{"id":3296150,"url":"https://alion.io/job/copyright-axle-informatics-biological-scientist","title":"Biological Scientist","company":{"id":4416199,"name":"Axle","domain":"axleinfo.com","url":"https://alion.io/company/axleinfo","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":80,"open_postings":9,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":10,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Biotech","role_family":"Biotech","seniority":null,"employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Rockville, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":80000,"max":85000,"currency":"USD","period":"year","gross":null,"usd_annual":85000},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Cell Culture","optional":false},{"name":"Confocal Microscopy","optional":false},{"name":"CRISPR","optional":false},{"name":"Molecular Cloning","optional":false},{"name":"Next-Generation Sequencing","optional":false},{"name":"PCR","optional":false},{"name":"qPCR","optional":false},{"name":"Single-Cell Sequencing","optional":false},{"name":"Western Blot","optional":false}],"status":"live","first_seen_at":"2026-10-26T17:55:31Z","employer_posted_date":"2026-10-26","last_verified_at":"2026-11-03T02:22:43Z","board_verified":true,"closed_at":null,"days_open":7,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":7},"description":"(ID: 2026-3851)\nAxle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).\nAxle is seeking a Biological Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the National Center for Advancing Translational Sciences (NCATS) located in Rockville, MD.\nBenefits We Offer:\n100% Medical, Dental & Vision Coverage for Employees\nPaid Time Off and Paid Holidays\n401K match up to 5%\nEducational Benefits for Career Growth\nEmployee Referral Bonus\nFlexible Spending Accounts:Healthcare (FSA)\nParking Reimbursement Account (PRK)\nDependent Care Assistant Program (DCAP)\nTransportation Reimbursement Account (TRN)\n\nPosition Information:\nThis position designs, executes, and optimizes advanced molecular, cellular, genomic, and functional studies using genome engineering, stem cell biology, high-throughput screening, imaging, sequencing, and specialized analytical platforms to support mechanistic and translational research. The role also provides scientific and technical leadership in laboratory operations, quality control, instrumentation, data analysis, documentation, and multidisciplinary collaboration, contributing to research programs, publications, presentations, and grant-related activities\nAdditional Qualifications:\nField of Study\nBiology\n\nMolecular Biology\n\nSkills\nCell culture\n\nMolecular biology\n\nMolecular Biology Genome Engineering\n\nCell Stem Cell Biology\n\nGenomics Sequencing\n\nProtein Cellular Assays\n\nHigh-Throughput Screening\n\nAdvanced Instrumentation\n\nMicroscopy\n\nCell Banking Quality Control\n\nLaboratory Operations\n\nScientific Analysis Communication\n\nDeliverables:\nRun Validation - Ad-Hoc\n\nInspect Equipment - Ad-Hoc\n\nMeet with lab members to present updates - Weekly\n\nMolecular biology, genome engineering, and functional genomics work products related to experimental reports, protocols, construct maps, plasmid inventories, and technical documentation related to the design, execution, and optimization of molecular biology and cell-based experiments, including CRISPR genome editing, cloning, construct design, gene expression analysis, and functional genomics studies - Ad-Hoc\n\nMammalian cell culture work products, laboratory reports, and technical documentation related to the maintenance, expansion, characterization, and experimental use of stem cell lines, and differentiated cell populations - Ad-Hoc\n\nStem cell differentiation work products, protocols, differentiation records, assay results, and technical reports related to stem cell differentiation, optimization of culture conditions, and implementation of automated and high-throughput cell culture platforms - Ad-Hoc\n\nGenetic construct design and generation work products, construct designs, plasmid maps, cloning records, genome-editing validation reports, and associated documentation related to molecular cloning, plasmid engineering, CRISPR/Cas-mediated genome editing, and viral vector development - Ad-Hoc\n\nDNA, RNA, and protein isolation work products, laboratory reports, quality control documentation, and technical records related to the isolation, quantification, characterization, and storage of DNA, RNA, and protein samples from cellular and tissue specimens - Ad-Hoc\n\nGenomic sample preparation and sequencing support work products, sequencing preparation records, library preparation documentation, quality control reports, and technical documentation related to PCR, qPCR, next-generation sequencing (NGS), transcriptomics, and single-cell sequencing workflows - Ad-Hoc\n\nmulti-omics work products, sequencing reports, sample tracking records, analytical summaries, and technical documentation related to transcriptomic and genomic data generation workflows and coordination of downstream bioinformatics analyses - Ad-Hoc\n\nCell characterization and functional analysis work products, assay reports, experimental data, and technical documentation related to Western blotting, immunocytochemistry, immunofluorescence staining, and related protein and cellular characterization studies - Ad-Hoc\n\nTissue processing and histological analysis work products, microscopy datasets, tissue preparation records, cryostat sectioning documentation, image analysis reports, and technical documentation supporting cellular and molecular characterization studies - Ad-Hoc\n\nHigh-throughput assay development work products, assay development plans, validation reports, screening datasets, and technical documentation related to the development, optimization, validation, and implementation of high-throughput screening platforms, including bioluminescence-, fluorescence-, and reporter-based assays - Ad-Hoc\n\nLaboratory inventory management work products, inventory databases, reagent tracking systems, laboratory resource catalogs, and documentation related to establishing, maintaining, and updating inventories of reagents, antibodies, plasmids, cell lines, small molecules, consumables, and experimental protocols - Ad-Hoc\n\nStatement of Work Details:\nDesign, execute, and optimize molecular biology and cell-based experiments utilizing advanced techniques including CRISPR genome editing, cloning, construct design, gene expression analysis, and functional genomics approaches. - 1\n\nPrepare and process samples for next-generation sequencing (NGS), transcriptomic analyses, single-cell sequencing, PCR, qPCR, and other genomic applications, including library preparation and QC - 2\n\nConduct transcriptomic and genomic data generation workflows, including sample preparation, sequencing support, and coordination with bioinformatics teams for downstream analyses - 3\n\nCoordinate all aspects of cell banking and cell line stewardship, including cryopreservation, recovery, authentication, distribution, shipment and receipt of cell lines, and maintenance of associated records - 4\n\nCollaborate with multidisciplinary research teams, contributing scientific expertise in molecular biology, genome engineering, stem cell biology, assay development, and translational research to support program objectives and publications - 5\n\nProvides technical experience needed to assist in studying the basic principles of plant and animal life\n\nAssists with performing basic laboratory experiments and procedures\n\nCollect and analyze biological data about relationships among and between organisms and their environment\n\nMonitor and observe experiments, recording production and test data for evaluation by research personnel\n\nAnalyze experimental data and interpret results to write reports and summaries of findings\n\nCoordinate the work of biological technicians and technologists and other scientists\n\nPerform and optimize mammalian cell culture experiments, including maintenance of primary cells, stem cells, immortalized cell lines, and differentiated cell populations under sterile conditions\n\nDifferentiate stem cells into specialized cell types using established and novel protocols, automated culture systems, and high throughput platforms to support translational and mechanistic studies\n\nDesign and generate genetic constructs through molecular cloning, plasmid engineering, CRISPR/Cas-based genome editing, and viral vector preparation to support functional studies\n\nIsolate, quantify, and assess quality of DNA, RNA, and protein samples from cultured cells and tissue specimens using manual and automated workflows\n\nPerform protein characterization assays, including Western blotting, immunocytochemistry, immunofluorescence staining, and related molecular and cellular analyses\n\nPrepare and analyze tissue specimens using cryostat sectioning, microscopy, and histological techniques, supporting cellular and molecular characterization studies\n\nDevelop, validate, and implement high-throughput screening assays, including bioluminescence-, fluorescence-, and reporter-based assays for drug discovery and functional genomics applications\n\nPerform cellular functional assays using instrumentation such as Seahorse metabolic flux analyzers, multi-electrode arrays, flow cytometers, and other specialized research platforms\n\nCoordinate cell line QC programs, including mycoplasma testing, karyotyping, STR/DNA fingerprinting, contamination monitoring, and validation of genetically modified cell lines\n\nCollaborate with multidisciplinary research teams, contributing scientific expertise in molecular biology, genome engineering, stem cell biology, assay development, and translational research to support program objectives and publications\n\nPrepares, organizes and maintains various lab samples, supplies, and equipment\n\nOperate, calibrate, or maintain equipment used in quantitative or qualitative analysis, such as spectrophotometers, calorimeters, flame photometers, or computer-controlled analyzers\n\nMaintain laboratory equipment- Operate laboratory equipment to analyze samples\n\nAnalyze laboratory findings\n\nEstablish, maintain, and update laboratory inventories for reagents, antibodies, plasmids, cell lines, small molecules, consumables, and experimental protocols, ensuring accurate documentation and compliance with laboratory quality standards\n\nOperate and maintain advanced imaging systems, including fluorescence and confocal microscopy platforms, and perform quantitative image analysis to assess cellular phenotypes and molecular markers\n\nMaintain comprehensive laboratory records, including electronic laboratory notebooks, experimental protocols, standard operating procedures (SOPs), and regulatory documentation to ensure reproducibility and compliance\n\nMonitor laboratory instrumentation and infrastructure, including troubleshooting equipment, coordinating maintenance and service contracts, validating instrument performance, and training laboratory personnel on proper operation\n\nAnalyze, interpret, and present experimental data, prepare technical reports, manuscripts, protocols, and presentations, and contribute to grant applications, scientific publications, and collaborative research initiatives\n\nLearns new laboratory techniques and procedures\n\nProgram and use computers to store, process, and analyze data\n\nMonitor operational procedures in technical environments to ensure conformance to standards\n\nInterpret research or operational data\n\nRecord research or operational data\n\nDisclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.\nThe diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.\nAccessibility: If you need an accommodation as part of the employment process please contact: \nThis role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, quali...","description_format":"text","description_chars":12065,"description_truncated":true,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["401k plan"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Artificial Intelligence","Machine Learning"],"lifecycle":[{"event":"open","at":"2026-10-26T21:55:50Z"}],"visa":[],"liveness":{"score":76,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.803,"p_room":0.945,"age_days":6,"expected_fill_days":10,"reasons":["conf:2","velocity","win:mid"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":85000,"is_top_pay":false},"html_url":"https://alion.io/job/copyright-axle-informatics-biological-scientist","json_url":"https://alion.io/job/copyright-axle-informatics-biological-scientist.json","meta":{"generated_at":"2026-11-03T02:33:56Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":3365,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-04T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4416199},"rest":"https://alion.io/mcp/rest/get_company?id=4416199"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcopyright-axle-informatics-biological-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcopyright-axle-informatics-biological-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcopyright-axle-informatics-biological-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/copyright-axle-informatics-biological-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcopyright-axle-informatics-biological-scientist"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3296150}},{"tool":"search_jobs","arguments":{"company":"axleinfo.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3296150},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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