{"id":2541929,"url":"https://alion.io/job/celcuity-senior-or-principal-scientist-formulation-and-process-development","title":"Senior or Principal Scientist, Formulation and Process Development","company":{"id":2178715,"name":"Celcuity","domain":"celcuity.com","url":"https://alion.io/company/celcuity","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"BambooHR","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"lead","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":150000,"max":175000,"currency":"USD","period":"year","gross":null,"usd_annual":175000},"salary_estimate":null,"experience_years_min":7,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Microsoft Office","optional":true}],"status":"live","first_seen_at":"2026-09-24T00:00:00Z","employer_posted_date":"2026-09-24","last_verified_at":"2026-10-29T02:35:37Z","board_verified":true,"closed_at":null,"days_open":35,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":35},"description":"We are seeking a Senior or Principal Scientist, Formulation and Process Development, who will report to the Director, Pharmaceutical Development. You will focus on leading formulation and process development work supporting Celcuity’s drug product development and product lifecycle management. The Sr./Principal Scientist role will join a collaborative Pharmaceutical Development group focused on advancing Celcuity’s lead drug candidates. The Sr./Principal Scientist will lead formulation and process development projects for novel formulations targeted toward existing and new indications, as well as projects supporting Celcuity’s existing oncology drug product. This position will be remote.\nResponsibilities:\nLead projects to support development of novel and existing formulations, spanning the product lifecycle including pre-formulation, dosage form selection, formulation development, process development, and manufacturing scale-up.\nDesign, execute, and interpret formulation and process development experiments in an outsourced environment at contract laboratories and CDMOs.\nIdentify and vet new contract organizations to support formulation and process development.\nHelp define & execute the project plans for formulation lifecycle management.\nSupport writing technical sections for intellectual property and regulatory filings.\nDevelop and maintain an in-depth knowledge of formulation development trends, techniques, and technologies.\nServe as a subject matter expert for formulation development within the Pharmaceutical Development group and the broader Celcuity team.\nSummarize, document, and present information to subgroup, group, and cross-functional audiences.\nOther duties as assigned.\nQualifications:\nPh.D/M.S./B.S. in Pharmaceutical Science, Chemical Engineering, Chemistry, Biochemistry, Biochemical Engineering, or related fields.\n7+ years of experience in pharmaceutical development (preferred 4+ years industry experience for Ph.D; 5+ years for M.S.; 7+ years for B.S.).\nDemonstrated experience with formulation development and drug product development, preferably for small molecule drugs.\nDeep understanding of formulation techniques & considerations for sterile, parenteral dosage forms. Knowledge of other dosage forms (e.g., for ophthalmic or oral) is beneficial.\nExperience with drug device combination products for injectable drug products (e.g., prefilled syringes, autoinjectors) is preferred. Knowledge of other dosage form delivery techniques (e.g., for ophthalmic) is beneficial.\nTechnical expertise in formulation strategies and processes specifically tailored to poorly water-soluble APIs is preferred. Subject matter expertise in one or more of these areas is highly desirable:Nano-milling and nanosuspension formulation.\nMicro/nano-emulsions.\nSalt formation and salt screening/selection.\nComplexation and co-solvency using cyclodextrins or co-solvents.\nLyophilization\n\nExperience with physicochemical characterization methods for drug substances and drug products.\nExperience with preclinical study support and early-stage formulation development.\nExcellent written and verbal communication skills, with ability to influence and build credibility at all levels.\nStrong interpersonal skills for interacting with colleagues across various levels and functions.\nAttention to detail and ability to manage multiple processes and documentation requirements.\nStrong technical and analytical skills with advanced knowledge in MS Office products.\nAbility to work in a team or independently as required.\nOutstanding organizational skills with the ability to prioritize.\nDemonstrated independent and sound decision-making skills; ability to think critically and make decisions in a fast-paced environment.\nFlexible and willing to learn; able to adapt to business and site needs in a dynamic environment.\nMaintain a positive, approachable and professional attitude.\nAbout Us:\nCelcuity is a commercial biotechnology company pursuing development of targeted therapies for treatment of multiple solid tumor indications. The company's first FDA-approved product is REVTORPYK (gedatolisib), a potent, pan-PI3K and mTORC1/2 inhibitor that comprehensively blockades the PAM pathway. REVTORPYK is approved to treat adults with HR+/HER2- advanced breast cancer that progressed on prior endocrine therapy in the metastatic setting.\nThe Phase 3 VIKTORIA-2 trial is evaluating gedatolisib in combination with palbociclib and either fulvestrant or letrozole for the first-line treatment of HR+/HER2- locally advanced or metastatic breast cancer. A Phase 1/2 clinical trial evaluating gedatolisib in combination with darolutamide in patients with metastatic castration resistant prostate cancer, is ongoing.\nCelcuity is an Equal-Opportunity Employer.\nCelcuity is committed to fair and equitable compensation practices, and we strive to provide employees with total compensation packages that are competitive. For this role, the anticipated base pay range is $150,000 - $175,000 DOE. The exact base pay offered for this role will depend on various factors, including but not limited to the candidate’s geography, qualifications, skills, and experience.\nThe successful candidate will be eligible for an annual performance incentive bonus and a new hire equity package. Celcuity also offers various benefits offerings, including, but not limited to, medical, dental, vision insurance, 401(k) match, PTO, and paid holidays.\nNotice to Recruiters/Staffing Agencies\nRecruiters and staffing agencies should not contact Celcuity through this page. All recruitment vendors (search firms, recruitment agencies, and staffing companies) are prohibited from contacting our hiring manager(s), executive team members, or employees directly.\nWe require that all recruiters and staffing agencies have a fully executed, formal written agreement on file. Celcuity’s receipt or acceptance of an unsolicited resume submitted by a vendor organization to this website or employee does not constitute an actual or implied contract between Celcuity and such organization and will be considered unsolicited. Celcuity will not be responsible for related fees.","description_format":"text","description_chars":6149,"description_truncated":false,"requirements":{"experience_years_min":7,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity","Vision insurance"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Health Care","Oncology Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-14T15:50:13Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 1","filings_12m":1,"filings_prev_12m":0,"green_card_filings_12m":0,"median_offered_wage_usd":127500,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)"],"filings_for_role_12m":0}],"liveness":{"score":36,"band":"fade","label":"Fading","p_open":1,"p_active":0.662,"p_room":0.55,"age_days":35,"expected_fill_days":27,"reasons":["conf:3","win:tail"],"computed_at":"2026-10-29T05:49:05Z"},"pay":{"stated_usd_annual":175000,"is_top_pay":true},"html_url":"https://alion.io/job/celcuity-senior-or-principal-scientist-formulation-and-process-development","json_url":"https://alion.io/job/celcuity-senior-or-principal-scientist-formulation-and-process-development.json","meta":{"generated_at":"2026-10-29T06:19:22Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":9598,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-30T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":2178715},"rest":"https://alion.io/mcp/rest/get_company?id=2178715"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcelcuity-senior-or-principal-scientist-formulation-and-process-development"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcelcuity-senior-or-principal-scientist-formulation-and-process-development"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcelcuity-senior-or-principal-scientist-formulation-and-process-development"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/celcuity-senior-or-principal-scientist-formulation-and-process-development\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcelcuity-senior-or-principal-scientist-formulation-and-process-development"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":2541929}},{"tool":"search_jobs","arguments":{"company":"celcuity.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":2541929},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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