{"id":1092045,"url":"https://alion.io/job/colossal-senior-research-associate-computational-biology","title":"Senior Research Associate, Computational Biology","company":{"id":673658,"name":"Colossal Biosciences","domain":"colossal.com","url":"https://alion.io/company/colossal-4","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Dallas, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":90000,"max_usd":173000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1104},"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AWS","optional":false},{"name":"Azure","optional":false},{"name":"GCP","optional":false},{"name":"HPC","optional":false},{"name":"Java","optional":false},{"name":"Linux","optional":false},{"name":"MySQL","optional":false},{"name":"Perl","optional":false},{"name":"PostgreSQL","optional":false},{"name":"Python","optional":false},{"name":"Ruby","optional":false},{"name":"SLURM","optional":false},{"name":"CRISPR","optional":true}],"status":"live","first_seen_at":"2026-09-21T13:30:07Z","employer_posted_date":"2026-09-21","last_verified_at":"2026-10-23T00:30:03Z","board_verified":true,"closed_at":null,"days_open":31,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":31},"description":"An affiliate of Colossal is seeking a talented Senior Research Associate in computational biology with strong analytical skills to tackle challenging genotype-to-phenotype questions. The successful candidate will collaborate with scientists and engineers to perform bioinformatics analyses and integrate genomic, epigenomic, transcriptomic, and proteomic datasets to support Colossal Bioscience’s de-extinction efforts. The candidate must have experience in bioinformatics or computational biology.\nPreference will be given to candidates with a Masters degree who have experience analyzing and integrating diverse omics modalities (e.g., genomics, epigenomics, transcriptomics, proteomics) using functional annotations and ontologies in the context of data-sparse or non-model organisms.\nThis position will be based on-site in Dallas, TX. Relocation assistance is available.\nDuties and Responsibilities:\nRun data analysis with biological data\nRun comparative, functional, and statistical genomics analysis\nDevelop new tools in R/Python for data analysis and visualization\nMaintain electronic laboratory records and prepare reports or presentations to communicate findings to wet-bench biologists and leadership\nRequired Skills and Abilities:\nTwo years of bioinformatics experience in the following areas: Functional Genomics / Multi-Omics, Comparative Genomics, Molecular Evolution, or Applied Statistics in Genomics.\nCapable of leveraging knowledge across multiple levels of biological organization to validate the outputs of complex, integrative analyses.\nDemonstrated 2 years of experience with scripting languages, including but not limited to: Python, R, Perl, Ruby, Java, and BASH.\nAbility to write and run custom bioinformatics scripts using existing published tools and occasionally tools developed to summarize the results in a digestible manner and deliver the information using established reporting procedures.\nProficiency with handling large-scale genomic data in an HPC (SGE, SLURM, PBS) Linux and/or cloud environment (e.g. AWS, Google Cloud, Azure).\nExperience in using GIT version control software and maintaining well-documented, reproducible notebooks and workflows.\nAbility to design and maintain databases (MySQL, PostgreSQL, MongoDB) and connect with visual platforms to curate and share data with non-bioinformatics team members.\nSelf-motivated, proactive, and detail oriented, along with the ability to perform well under pressure and deadlines\nEnthusiasm for learning new skills and taking on new responsibilities\nStrong written and oral communication skills, as well as creative problem-solving skills\nAble to excel in a fast-paced startup environment and participate in team-driven science\nPreferred Skills and Abilities:\nExecuting rigorous analyses of diverse functional epigenomics approaches (e.g., RNA-seq and ATAC-seq) and integrating multi-omics datasets to aid in understanding of gene expression regulation\nConstructing, interpreting, and utilizing pangenome graphs, whole genome alignments, and gene homology relationships\nFamiliarity in producing and curating genomic resources (e.g., reference genomes and gene annotations) for vertebrate organisms, especially in non-traditional model systems.\nExperience calling germline and somatic sequence variants from high-coverage WGS, low-coverage WGS with imputation, and sequencing libraries from degraded or ancient DNA\nUnderstanding of precision gene editing technologies like CRISPR/Cas9 systems\nEducation and Experience:\nBachelors with 2 years of experience or Masters in quantitative or basic science (computer science, computational biology, bioinformatics, chemistry, physics, or mathematics preferred) is required\nWhat Colossal Offers Full-Time Employees:\nMedical, dental, and vision coverage\nExcellent paid time off and company holidays so you can rest and recharge \nFlexible spending accounts (FSA)\nCompany matched 401k retirement plan\nPaid parental leave at 100% salary for up to 12 weeks\nEducation reimbursement \nAn opportunity to help us return the Earth to a healthier state\nThe team at Colossal is committed, colorful, passionate, intelligent, collaborative, creative, experienced, scientific and world-class. That sounds like a lot to fit into one building. That’s why we are spread out in several locations that include laboratories, test facilities, academic institutions, libraries and offices. \nThrough it all, however, we maintain a culture of positivity, hope, happiness and belief that we’re doing something big. Something Colossal.\nColossal is proud to be an equal employment opportunity workplace. We welcome people from all backgrounds as well as celebrate and support diversity. We are committed to providing an inclusive environment of mutual respect that is free from discrimination and harassment so everyone can thrive. \nEEO is the Law \nSearch Firm Representatives: Colossal does not accept unsolicited assistance from search firms. No fees will be paid for a hired candidate where no pre-existing agreement is in place. We handle most recruitment in-house. \nColossal is on LinkedIn's 2026 Top Startups in Dallas List! See the list here.\nColossal is on Fortune's 2026 List for Best Workplaces in BioPharma. See the list here. \nColossal is proud to be named a Best Place to Work by BuiltIn for 4 years in a row across multiple categories in 2023, 2024, 2025, and 2026:\n#1 on the 50 Best Startups to Work For in Dallas in 2023!\n100 Best Midsize Places to Work in Dallas in 2024 & 2025\n100 Best Places to Work in Dallas, TX (All Size Employers) in 2024, 2025, and 2026.\nBuilt In 2026 Award Lists\nGreat Place to Work Certification Page\nMost Loved Workplace Certification Page - Proud to be certified as a most loved workplace including: most loved CEO, most loved workplaces for LGBTQ+, most loved workplaces for women, and most loved workplaces for young professionals.\nNewsweek's Most Loved Workplaces 2024 Award List - Excited to be amongst the winners of Newsweek's 2024 Most Loved Workplaces!","description_format":"text","description_chars":6006,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["401k plan","Parental leave","Relocation assistance","Retirement plans"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":true,"industries":["Bioinformatics","Synthetic Biology","Environmental Biotechnology"],"lifecycle":[{"event":"open","at":"2026-09-21T14:54:15Z"}],"visa":[],"liveness":{"score":69,"band":"ok","label":"Likely open","p_open":1,"p_active":0.769,"p_room":0.9,"age_days":30,"expected_fill_days":48,"reasons":["conf:0","win:mid"],"computed_at":"2026-10-22T06:10:10Z"},"pay":null,"html_url":"https://alion.io/job/colossal-senior-research-associate-computational-biology","json_url":"https://alion.io/job/colossal-senior-research-associate-computational-biology.json","meta":{"generated_at":"2026-10-23T04:07:01Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":6720,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-24T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":673658},"rest":"https://alion.io/mcp/rest/get_company?id=673658"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcolossal-senior-research-associate-computational-biology"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcolossal-senior-research-associate-computational-biology"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcolossal-senior-research-associate-computational-biology"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/colossal-senior-research-associate-computational-biology\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcolossal-senior-research-associate-computational-biology"}]}