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Salary
≈ $55k – $115k per year (Estimated)
Location
In office (Irving)
Seniority
Middle · 3+ years exp
Employment
Full-Time

Confirmed on the employer's own hiring board on Oct 25, 2026. First seen by Alion on Oct 21, 2026. Caris Life Sciences scores A on the Alion truth index.

Overview
Company
Impact
Profile match
Caris Life Sciences is a precision medicine company headquartered in Irving, Texas, that provides molecular tumor profiling, blood-based cancer diagnostics and AI-driven data services to oncologists, researchers and pharmaceutical partners. Founded in 2008, it runs laboratories in Phoenix and Tempe, Arizona, sells through oncology account executives across the US and is listed on the Nasdaq exchange. It hires oncology account executives, specimen processing clerks, bioinformatics scientists, Salesforce architects, liquid biopsy product managers and corporate security and executive protection staff.
Backed by Coatue

At Caris, we understand that cancer is an ugly word-a word no one wants to hear, but one that connects us all. That’s why we’re not just transforming cancer care-we’re changing lives.

We introduced precision medicine to the world and built an industry around the idea that every patient deserves answers as unique as their DNA. Backed by cutting-edge molecular science and AI, we ask ourselves every day:“What would I do if this patient were my mom?”That question drives everything we do.

But our mission doesn’t stop with cancer. We're pushing the frontiers of medicine and leading a revolution in healthcare-driven by innovation, compassion, and purpose.

Join us in our mission to improve the human condition across multiple diseases. If you're passionate about meaningful work and want to be part of something bigger than yourself, Caris is where your impact begins.

Position Summary

The Payroll Administrator is responsible for overseeing the entire payroll process, ensuring accurate and timely payments for a multi-state and international workforce. Additionally, the Payroll Administrator plays a pivotal role in streamlining operations, implementing best practices, and driving continuous improvement.

Job Responsibilities

  • Manage the day-to-day payroll operations, including processing, and compliance

  • Process biweekly US payroll and monthly international payroll, then transfer that information to the general ledger while maintaining detailed records and reconciling payroll data to ensure accuracy.

  • Develop and implement long-term payroll strategies that align with the company's overall business objectives.

  • Stay up-to-date with federal, state, and local payroll regulations to ensure the organization remains compliant.

  • Identify opportunities to streamline processes, reduce costs, and enhance efficiency.

  • Audit timesheets, taxation, garnishment deductions, benefit, and 401k deductions to guarantee accuracy and compliance.

  • Process garnishment paperwork and maintain garnishment records in payroll system.

  • Address employee queries related to payroll promptly and professionally.

  • Research, analyze, and resolve all issues and discrepancies, reporting to management as needed.

  • Register with tax agencies as needed, ensuring compliance with regulatory requirements.

  • Assist with payroll and timekeeping training for new employees and managers.

  • Support HR Operations by answering employee queries, processing employment verifications, and maintaining accurate records.

  • Work with 3rd party tax service vendor to ensure timely and accurate tax processing.

  • Prepare and distribute biweekly and monthly payroll related reports.

Required Qualifications

  • 3-5 years of experience managing & processing payroll for a mid-sized organization or equivalent experience in accounting.

  • Strong understanding of payroll accounting principles, tax laws, and regulatory compliance.

  • A strategic mindset with the ability to think critically and solve complex problems.

  • Proficiency in payroll software and systems

  • Strong detail orientation.

  • Excellent verbal and written communication skills, including active listening skills.

  • Technically savvy and proficient in Microsoft Office programs.

Preferred Qualifications

  • Bachelor's degree in human resources, accounting, finance, or equivalent experience.

  • Experience in Workday Payroll strongly preferred.

  • Certified Payroll Professional

Physical Demands

  • Employee may be required to lift heavy supplies; may weigh up to 25 pounds (including office supplies).

  • Ability to sit for extended periods of time.

  • Ability to be in front of a computer screen the majority of the work day.

  • Must possess ability to perform repetitive motion.

  • Majority of work is performed in a desk/cubicle environment.

Training

  • Job-specific, safety, and compliance training

Other

  • Willingness to work overtime when needed.

  • Job may require after-hours response to emergency issues.

  • Weekends/Evenings/Holidays- rarely

Conditions of Employment: Individual must successfully complete pre-employment process, which includes criminal background check, drug screening, credit check( applicable for certain positions) and reference verification.

This job description reflects management’s assignment of essential functions. Nothing in this job description restricts management’s right to assign or reassign duties and responsibilities to this job at any time.

Caris Life Sciences is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, religion, color, national origin, gender, gender identity, sexual orientation, age, status as a protected veteran, among other things, or status as a qualified individual with disability.

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