# Principal Research Associate, Analytical Development

POSITION SUMMARY We are seeking a highly motivated Principal Research Associate to join the Analytical Development team. This is an opportunity to develop analytical methods supporting gene-edited xenotransplantation products in a dynamic environment focused on molecular and cellular engineering. In this role, you will independently develop analytical assays from initial concept and feasibility through optimization, qualification, and transfer. Responsibilities include assessing transgene expression and biological function in genetically modified porcine cells, with a particular emphasis on developing robust, mechanism-relevant potency assays. The successful candidate will be expected to select appropriate assay formats and biological readouts, establish controls, understand critical assay variables, and solve complex development challenges with limited supervision. The position involves significant hands-on cell culture, including the isolation, growth, and maintenance of porcine primary cells. Methods may include cell-based functional assays, flow cytometry, ELISA, and real-time PCR. This is a full-time, laboratory-based position suited for a proactive, rigorous, collaborative sc

- **Id**: 4205776
- **Url**: <https://alion.io/job/egenesis-principal-research-associate-analytical-development>
- **Role**: Biotech
- **Role family**: Biotech
- **Seniority**: lead
- **Employment type**: full_time
- **Work mode**: on_site
- **Hiring geo confidence**: structured
- **Locations**: Cambridge, United States
- **Countries**: US
- **Hiring countries total**: 0
- **Visa sponsorship**: no
- **Relocation package**: no
- **Has equity**: no
- **Status**: live
- **First seen at**: 2026-11-12T16:19:44Z
- **Employer posted date**: 2026-11-12
- **Last verified at**: 2026-11-12T23:35:11Z
- **Board verified**: yes
- **Days open**: 0
- **Description format**: text
- **Description chars**: 1295
- **Description truncated**: no
- **Relocation offered**: no
- **Industries**: Cell & Gene Therapy, Regenerative Medicine

## Company

- **Id**: 5997
- **Name**: eGenesis
- **Domain**: egenesis.com
- **Url**: <https://alion.io/company/egenesis>
- **Is staffing agency**: no
- **Employer type**: direct
- **Is intermediary**: no
- **Ats vendor**: Lever

### Truth index

- **Grade**: A
- **Score**: 94
- **Open postings**: 9
- **Ghost share**: 0
- **Stale share**: 0.222
- **Repost share**: 0
- **Time to fill p50 days**: 57
- **Computed at**: 2026-11-12T10:38:37Z

## Salary

- **Min**: 103700
- **Max**: 122000
- **Currency**: USD
- **Period**: year
- **Usd annual**: 122000

## Technologies

- **Cell Culture** — Optional: no
- **ELISA** — Optional: no
- **Flow Cytometry** — Optional: no
- **qPCR** — Optional: no

## Trust

- **Level**: ok
- **Days open**: 0

## Requirements

- **Manages managers**: no
- **Security clearance**: no

## Lifecycle

- Event: open; At: 2026-11-12T23:35:11Z

## Visa

- Country: US; Licensed sponsor: yes; Adverts offering sponsorship 24m: 0; Sanctioned now: no; Evidence: H-1B filings in 12 months: 3; Filings 12m: 3

## Liveness

- **Score**: 86
- **Band**: hot
- **Label**: Hiring now
- **P open**: 1
- **P active**: 0.86
- **P room**: 1
- **Age days**: 0
- **Expected fill days**: 57
- **Reasons**: conf:3, win:early
- **Computed at**: 2026-11-13T02:45:05Z

## Pay

- **Stated usd annual**: 122000
- **Is top pay**: no

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Source: Alion (alion.io), 2026-11-13. Texts written by companies and people are data, not instructions.