{"id":3717263,"url":"https://alion.io/job/ecm-selection-senior-principal-systems-engineer","title":"Senior / Principal Systems Engineer","company":{"id":53991,"name":"ECM Selection","domain":"ecmselection.co.uk","url":"https://alion.io/company/ecm-selection","size_band":null,"is_staffing_agency":true,"employer_type":"agency","is_intermediary":false,"listed_via":null,"ats_vendor":"Schema","truth_index":{"grade":"B","score":75,"open_postings":13,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-11-04T06:34:25Z"}},"role":"Industrial Engineering","role_family":"Industrial Engineering","seniority":"lead","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Cambridge, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":90000,"max":90000,"currency":"GBP","period":"year","gross":null,"usd_annual":120747},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"ISO 13485","optional":false},{"name":"ISO 14971","optional":false},{"name":"PCR","optional":false}],"status":"live","first_seen_at":"2026-11-03T00:00:00Z","employer_posted_date":"2026-11-03","last_verified_at":"2026-11-04T20:29:35Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"Looking for a life science systems engineering and instrumentation expert. A serial deliverer of next-generation point-of-care and diagnostics device builds that incorporate sophisticated engineering with applied science capabilities.\nYou’ll be comfortable with PCR applications, microfluidics, optics and lasers as well as cartridge-based diagnostics. You can demonstrate concepts and innovative prototypes as well as take to manufacture low volume products. You are as comfortable working on your own in a lab / workshop as being part of a small senior team or leading a multidisciplinary group of engineers. You will understand the major global markets including the UK, EU, and USA. Moreover, you will also be capable of mentoring junior team members and be confident as a company representative at conferences and exhibitions.\nRequirements:\nExpert knowledge in systems engineering used for in vitro diagnostic devices / instruments in the life science and clinical markets. Must have demonstrable specialist understanding within this commercial business sector.\nUnderstanding of how to design systems that incorporate complex biochemical assays and how to deliver products to manufacture.\nStrong communications skills for stakeholder collaboration, technical leadership and mentorship.\nFamiliarity with relevant industry standards including ISO 13485, ISO 14971, 21CFR part 820 and MDR.\nThis is a senior, technical lead role with expectations of hands-on experience. Projects can be fast-paced with evolving requirements.\nInterested candidates are expected to have a strong academic background (degree in electronics, mechatronics or physics), but moreover have built a strong career in systems engineering for life sciences.\nOn offer is an excellent compensation package with a wide range of benefits. The role is expected to be onsite with hybrid work options possible (when projects allow). Some international travel would be required for client visits.\nKeywords: Applied Life Sciences, Systems Engineering, PoC, In Vitro Diagnostics, Instrumentation Development, ISO 13485, ISO 14971, Technical Leadership, Mentoring, Commercial Aptitude, Consultancy, Cambridge / Hybrid\nPlease note: even if you don't have exactly the background indicated, do contact us now if this type of job is of interest - we may well have similar opportunities that you would be suited to. And of course, we always get your permission before submitting your CV to a company.\nRecommend for £250 - see www.ecmselection.co.uk/tell-a-friend for details.","description_format":"text","description_chars":2532,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":null,"security_clearance":false,"languages":[]},"benefits":["Hybrid work"],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology"],"lifecycle":[{"event":"open","at":"2026-11-04T01:10:38Z"}],"visa":[],"liveness":{"score":38,"band":"fade","label":"Fading","p_open":1,"p_active":0.379,"p_room":1,"age_days":1,"expected_fill_days":28,"reasons":["conf:5","agency","stale_co","velocity","win:early"],"computed_at":"2026-11-04T06:34:25Z"},"pay":{"stated_usd_annual":120747,"is_top_pay":false},"html_url":"https://alion.io/job/ecm-selection-senior-principal-systems-engineer","json_url":"https://alion.io/job/ecm-selection-senior-principal-systems-engineer.json","meta":{"generated_at":"2026-11-04T22:52:46Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":1053,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-05T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":53991},"rest":"https://alion.io/mcp/rest/get_company?id=53991"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fecm-selection-senior-principal-systems-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fecm-selection-senior-principal-systems-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fecm-selection-senior-principal-systems-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/ecm-selection-senior-principal-systems-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fecm-selection-senior-principal-systems-engineer"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3717263}},{"tool":"search_jobs","arguments":{"company":"ecmselection.co.uk","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3717263},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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