{"id":340266,"url":"https://alion.io/job/conception-senior-scientist-rna-delivery","title":"Senior Scientist, RNA Delivery","company":{"id":100012,"name":"Conception","domain":"conception.bio","url":"https://alion.io/company/conception","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Berkeley, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":100000,"max_usd":197000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":1015},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Flow Cytometry","optional":false},{"name":"qPCR","optional":false},{"name":"Single-Cell Sequencing","optional":false}],"status":"live","first_seen_at":"2026-06-29T18:22:04Z","employer_posted_date":"2026-06-29","last_verified_at":"2026-10-28T02:10:08Z","board_verified":true,"closed_at":null,"days_open":120,"trust":{"level":"stale","repost_count":0,"flags":["stale"],"days_open":119},"description":"Experience level: PhD or equivalent industry experience.\nAbout Conception\nConception is pioneering the future of reproductive biology by generating functional human eggs from induced pluripotent stem cells (iPSCs). Our mission is to unlock new possibilities for fertility, reproductive health, and genetic diversity. We are building a world-class team at the intersection of stem cell biology, developmental biology, RNA biology, and synthetic biology to make this vision a reality.\nThe position\nWe are seeking a highly creative, rigorous, and hands-on Scientist with deep expertise in RNA delivery to help optimize and enhance Conception’s differentiation platform.\nThis position sits at the intersection of RNA biology, delivery technology, stem cell differentiation, and platform development. You will be responsible for building robust, scalable, and biologically effective delivery workflows that enable us to test and deploy programs across multiple differentiation contexts.\nWhat you’ll do\nDevelop RNA delivery workflows for payload expression in different cell types and culture set ups. Apply RNA delivery strategies to improve and accelerate Conception’s differentiation platform.\n\nOptimize RNA format, delivery chemistry and formulation, dose, timing, repeat delivery, expression, viability, and biological activity.\n\nBuild assays to measure delivery efficiency, target expression, and differentiation outcomes. Support screening workflows for RNA constructs, genes of interest, delivery conditions, and combinatorial perturbations.\n\nCollaborate across differentiation, cell engineering, and computational teams.\n\nWhat we’re looking for\nRequired\nPhD or equivalent experience in RNA Biology, Cell Biology, Stem Cell Biology, Bioengineering, Synthetic Biology, Developmental Biology, or a related field.\n\nHands-on experience delivering RNA into mammalian cells in various formats.\n\nExperience with most up to date RNA delivery technologies (LNPs, ligand conjugates, exosomes, electroporation, etc.) and standard readouts such as flow cytometry, imaging, qPCR, reporter assays, or RNA-seq.\n\nExperience delivering RNA or nanoparticles into complex culture systems.\n\nExperience optimizing delivery parameters such as dose, formulation, timing, repeat dosing, expression duration, toxicity, and biological effect.\n\nStrong experimental design, troubleshooting, documentation, and data interpretation skills.\n\nPreferred\nExperience with iPSCs, ESCs, primary cells, differentiating cells, or other difficult-to-transfect cell types.\n\nExperience using RNA-based differentiation approaches.\n\nExperience with different RNA format design, production, purification, characterization, or delivery.\n\nExperience with medium- or high-throughput screens, ORF libraries, combinatorial perturbations, or barcoded workflows.\n\nFamiliarity with scRNA-seq or related single-cell approaches.\n\nFamiliarity with developmental biology, reproductive biology, germ cell development, ovarian biology, or organoid systems.\n\nCome and work with us\nWe are well funded and well connected in Silicon Valley. We offer competitive pay, company equity, and excellent healthcare benefits for these positions.\nTo learn more about the original mouse proof of concept to live birth that inspired us, see https://www.nature.com/articles/nature20104","description_format":"text","description_chars":3312,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Cell & Gene Therapy","Fertility & IVF"],"lifecycle":[{"event":"open","at":"2026-09-05T18:02:25Z"}],"visa":[],"liveness":{"score":8,"band":"cold","label":"Long shot","p_open":1,"p_active":0.283,"p_room":0.28,"age_days":119,"expected_fill_days":30,"reasons":["conf:1","win:tail","crowd:"],"computed_at":"2026-10-27T05:46:45Z"},"pay":null,"html_url":"https://alion.io/job/conception-senior-scientist-rna-delivery","json_url":"https://alion.io/job/conception-senior-scientist-rna-delivery.json","meta":{"generated_at":"2026-10-28T04:29:31Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":5915,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-29T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":100012},"rest":"https://alion.io/mcp/rest/get_company?id=100012"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fconception-senior-scientist-rna-delivery"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fconception-senior-scientist-rna-delivery"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fconception-senior-scientist-rna-delivery"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/conception-senior-scientist-rna-delivery\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fconception-senior-scientist-rna-delivery"}]}