{"id":3396785,"url":"https://alion.io/job/copartner-revision-ag-postdoctoral-researcher","title":"Postdoctoral Researcher","company":{"id":682860,"name":"Copartner Revision AG","domain":"immune.engineering","url":"https://alion.io/company/immune-2","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Join","truth_index":null},"role":"AI/ML","role_family":"AI/ML","seniority":null,"employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Basel, Switzerland"],"countries":["CH"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":87000,"max_usd":212000,"period":"year","method":"role_country_seniority_unknown","sample_n":21},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Flow Cytometry","optional":false},{"name":"Machine Learning","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"Python","optional":false}],"status":"live","first_seen_at":"2026-10-28T06:39:08Z","employer_posted_date":"2026-10-28","last_verified_at":"2026-10-31T05:02:35Z","board_verified":true,"closed_at":null,"days_open":3,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":3},"description":"The group of Prof. Georg Seelig is seeking a highly skilled and innovative researcher with experience in performing and analyzing massively parallel reporter assays (MPRAs) to join our dynamic team. The ideal candidate will have a proven track record in engineering human cells (e.g. through genome editing, CAR or similar transgene integration etc). The candidate will also have experience in machine learning-guided design of proteins or cis-regulatory elements and related methods. This role involves the design of novel mRNA, gene or cell therapies with increased specificity.\nPrincipal Responsibilities\nDesigning and testing of synthetic cis-regulatory elements and other modalities for targeting activity of an mRNA or gene-based expression system to specific cell types.\n\nGenome engineering of human immune cells.\n\nDesigning and performing massively parallel reporter assays (MPRAs) with sequencing readouts to identify cis-regulatory elements that result in high mRNA stability, cell type or state-specific expression or similar.\n\nDeveloping and applying approaches for performing MPRAs in primary immune cells.\n\nDeveloping and applying novel single-cell analysis techniques including readout of reporter assays.\n\nCollaborating with cross-functional teams to advance testing of nucleic acid therapeutics.\n\nAnalyzing data, preparing detailed reports, planning follow-on experiments, and presenting findings to internal teams and at scientific conferences.\n\nStaying abreast of latest developments in genomics, synthetic immunology and related topics to continuously improve methodologies and outcomes.\n\nPreparing technical reports, summaries, protocols, and quantitative analyses.\n\nComposing scientific manuscripts for publication in peer-reviewed journals and patent applications.\n\nHelping train and mentor junior scientists and technical staff.\n\nRequired Qualifications and Skills\nPh.D. in Biomedical Engineering, Bioengineering or a related field.\n\nProven track record in performing sequencing-based high throughput assays (MPRAs, Sort-seq, etc.) to identify functional protein variants, cis-regulatory elements or to characterize transcription factors.\n\nStrong background in molecular biology and mammalian cell work, ideally including work with primary human immune cells or induced pluripotent stem cells.\n\nExperience with next generation sequencing, flow cytometry and related high throughput techniques.\n\nStrong track record in applying bioinformatics workflows for analysis of sequencing data.\n\nProven experience with data science, python programming, machine learning and related techniques.\n\nStrong communication skills with the ability to present complex scientific data to diverse audiences.\n\nAbility to work independently and constructively as part of a team in a collaborative scientific environment.\n\nAttention to detail and problem-solving skills, with a proactive approach to overcoming research and project challenges.","description_format":"text","description_chars":2943,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Science & 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