Senior Director, FP&A

Deciphera, a member of Ono Pharmaceutical Co., Ltd., is a biopharmaceutical company focused on discovering, developing, and commercializing important new medicines and providing hope to people living with cancer, neurologic and autoimmune disease. Deciphera is leveraging its proprietary switch-control kinase inhibitor platform and deep expertise in kinase biology to develop a broad portfolio of innovative medicines. In addition to advancing multiple product candidates from Deciphera’s platform in clinical studies, QINLOCK® (ripretinib) is Deciphera’s switch-control kinase inhibitor approved in many countries including the European Union and the United States for the treatment of adult patients with advanced gastrointestinal stromal tumor (GIST) who have received prior treatment with 3 or more kinase inhibitors, including imatinib. ROMVIMZA® (vimseltinib) is a kinase inhibitor approved in the United States for adult patients with symptomatic tenosynovial giant cell tumor (TGCT) for which surgical resection will potentially cause worsening functional limitation or severe morbidity, and in the European Union for adult patients with TGCT associated with clinically relevant physical function deterioration and in whom surgical options have been exhausted or would induce unacceptable morbidity or disability.

The spirit of collaboration that has brought medications to life continues to guide how we operate, grow, and discover new breakthroughs. We cultivate an inclusive culture that values curiosity, creativity, and shared accountability-empowering individuals to challenge the unknown together.

Deciphera offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance and a flexible spending account for either health care and/or dependent care.

The Senior Director, Financial Planning & Analysis (FP&A) will lead Deciphera’s FP&A function and serve as a key strategic and financial partner to executive leadership, functional leaders, and Ono Pharmaceutical’s corporate headquarters in Japan. This highly visible role is responsible for leading company-wide budgeting, forecasting, and long-range financial planning while ensuring alignment between Deciphera’s business priorities and the broader Ono Pharma Group strategy.

The Senior Director will provide strategic financial leadership and analysis to support portfolio planning, investment decisions, and enterprise-wide resource allocation. Working closely with leaders across Deciphera and Ono Pharma headquarters, this individual will deliver financial insights, challenge key business assumptions, and help drive informed decision-making in support of both short- and long-term corporate objectives. In addition, the role will lead and develop a high-performing FP&A team while advancing the company’s financial planning, reporting, and decision-support capabilities to support continued growth and organizational success.

What You'll Do

Financial Planning & Analysis

• Lead the company's annual budget and quarterly forecasting processes, establishing financial targets, key assumptions, and planning timelines.
• Drive analysis of financial and operational performance against budget and forecast, identifying key drivers, risks, opportunities, and recommendations.
• Partner with functional leaders throughout the organization to provide financial guidance, challenge assumptions, and support informed decision-making.
• Lead financial reporting and forecasting activities in collaboration with Ono Pharmaceutical corporate headquarters.
• Develop impactful financial analyses, business cases, and executive-level presentations for senior leadership and global stakeholders.
• Ensure alignment between financial plans, strategic priorities, and operational objectives.
• Enhance and streamline FP&A processes, tools, reporting capabilities, and planning methodologies.

Strategic Finance

• Lead Deciphera's Strategic Finance function, providing direction and oversight on high-priority financial initiatives.
• Partner cross-functionally to support portfolio strategy, investment decisions, resource allocation, and business planning.
• Oversee financial modeling, scenario planning, and evaluation of strategic alternatives across development and commercial programs.
• Translate complex financial analyses into clear, actionable insights for executive leadership and corporate stakeholders.

Team Leadership

• Lead, coach, and develop a high-performing finance team.
• Establish clear goals, performance expectations, and career development plans.
• Foster a culture of accountability, operational excellence, continuous improvement, and collaboration.
• Build organizational capabilities that support Deciphera's growth and evolving business needs.

Other duties and responsibilities as assigned

• Bachelor's degree in Finance, Accounting, Economics, Business Administration, or a related discipline.
• 10+ years of relevant finance experience with significant FP&A and/or strategic finance leadership experience within the pharmaceutical or biopharmaceutical industry.
• Proven experience leading enterprise-wide budgeting, forecasting, and long-range planning processes.
• Strong financial and business acumen with demonstrated ability to influence strategic decisions through data-driven analysis.
• Experience developing and presenting financial insights to executive leadership teams.
• Demonstrated success leading, mentoring, and developing finance professionals.
• Exceptional communication, presentation, collaboration, and stakeholder-management skills.
• Ability to effectively partner with senior executives, cross-functional leaders, and global corporate stakeholders.

Preferred Qualifications

• Experience supporting portfolio planning, business development initiatives, and strategic investment decisions within the life sciences industry.
• Experience operating within a global organization and collaborating with international stakeholders and corporate headquarters.
• Advanced financial modeling, forecasting, and scenario-planning expertise.
• Proven ability to build scalable FP&A processes and reporting capabilities in a growing organization.
• Ability to thrive in a fast-paced, evolving environment while balancing strategic leadership with hands-on execution.
• Experience with enterprise planning and ERP systems; familiarity with Adaptive Insights and Oracle Fusion preferred.

Deciphera is committed to fair and equitable compensation practices. The base salary pay range for this role is $224,900- $309,200. Actual compensation packages will depend on various factors, including, but not limited to depth of experience, education, skillset, overall performance and/or location.

Deciphera believes in providing a competitive compensation and benefits package to all employees. Our base salary is just one component of Deciphera’s competitive total rewards strategy that also includes annual performance bonus, a long-term incentive plan, full range of benefits and other incentive compensation plans (if applicable)

Benefits:

• Competitive salary and annual bonus.
• Comprehensive benefits package including medical, dental, vision insurance, 401(k) retirement plan with company match, and more.
• Generous parental leave and family planning benefits.
• Outstanding culture and opportunities for personal and professional growth.

EQUAL EMPLOYMENT OPPORTUNITY INFORMATION

Deciphera is committed to equal employment opportunity and values diversity. To ensure that we comply with reporting requirements, we invite you complete the confidential survey at the end of this application. Providing this information is optional. It will not be accessible or used in the hiring process, and has no effect on your opportunity for employment. This information will also be treated confidentially. We are committed to make all hiring decisions and other employment decisions on a non-discriminatory basis.