":false}],"status":"live","first_seen_at":"2026-08-21T16:37:34Z","employer_posted_date":"2026-08-21","last_verified_at":"2026-10-14T23:57:35Z","board_verified":true,"closed_at":null,"days_open":54,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":54},"description":"About Us\nBasecamp Research is building frontier AI for therapeutic design. We believe the future of medicine lies in reprogramming the body to repair itself, and we design the models and the medicines to teach it how.\nOur EDEN models are trained on BaseData, the world's largest proprietary genomic dataset, with over 10B genes collected through partnerships in more than 30 countries across all seven continents. This gives our AI models access to genetic diversity that doesn't exist in public databases, and enables EDEN to design cell and gene therapies, enzymes, and peptides directly from information about a disease. Our pipeline of EDEN-designed therapeutics, beginning with in vivo cell therapy, is advancing towards clinical development.\nIn September 2026 we closed an oversubscribed $140M Series C led by S32, with participation from NVIDIA, Anthropic's Anthology Fund, Catalio, European Tech Collective, Firebrand River Capital, King Philanthropies, NATO Innovation Fund, NVentures (NVIDIA's venture arm), Redalpine, Rockefeller Foundation, Singular, Sovereign AI and True Ventures. We have offices and labs in London and Boston, we partner with biopharma companies and academic institutions worldwide, and our work has been recognised by Fast Company's Top 10 Most Innovative Companies in Biotech, the FT-backed Sifted AI100 list of Europe's leading AI startups as well as Barclays Eagle Labs Ones to watch, AI100.\nAt Basecamp Research, we pride ourselves on being a lean collaborative and global team with extremely specialist and unique skills. Our biologists, engineers, ML scientists and field explorers are united by a sense of adventure and the belief that AI, biology and data, will result in new medicines for patients who have few options today.\nThe Role\nAs we continue to unlock our planet's biodiversity, we are looking for ambitious people with a passion for the development of extraction and sequencing workflows to continuously improve our data generation.\nYou will have the opportunity to help further build out our DNA / RNA pipelines to build the most diverse database in the world, with a particular focus on metagenomic recovery from challenging and varied sample types - water, soil, sediments, faeces, biofilms and beyond. You'll be comfortable with sequencing workflows from end to end, from extraction through to library preparation, and have experience with both short and long read technologies, including high molecular weight (HMW) extraction methods.\nYou'll bring real depth in metagenomic extraction methodologies and the ability to recover usable nucleic acids from difficult, low-biomass or inhibitor-rich matrices. Virology experience in both extraction and sequencing would also be beneficial to this role. You'll understand when good is good enough and can support handover for testing and implementation in production.\nYour work will contribute directly to Basecamp Research’s Trillion Gene Atlas Project, helping transform diverse global samples into high-quality biological data that can reveal new genes, proteins, pathways, and functions from nature.\nThe role is laboratory based but you will have ownership over your projects, with the opportunity to work closely with our Collaborations team who coordinate sample collection globally, and to have input into the methods for collection or extraction and the molecular biology methods that are applied to a global network of collaborators, seeing your work make an impact in real-time.\nThe role will suit someone with experience who enjoys the technically focused aspects of development, from rapid prototyping to delivery. You'll also have the opportunity to work with the Data teams, who may have specific requirements for particular targeted methods, all with the aim of increasing our database diversity, data quality and scalability. You will work in a data-first environment, using experimental and sequencing-quality metrics to guide method development, prioritisation, and handover into production.\nKey Responsibilities\nWorking with the R&D Lead, Director of Production and wider R&D and Production teams and collaborators, align R&D projects in order and prioritise during data pushes.\n\nDevelop and optimise metagenomic extraction methods across a broad range of sample types (e.g. water, soil, sediments, faeces, biofilms), including approaches for low-biomass and inhibitor-rich matrices.\n\nDevelop DNA / RNA purification methods using kits / chemistries / adaptation / in-house development to recover viruses and microbes, including high molecular weight (HMW) extractions suitable for long-read sequencing.\n\nApply and develop virology-focused workflows spanning extraction through to sequencing, recovering viral signal from complex sample backgrounds.\n\nDesign well-controlled experiments to compare extraction chemistries, sample-processing methods, library-preparation approaches, and sequencing-readout performance.\n\nDefine success criteria, generate validation data, and support the transfer of robust methods into production through clear documentation, training, and troubleshooting.\n\nPrioritise development work based on scientific value, data-generation impact, feasibility, production scalability, and organisational timelines.\n\nConfident working within a CLS 2 environment and working with genetically modified organisms and their generation.\n\nImplementation of current, or development of novel, methods for library building for Next Generation Sequencing with ownership of the projects.\n\nCapable of working within a multi-disciplinary team, both as a project lead or as part of a delivery team.\n\nCapable of analysing their own experiments and presenting this out to the wider organisation.\n\nBe a part of mentorship within the team and wider organisation.\n\nHorizon scan for emergent methodologies, either within or outside of molecular biology approaches, that could add additional value to projects.\n\nDevelop protocols for current and new NGS methods as they come in-play - lead and take charge of R&D projects that fall within this purview.\n\nWork collaboratively between other R&D sites and Data Science to understand and develop new protocols for challenging target genes / DNA modalities.\n\nRequired skills and experiences\nA minimum of 5 years' experience working on technically focused molecular biology and sequencing projects, either in a commercial R&D or large project-based academic setting for method development, ideally in non-model organisms.\n\nA strong understanding of metagenomic extraction methodologies across a range of sample types (e.g. water, soil, sediments, faeces, biofilms).\n\nExperience developing or applying high molecular weight (HMW) extraction methods.\n\nA track record in delivery of molecular methods for working with DNA and RNA, for both extraction and sequencing in end-to-end workflows.\n\nExperimental design and statistical comparison of method performance and ability to troubleshoot results.\n\nPro-active and motivated in developing new methods and tackling continuous improvement challenges.\n\nExperience working within multi-disciplinary teams to deliver projects.\n\nAdvantageous skills and experiences\nEnvironmental metagenomics or microbial ecology background.\n\nVirology experience covering both extraction and Sequencing.\n\nFamiliarity with automation and high throughput scaling of methods, its pitfalls and the development of methods for its usage.\n\nWhat we offer in return\nImpactful Mission: This is a rare chance to do work that genuinely matters. You'll join a talented, fast-moving team, access unique biological datasets at scale, and see your contributions shape real breakthroughs in AI and curative therapeutics.\nCollaborative Culture: You'll be surrounded by world-class engineers, scientists, and researchers who care deeply about their work and about each other. With offices in London and Boston, we've built a flexible, cross-functional environment where personal development and real ownership aren't just talking points.\nHigh Growth: We truly believe in investing in our people. We make coaching available to team members during steep growth journeys and we have twice-yearly promotion opportunities. People who are really successful here own it and go directly to solve problems at pace, and we ensure reward increases with impact.\nComprehensive Benefits: We've built a benefits package people value. That means competitive salary, equity, and private healthcare with no medical history exclusions - so strong that most employees' family members opt into our plan over their own. We also offer Carrot Fertility with IVF stipend, salary sacrifice pension, bike-to-work scheme, life insurance, and more.\nWe are committed to equal opportunity employment regardless of ethnic or national origin, race, religion, sex, age, citizenship, sexual orientation, marital status, disability, gender identity or any other basis. If you have a disability or additional need that needs accommodating do let us know.","description_format":"text","description_chars":8979,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity","Life insurance"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Bioinformatics","AI Training Data & Annotation","AI for Science"],"lifecycle":[{"event":"open","at":"2026-09-07T16:55:22Z"}],"visa":[{"country":"GB","licensed_sponsor":true,"evidence":"Licensed UK visa sponsor (Skilled Worker)","filings_12m":null,"filings_prev_12m":null,"green_card_filings_12m":null,"median_offered_wage_usd":null,"route":"Skilled Worker","cap_exempt":false,"checked_at":"2026-10-14T06:20:30+00:00","sources":["UK Home Office: register of licensed sponsors (workers)"],"filings_for_role_12m":0}],"liveness":{"score":33,"band":"fade","label":"Fading","p_open":1,"p_active":0.6,"p_room":0.55,"age_days":53,"expected_fill_days":38,"reasons":["conf:1","win:tail"],"computed_at":"2026-10-14T06:34:16Z"},"pay":null,"html_url":"https://alion.io/job/basecamp-research-senior-scientist-rd","json_url":"https://alion.io/job/basecamp-research-senior-scientist-rd.json","meta":{"generated_at":"2026-10-15T02:14:05Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":3213,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-16T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":47988},"rest":"https://alion.io/mcp/rest/get_company?id=47988"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fbasecamp-research-senior-scientist-rd"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fbasecamp-research-senior-scientist-rd"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fbasecamp-research-senior-scientist-rd"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/basecamp-research-senior-scientist-rd\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fbasecamp-research-senior-scientist-rd"}]}