Senior Associate Scientist, Gene Delivery and Editing Process Development

At Bristol Myers Squibb, our employees often ask, “Who are you working for?”-a question that fuels collaboration, accountability, and urgency in our work. Our purpose-driven culture inspires us to discover, develop, and deliver innovative medicines to prevail over serious diseases. We offer uniquely interesting and meaningful work, opportunities for growth, and a supportive environment that values inclusion, wellbeing, flexibility, and comprehensive benefits. This is work that transforms the lives of patients, and the careers of those who do it.

Position Summary

Bristol Myers Squibb is seeking an enthusiastic, self-driven individual to join the Gene Delivery and Editing Process Development team within the Cell Therapy Development organization. The Gene Delivery and Editing Process Development team develops the processes and technologies underpinning critical raw materials used in the manufacturing of engineered T cells. The primary focus of this Associate Scientist will be to support process development, production, and characterization of early and late-stage viral vectors (lentiviral vectors and/or adeno-associated viruses). This position will be providing technical subject matter expertise with internal and/or external development and manufacturing collaborators for activities including tech transfer, process characterization, and pre-clinical or clinical process lifecycle management.

Key Responsibilities

• Perform hands-on experimental work in the early-phase development and optimization of primarily upstream (mammalian cell culture, stirred tank bioreactors, and transient transfection) unit operations for viral vector production. Experience in downstream (clarification, AEX chromatography, Tangential Flow Filtration) viral vector production is a bonus.
• Support process and technology development for viral vector manufacturing platforms
• Support late-phase development activities including process characterization
• Design, plan, execute, and analyze lab experiments using statistical design of experiment (DOE) principles
• Maintain proper documentation of experimental results using an electronic lab notebook
• Summarize and present scientific data; communicate progress to project teams
• Author technical documents including protocols and internal development reports
• Follow lab safety rules and practices

Qualifications & Experience

• B.S. with 5+ years or M.S. with 2+ years of hands-on upstream experience (downstream is a plus)
• Ability to design experiments with design of experiment (DOE) approaches, perform experiments, and interpret the results using statistical software (ex. JMP)
• Independently motivated with ability to multi-task, problem-solve, train team members on lab operations, and coordinate activities within a team
• Desire and drive to learn the biological mechanism of cell and gene therapy products and passion for their impact on the lives of patients with serious diseases
• Ability to communicate clearly and concisely through oral presentation and technical writing
• Embrace BMS shared values of passion, innovation, urgency, accountability, inclusion and integrity.

We hire for skills and capabilities, not just credentials - if this role excites you, but doesn’t perfectly match your resume, we encourage you to apply anyway.

Compensation Overview:

The starting pay range(s) listed above is for full-time employees (FTE). You may also be eligible for additional discretionary incentive cash and stock opportunities. We determine starting pay thoughtfully - carefully considering the nature of the role, required skills, work location, schedule and the knowledge and experience you bring. Final compensation is guided by pay equity principles and applicable employment laws. Compensation programs are reviewed on an ongoing basis and may be adjusted over time to reflect evolving market factors, and individual, team or Company performance.

Benefits:

Subject to the terms and conditions of the applicable plans then in effect, you may be eligible to participate in our comprehensive benefit plans - including wellbeing support, retirement and financial protection benefits, and insurance offerings (medical, dental, vision, life and disability).

U.S.-based exempt employees are eligible for Flexible Time Off (FTO), which provides paid time off without a set accrual limit, subject to manager approval, along with 11 paid company holidays each year.

Non-exempt employees, RayzeBio employees, and employees located in Puerto Rico receive 160 hours of paid vacation annually for new hires (subject to manager approval), 11 paid company holidays, and 3 optional holidays.

Depending on eligibility, employees may also have access to additional time-off benefits, including paid sick leave, up to two paid volunteer days per year, summer hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs. Eligible employees also enjoy an annual Global Shutdown between Christmas Day and New Year's Day.

U.S.-based job seekers can explore full benefit offerings athttps://careers.bms.com/benefits

How We Work

Where you work matters - because collaboration, innovation and patient impact happen in many settings. Our roles are structured across four work models: site-essential, site-by-design, field-based and remote-by-design. The model assigned to this role is based on its core responsibilities. Learn more at https://careers.bms.com/ways-of-working.

Supporting People with Disabilities

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [email protected]. Visit careers.bms.com/eeo-accessibility to access our complete Equal Employment Opportunity statement.

Candidate Rights

BMS will consider qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

For roles based in Los Angeles County only: If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information: https://careers.bms.com/california-residents/

Data Protection

We will never request payments, financial information, or social security numbers during our application or recruitment process. Learn more about protecting yourself at https://careers.bms.com/fraud-protection.

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

If this posting is missing required information required by local law or incorrect, contact BMS at [email protected] with the Job Title and Requisition number. Do not send application-related inquiries to this email. To check your application status, please login to your Candidate Home Account.

R1605145 : Senior Associate Scientist, Gene Delivery and Editing Process Development