{"id":3428936,"url":"https://alion.io/job/copyright-axle-informatics-scientist-vpp","title":"Scientist","company":{"id":4416199,"name":"Copyright Axle Informatics","domain":"axleinfo.com","url":"https://alion.io/company/axleinfo","size_band":null,"is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":80,"open_postings":10,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":10,"computed_at":"2026-10-29T05:49:05Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Rockville, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":105000,"max":115000,"currency":"USD","period":"year","gross":null,"usd_annual":115000},"salary_estimate":null,"experience_years_min":6,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Chromatography","optional":false},{"name":"Design of Experiments","optional":false},{"name":"GMP","optional":false},{"name":"Outlook","optional":false},{"name":"Western Blot","optional":false}],"status":"live","first_seen_at":"2026-10-28T19:47:22Z","employer_posted_date":"2026-10-29","last_verified_at":"2026-10-29T21:15:12Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"(ID: 2026-3833)\nAxle is a bioscience and information technology company that offers advancements in translational research, biomedical informatics, and data science applications to research centers and healthcare organizations nationally and abroad. With experts in biomedical science, software engineering, and program management, we focus on developing and applying research tools and techniques to empower decision-making and accelerate research discoveries. We work with some of the top research organizations and facilities in the country including multiple institutes at the National Institutes of Health (NIH).\nAxle is seeking a Scientist to join our vibrant team at the National Institutes of Health (NIH) supporting the located in Gaithersburg, MD.\nBenefits We Offer:\n100% Medical, Dental & Vision Coverage for Employees\nPaid Time Off and Paid Holidays\n401K match up to 5%\nEducational Benefits for Career Growth\nEmployee Referral Bonus\nFlexible Spending Accounts:Healthcare (FSA)\nParking Reimbursement Account (PRK)\nDependent Care Assistant Program (DCAP)\nTransportation Reimbursement Account (TRN)\n\nAdditional Qualifications:\nCertifications & Licenses\nPh.D. in Chemical Engineering, Biology, Chemistry, or related Life Sciences field.\n\nM.S. degree with ≥6 years relevant experience will be considered.\n\nField of Study\nMiscellaneous Biology\n\nSoftware\nPowerpoint\n\nOutlook\n\nExcel\n\nWord\n\nSkills\n5-10 years of experience in industry-relevant recombinant protein process development for GMP clinical-phase products\n\nDemonstrated knowledge of maintaining accurate and detailed records\n\nExpertise in the following techniques or tools for protein and mRNA purification and characterization: Column chromatography for protein purification by means of AEX, CEX, affinity, SEC, HIC Column packing and testing AKTA chromatography system Lab scale TFF systems Lab scale nano-filtration systems Qualitative assays including SDS-PAGE and Western Blot UV/vis spectrophotometer\n\nMust be a team player who can effectively work with members from cross-functional departments\n\nStrong oral and written communication skills\n\nFamiliarity with computer software including word processing and data evaluation\n\nKnowledge and use of statistical design of experiments (DoE)\n\nDeliverables:\nClean Equipment - Ad-Hoc\n\nMeet with lab members to present updates - Ad-Hoc\n\nStatement of Work Details:\nDevelop downstream processes, with minimal oversight, for recombinant proteins such as monoclonal antibodies, subunit or nanoparticle vaccines, mRNA, mRNA-LNP, and virus-like particles (VLPs) that may be used as clinical therapeutic or vaccine candidates. - 1\n\nWork independently and collaboratively within the purification group to design, develop and optimize pDNA linearization, mRNA in vitro transcription (IVT), chromatography, Tangential Flow Filtration (TFF), and Normal Flow Filtration (NFF) processes for all clinical trial vaccine candidates. - 2\n\nApply process optimization methods, such as Design of Experiments (DoE) or other statistical design approaches. - 3\n\nSupports the planning and execution of research experiments in the context of the laboratory's overall research program.\n\nWrite and/or review appropriate CMC sections of IND filings (e.g. Process Description Summaries) to support VRC regulatory group.\n\nSupports laboratory staff on research projects and techniques.\n\nWork collaboratively with all VPP departments to coordinate schedules, material needs, and other deliverables to advance site-wide project goals.\n\nMaintains laboratory equipment and the training of others in their use.\n\nSupport Viral Clearance Validation studies.\n\nPurify research-phase recombinant proteins, virus vaccines, mRNA and/or virus-like particles in support of other groups at the VRC.\n\nAssists in maintaining adequate space and facilities for ongoing and projected research studies.\n\nDrive technology transfer of downstream processes to Lab’s Pilot Plant for manufacture of clinical product through document generation and on-site support.\n\nWrite and review technology transfer documents in support of GMP manufacturing.\n\nEvaluates, analyzes and interprets research data, communicates results and methods in reports, presentations, and manuscripts.\n\nPerform mRNA encapsulation to provide material generation for assay development and pre-clinical studies.\n\nAnalyze and compile data, present at various group/department meetings.\n\nWrite and review process batch records for toxicology batch productions.\n\nCoordinates with junior staff to modify research protocols.\n\nServe as a functional lead and/or Subject Matter Expert (SME) in an inter-department Chemistry, Manufacturing, and Control (CMC) team with responsibilities for the following processes: in vitro transcription (IVT), chromatography, depth filtration, nano-filtration, and tangential-flow filtration (TFF).\n\nTrain associate scientists in the execution of chromatography, filtration processes, and other newly developed and/or novel production processes.\n\nPresents research at national scientific meetings and symposia.\n\nPresent results of clinical and experimental research at recognized scientific meetings by lectures and exhibits (poster sessions).\n\nDisclaimer: The above description is meant to illustrate the general nature of work and level of effort being performed by individuals assigned to this position or job description. This is not restricted as a complete list of all skills, responsibilities, duties, and/or assignments required. Individuals may be required to perform duties outside of their position, job description or responsibilities as needed.\nThe diversity of Axle’s employees is a tremendous asset. We are firmly committed to providing equal opportunity in all aspects of employment and will not tolerate any illegal discrimination or harassment based on age, race, gender, religion, national origin, disability, marital status, covered veteran status, sexual orientation, status with respect to public assistance, and other characteristics protected under state, federal, or local law and to deter those who aid, abet, or induce discrimination or coerce others to discriminate.\nAccessibility: If you need an accommodation as part of the employment process please contact: \nThis role has a market-competitive salary with an anticipated base compensation range listed below. Actual salaries will vary depending on a candidate’s experience, qualifications, skills, and location.\nSalary Range\n$105,000—$115,000 USD","description_format":"text","description_chars":6495,"description_truncated":false,"requirements":{"experience_years_min":6,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["401k plan"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Artificial Intelligence","Machine Learning"],"lifecycle":[{"event":"open","at":"2026-10-28T23:31:52Z"}],"visa":[],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.632,"p_room":1,"age_days":0,"expected_fill_days":10,"reasons":["conf:2","stale_co","velocity","win:early"],"computed_at":"2026-10-29T05:49:05Z"},"pay":{"stated_usd_annual":115000,"is_top_pay":false},"html_url":"https://alion.io/job/copyright-axle-informatics-scientist-vpp","json_url":"https://alion.io/job/copyright-axle-informatics-scientist-vpp.json","meta":{"generated_at":"2026-10-29T23:41:23Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":34835,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-30T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4416199},"rest":"https://alion.io/mcp/rest/get_company?id=4416199"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcopyright-axle-informatics-scientist-vpp"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcopyright-axle-informatics-scientist-vpp"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcopyright-axle-informatics-scientist-vpp"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/copyright-axle-informatics-scientist-vpp\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcopyright-axle-informatics-scientist-vpp"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3428936}},{"tool":"search_jobs","arguments":{"company":"axleinfo.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3428936},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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