Associate Director, Translational Medicine (Immunology)

BeOne continues to grow at a rapid pace with challenging and exciting opportunities for experienced professionals. When considering candidates, we look for scientific and business professionals who are highly motivated, collaborative, and most importantly, share our passionate interest in fighting cancer.

General Description:

BeOne continues to grow at a rapid pace, offering challenging and exciting opportunities for experienced professionals who want to make a meaningful impact. As a global, science-driven biopharmaceutical company, BeOne is committed to advancing innovative medicines through deep biological insight, rigorous translational science, and strong cross-functional collaboration. While oncology remains a core focus, BeOne is rapidly expanding its immunology and inflammation portfolio, with the goal of delivering transformative therapies for patients with serious autoimmune and immune-mediated diseases.

We are seeking a highly experienced Associate Director with a strong background in Translational Research and Translational Medicine for Immunology (Autoimmune Disease Portfolio) to join our team. The ideal candidate will bring a deep foundation in immunology, with demonstrated experience in autoimmune or immune-mediated diseases, and strong scientific insight into one or more therapeutic areas such as dermatology, rheumatology, nephrology, and/or inflammatory bowel disease (IBD).

In this role, you will serve as the clinical biomarker lead for selected immunology programs, accountable for the design and execution of mechanism-driven clinical biomarker strategies that inform patient selection, dose and regimen optimization, and key clinical decisions. You will provide translational and biomarker leadership across clinical development, contribute as a core member of development team, and help advance early- and late-stage programs through innovative biomarker and translational approaches.

Essential Functions of the Job:

• Act as the clinical biomarker lead for assigned immunology/autoimmune clinical programs and studies, serving as the primary biomarker contact for cross-functional study teams.

• Develop and implement translational and clinical biomarker strategies to support clinical development, including pharmacodynamic and mechanism-related biomarkers, dose and regimen optimization, and patient stratification; contribute to CDx strategy where appropriate.

• Interpret and communicate clinical biomarker data to support study execution and key program decisions.

• Collaborate closely with assay development, CDx, clinical operations, and analytical teams to ensure biomarker approaches are fit-for-purpose and effectively implemented in clinical studies.

• Lead biomarker-related content for clinical protocols and associated documents, in alignment with clinical objectives and regulatory expectations.

• Coordinate external vendors and partners supporting biomarker and translational activities.

• Identify translational and biomarker gaps and contribute to targeted research efforts to strengthen clinical hypotheses.

• Apply immunology and autoimmune disease expertise to guide biomarker selection and interpretation across clinical programs.

• Contribute to scientific publications and external communications in collaboration with internal stakeholders.

Qualifications and Requirements:

• Ph.D. in immunology or a related life science discipline, with 4+ years of industry experience in translational medicine, translational research, or clinical development support.

• Strong background in immunology, with experience in autoimmune or immune-mediated diseases; exposure to dermatology, rheumatology, nephrology, and/or IBD is preferred.

• Demonstrated experience applying translational approaches to inform mechanism, dose, patient selection, or clinical strategy across early and/or late-stage programs.

• Solid working knowledge of clinical biomarker science, with experience partnering with assay development and CDx teams.

• Proven ability to collaborate effectively in cross-functional, matrixed environments and with external partners.

• Strong scientific thinking, data interpretation, and communication skills.

• Ability to manage multiple priorities in a fast-paced development setting.

Computer Skills:

Proficiency with standard scientific and business software (e.g., MS Office); experience with GraphPad Prism for data visualization and figure generation; familiarity with clinical data review platforms, dashboards, and document management systems commonly used in drug development.

Travel:

Willingness to travel domestically and internationally as needed to support clinical programs, external collaborations, and scientific meetings.

Global Competencies

When we exhibit our values of Patients First, Driving Excellence, Bold Ingenuity and Collaborative Spirit, through our twelve global competencies below, we help get more affordable medicines to more patients around the world.

• Fosters Teamwork
• Provides and Solicits Honest and Actionable Feedback
• Self-Awareness
• Acts Inclusively
• Demonstrates Initiative
• Entrepreneurial Mindset
• Continuous Learning
• Embraces Change
• Results-Oriented
• Analytical Thinking/Data Analysis
• Financial Excellence
• Communicates with Clarity

BeOne is committed to fair and equitable compensation practices. Actual compensation packages are determined by several factors that are unique to each candidate, including but not limited to job-related skills, depth of experience, certifications, relevant education or training, and specific work location. Packages may vary by location due to differences in the cost of labor. The recruiter can share more about the specific salary range for a preferred location during the hiring process. Please note that the listed range reflects the base salary or hourly range only. Non-Commercial roles are eligible to participate in the annual bonus plan, and Commercial roles are eligible to participate in an incentive compensation plan. All Company employees have the opportunity to own shares of BeOne Medicines Ltd. stock because all employees are eligible for discretionary equity awards and to voluntarily participate in the Employee Stock Purchase Plan. The Company has a comprehensive benefits package that includes Medical, Dental, Vision, 401(k), FSA/HSA, Life Insurance, Paid Time Off, and Wellness.

We are proud to be an equal opportunity employer. BeOne does not discriminate on the basis of race, religion, color, sex, gender identity, sexual orientation, age, disability, national origin, veteran status or any other basis covered by appropriate law. All employment is decided on the basis of qualifications, merit, and business need. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans’ Readjustment Assistance Act of 1974, Title I of the Americans with Disabilities Act of 1990, and any other applicable federal, state or local laws, applicants who require reasonable accommodation in the job application process may contact [email protected].