{"id":2896878,"url":"https://alion.io/job/cytokinetics-senior-scientist-ii-statistical-genetics","title":"Senior Scientist II, Statistical Genetics","company":{"id":1919595,"name":"Cytokinetics","domain":"cytokinetics.com","url":"https://alion.io/company/cytokinetics","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":100,"open_postings":10,"ghost_share":0,"stale_share":0,"repost_share":0,"time_to_fill_p50_days":51,"computed_at":"2026-10-26T05:57:25Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":184500,"max":215250,"currency":"USD","period":"year","gross":null,"usd_annual":215250},"salary_estimate":null,"experience_years_min":4,"visa_sponsorship":false,"relocation_package":false,"has_equity":true,"technologies":[{"name":"Python","optional":false},{"name":"AWS","optional":true},{"name":"GCP","optional":true},{"name":"GDPR","optional":true},{"name":"Machine Learning","optional":true}],"status":"live","first_seen_at":"2026-10-19T00:00:00Z","employer_posted_date":"2026-10-19","last_verified_at":"2026-10-25T06:58:16Z","board_verified":true,"closed_at":null,"days_open":7,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":7},"description":"Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction.\nWe are seeking a highly motivated and skilled statistical geneticist to join our growing team. You will play a critical role in discovering and evaluating therapeutic targets for diseases involving impaired cardiac and skeletal muscle function. You will lead hands-on research using large human cohorts, sequencing data and rich phenotypes to connect genetic variation with disease biology and therapeutic opportunities.\nThis role requires a strong foundation in statistical genetics, applied AI/ML experience, and a passion for translating genetic insights into clinical applications.\nResponsibilities:\nPerform common and rare variant association studies and meta-analyses across biobanks (e.g., UK Biobank, All of Us, FinnGen) to discover and replicate associations across diverse ancestries\nDevelop quantitative and longitudinal phenotypes from EHR and imaging (e.g., cardiac MRI, DEXA) using AI/ML methods to better capture disease biology\nApply fine-mapping, colocalization, Mendelian randomization and burden methods, including protein language model-based variant prioritization, to identify causal genes and direction of effect\nPrioritize targets using genetic evidence for efficacy and safety (e.g., PheWAS, allelic series, protective variants) and partner with experimental teams on validation\nBuild reproducible pipelines on research analysis platforms, and present findings internally, at conferences and in publications\nQualifications:\nPh.D. in Statistical Genetics, Human Genetics, Bioinformatics, Computational Biology or a related field with 4+ years of post-doctoral or industry experience\nStrong expertise in analyzing large-scale genomic datasets, including GWAS and sequencing data\nDemonstrated experience translating genetic associations into candidate therapeutic hypotheses or targets\nExperience with multidimensional and longitudinal data analysis in biology or medicine\nProficiency in R and/or Python, with experience applying and critically evaluating statistical and ML methods\nTrack record of independent research (e.g., first-author publications, methods, software) and strong communication skills\nPreferred Qualifications:\nExperience with cloud computing platforms (e.g., AWS, Google Cloud) and biobank research analysis platforms (e.g., UKB RAP, All of Us Workbench)\nExperience with machine learning and deep learning methods, and strong interest in applying these methods to biological problems\nPrevious therapeutic area experience in cardiovascular and neuromuscular disease is strongly desired\nExperience using AI-assisted coding tools in reproducible workflows\nYou don’t need every item on this list. We hire for judgment, rigor and curiosity.\nTo Apply:\nPlease submit your CV, a cover letter outlining your research experience and interests, and a list of publications.\nPay Range:\nThe expected salary range for this position based on the primary location of South San Francisco, CA is $184,500-$215,250. The base pay offered will take into account internal equity and may vary depending on the candidate's geographic region, job-related knowledge, skills, and experience among other factors. Base salary is just one component of our competitive total compensation package, which includes equity in the form of stock options and/or restricted stock units, comprehensive health, dental, vision, life and disability insurance coverage, 401k retirement benefits with employer match, learning and wellness stipends, and paid time off. Note that benefits are subject to change and may vary based on jurisdiction of employment.Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.\nPlease review our General Data Protection Regulation (GDPR) policy PRIOR to applying.\nOur passion is anchored in robust scientific thinking, grounded in integrity and critical thinking. We keep the patient front and center in all we do - all actions and decisions are in service of the patient and their caregivers. We champion integrity, ethics, doing the right thing, and being our best selves.\nFraud Warning: How to Identify Impersonated Cytokinetics Job Postings and Offers\nRecently, there have been fraudulent employment offers being sent to candidates on behalf of Cytokinetics. Please be advised that all legitimate offers from Cytokinetics will come directly from our official email domain (Cytokinetics.com) and will only be made after completing a formal interview process.\nHere are some ways to check for authenticity:\nWe do not conduct job interviews through non-standard text messaging applications\n\nWe will never request personal information such as banking details until after an official offer has been accepted and verified\n\nWe will never request that you purchase equipment or other items when interviewing or hiring\n\nIf you are unsure about the authenticity of an offer, or if you receive any suspicious communication, please contact us directly at \n\nPlease visit our website at: www.cytokinetics.com\nCytokinetics is an Equal Opportunity Employer","description_format":"text","description_chars":5598,"description_truncated":false,"requirements":{"experience_years_min":4,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["401k plan","Equity","Insurance coverage","Restricted stock units","Stock options"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Prescription Drugs","Cardiometabolic Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-20T05:11:28Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 6","filings_12m":6,"filings_prev_12m":10,"green_card_filings_12m":0,"median_offered_wage_usd":142500,"route":null,"cap_exempt":false,"checked_at":"2026-10-15T11:24:14+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":99,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.993,"p_room":1,"age_days":7,"expected_fill_days":51,"reasons":["conf:22","urgency","velocity","win:early"],"computed_at":"2026-10-26T05:57:25Z"},"pay":{"stated_usd_annual":215250,"is_top_pay":true},"html_url":"https://alion.io/job/cytokinetics-senior-scientist-ii-statistical-genetics","json_url":"https://alion.io/job/cytokinetics-senior-scientist-ii-statistical-genetics.json","meta":{"generated_at":"2026-10-26T11:00:18Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":14891,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-27T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1919595},"rest":"https://alion.io/mcp/rest/get_company?id=1919595"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fcytokinetics-senior-scientist-ii-statistical-genetics"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fcytokinetics-senior-scientist-ii-statistical-genetics"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fcytokinetics-senior-scientist-ii-statistical-genetics"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/cytokinetics-senior-scientist-ii-statistical-genetics\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fcytokinetics-senior-scientist-ii-statistical-genetics"}]}