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Location
In office (San Francisco)
Employment
Full-Time

Confirmed on the employer's own hiring board on Sep 30, 2026. First seen by Alion on Jan 15, 2026. Chai Discovery scores C on the Alion truth index.

Overview
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Impact
Profile match
Chai Discovery is a San Francisco research company founded in 2024 that builds foundation models for molecular structure and interaction prediction. Its Chai-1 model predicts complexes of proteins, small molecules, nucleic acids and antibodies, and was released for free non-commercial use alongside a commercial offering. The company is backed by OpenAI and Thrive Capital and targets the design of antibodies and other biologics.

About Chai Discovery

Chai builds the design suite for molecules. We train frontier models that learn the underlying foundations of biochemical structure and interaction, so scientists can move faster and pursue targets that other methods cannot reach.

AI is reinventing life sciences the same way it reinvented software engineering, and Chai is at the forefront of this shift. Leading pharmaceutical companies like Eli Lilly, Pfizer, and Novartis are adopting our platform to power their drug discovery programs.

We value diverse perspectives and are ready to find greatness in unexpected places.

Can you help us?

We are looking for a few exceptional individuals to anchor our founding talent team -- with an emphasis on research and engineering hiring in the near term. We index on curiosity, taste, resourcefulness, IQ and EQ in equal measure.

#1 Build an incredible company.

You will help design every detail of this org. You will refine your nose for outlier talent and exceptional genius, wherever it may be found. You will relentlessly tackle every aspect of every assignment you take on. You'll work with our founders and leaders day in and out.

#2 Learn everything, communicate expertly.

This job demands that you can hold an intelligent conversation with anyone at any level. You will ravenously learn everything about what we're doing, why we're doing it, and where we're headed -- so that you can tell our story with passion and authenticity. You care and build trust by keeping it real.

#3 Think + act different.

We don't think the status quo is good enough, and neither do you. You have consistently shown innate ability to think and act beyond what is expected in order to achieve out-of-distribution results. You turn insight into action, optimize for iteration over perfection, and operate with urgency & creativity in equal measure.

Where could this lead?

You will walk away from this position knowing that you were a force multiplier in accelerating humanity's progress towards better medicines and better understanding of biology. You will gain the know-how and the network to establish yourself as an industry operator, bolstering any plans you might have to found your own company one day.

It will be a lot of fun, a lot of work, and extraordinarily rewarding.

We offer

The opportunity to work at the vanguard of AI research and frontier biology, with world-class people, on a mission that matters. We protect & promote a culture of high velocity and ownership. We compensate our team accordingly.

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