{"id":4272952,"url":"https://alion.io/job/catalent-scientist-process-development-downstream","title":"Scientist – Process Development, Downstream","company":{"id":1785256,"name":"Catalent","domain":"catalent.com","url":"https://alion.io/company/catalent-com","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Madison, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":null,"experience_years_min":6,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Chromatography","optional":false},{"name":"GMP","optional":false},{"name":"Microsoft Office","optional":false}],"status":"live","first_seen_at":"2026-11-13T18:24:59Z","employer_posted_date":"2026-11-13","last_verified_at":"2026-11-13T18:24:59Z","board_verified":true,"closed_at":null,"days_open":0,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":0},"description":"Scientist - Process Development, Downstream\nCatalent is seeking Scientists, Process Development - Downstream to support the development, optimization, characterization, and transfer of purification processes for biologics manufacturing.\nScientists in this role combine strong laboratory expertise in protein purification with data analysis, technical problem-solving, technical writing, and cross-functional collaboration to deliver high-quality process solutions for internal and client programs.\nAbout Catalent Madison: Catalent's Madison, Wisconsin facility is a state-of-the-art biologics development and manufacturing site supporting customers from research through early- and mid-stage clinical production. Located at 726 Heartland Trail, the 102,700-square-foot GMP facility specializes in mammalian cell line engineering, drug substance manufacturing, and biopharmaceutical process development.\nThe site is home to Catalent's proprietary GPEx® and GPEx® Lightning technologies, enabling the generation of high-producing mammalian cell lines for biologic therapies. With production capabilities ranging from 50L to 4,000L and a recent $45 million expansion, the Madison campus continues to play a critical role in Catalent's global biologics network while supporting Wisconsin's growing life sciences industry.\nLocation: 100% Onsite at our facility in Madison, Wisconsin \nShift: Monday - Friday, First Shift\nKey Responsibilities:\n Laboratory Execution: Independently perform downstream purification experiments, including automated chromatography (ÄKTA platforms), filtration, clarification, column packing, and tangential flow filtration (TFF/UF/DF). \n Process Development & Optimization: Lead the design, optimization, and characterization of downstream purification operations (including chromatography, depth filtration, and UF/DF) for monoclonal antibodies (mAbs) and bispecific constructs across the full product lifecycle.\nTechnical Leadership & Client Interaction: Serve as technical lead for client development or transfer projects, effectively communicating project status, technical rationales, and experimental results internally and externally. \n Documentation & GMP Compliance: Author, review, and maintain GMP-compliant technical documents-including protocols, SOPs, test reports, and batch production records (BPRs)-in accordance with Good Documentation Practices (GDP). \nData Analysis & Mentorship: Critically analyze complex experimental data using sound scientific judgment, while helping train, coach, and mentor junior team members on laboratory procedures. \nOther responsibilities as needed. \nRequired Qualifications:\nBachelor's degree in a STEM discipline with a minimum of 6 years relevant experience, Master's degree with a minimum of 3 years relevant experience, or PhD with relevant academic experience. \nHands-on experience with process-scale chromatography and filtration (chromatography, tangential flow filtration, normal flow filtration). \nExperience operating, maintaining, and troubleshooting chromatography workstations and process skids (e.g., ÄKTA platforms). \nDemonstrated knowledge of protein purification principles, methods, scale-up concepts, and modes of chromatography. \nStrong working knowledge of Good Documentation Practices (GDP), aseptic techniques, and technical document authoring (protocols, SOPs, batch records, reports). \nAbility to independently design, execute, analyze, and troubleshoot complex laboratory experiments under accelerated timelines. \nProficiency with Microsoft Office applications (Excel, Word) and laboratory or manufacturing software systems. \nPreferred Qualifications:\nExperience in early-stage biologics process development, clone/candidate screening, method adaptation, or process optimization. \nDirect experience with technology transfer into cGMP manufacturing, scale-up parameters, viral clearance validation, or process characterization. \nExperience in a cGMP-regulated biopharmaceutical, biotechnology, or CDMO environment. \nExperience using quality systems for tracking deviations, investigations, and change controls. \nDemonstrated experience mentoring and training junior scientific staff. \nExcellent client-facing and communication skills, with experience leading technical project discussions and client updates. \nWhy you should join Catalent:\nOpportunity to play a key role in driving growth within a global CDMO leader. \nCompetitive compensation package, including incentive opportunity. \nDay-one medical, dental, and vision coverage. \n401(k) with company match. \nTuition reimbursement and professional development opportunities. \nGenerous paid time off and holiday schedule (152 hours + 8 holidays) \nCollaborative, mission-driven culture focused on improving patient outcomes worldwide\nCatalent offers rewarding opportunities to further your career! Join the global drug development and delivery leader and help us bring over 7,000 life-saving and life-enhancing products to patients around the world. Catalent is an exciting and growing international company where employees work directly with pharma, biopharma and consumer health companies of all sizes to advance new medicines from early development to clinical trials and to the market. Catalent produces more than 70 billion doses per year, and each one will be used by someone who is counting on us. Join us in making a difference.\npersonal initiative. dynamic pace. meaningful work.\nVisit Catalent Careers to explore career opportunities.\nCatalent is an Equal Opportunity Employer, including disability and veterans.\nIf you require reasonable accommodation for any part of the application or hiring process due to a disability, you may submit your request by sending an email, and confirming your request for an accommodation and include the job number, title and location to . This option is reserved for individuals who require accommodation due to a disability. Information received will be processed by a U.S. Catalent employee and then routed to a local recruiter who will provide assistance to ensure appropriate consideration in the application or hiring process.\nNotice to Agency and Search Firm Representatives: Catalent Pharma Solutions (Catalent) is not accepting unsolicited resumes from agencies and/or search firms for this job posting. Resumes submitted to any Catalent employee by a third party agency and/or search firm without a valid written & signed search agreement, will become the sole property of Catalent. No fee will be paid if a candidate is hired for this position as a result of an unsolicited agency or search firm referral. Thank you.\nImportant Security Notice to U.S. Job Seekers:\nCatalent NEVER asks candidates to provide any type of payment, bank details, photocopies of identification, social security number or other highly sensitive personal information during the offer process, and we NEVER do so via email or social media. If you receive any such request, DO NOT respond- it is a fraudulent request. Please forward such requests to  for us to investigate with local authorities.\nCalifornia Job Seekers can find our California Job Applicant Notice HERE.\nVolunteer Work Disclosure: Applicants for employment in Massachusetts may include in their employment history any verified work performed on a volunteer basis.\nMassachusetts Lie Detector Test Notice: It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law may be subject to criminal penalties and civil liability. Consistent with Massachusetts law, Catalent does not require or administer lie detector tests as a condition of employment or continued employment.","description_format":"text","description_chars":7771,"description_truncated":false,"requirements":{"experience_years_min":6,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Professional development"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Laboratory Equipment","Dietary Supplements","Contract Manufacturing","CRO & CDMO Services"],"lifecycle":[{"event":"open","at":"2026-11-13T18:24:59Z"}],"visa":[],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":0,"expected_fill_days":33,"reasons":["conf:2","win:early","comp:brand"],"computed_at":"2026-11-13T20:25:44Z"},"pay":null,"html_url":"https://alion.io/job/catalent-scientist-process-development-downstream","json_url":"https://alion.io/job/catalent-scientist-process-development-downstream.json","meta":{"generated_at":"2026-11-13T20:25:44Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":40738,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-14T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1785256},"rest":"https://alion.io/mcp/rest/get_company?id=1785256"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcatalent-scientist-process-development-downstream"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"free","price":{"credits":0,"usd":0},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcatalent-scientist-process-development-downstream"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcatalent-scientist-process-development-downstream"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/catalent-scientist-process-development-downstream\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcatalent-scientist-process-development-downstream"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":4272952}},{"tool":"search_jobs","arguments":{"company":"catalent.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":4272952},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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