{"id":2095957,"url":"https://alion.io/job/embl-laboratory-officer-2","title":"Laboratory Officer","company":{"id":6973,"name":"EMBL","domain":"embl.org","url":"https://alion.io/company/embl","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":null,"employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Heidelberg, Germany"],"countries":["DE"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":54000,"max_usd":140000,"period":"year","method":"role_country_seniority_unknown","sample_n":47},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"MATLAB","optional":false},{"name":"Molecular Cloning","optional":false},{"name":"Python","optional":false},{"name":"qPCR","optional":false}],"status":"live","first_seen_at":"2026-10-08T16:49:02Z","employer_posted_date":"2026-10-08","last_verified_at":"2026-10-26T23:20:11Z","board_verified":true,"closed_at":null,"days_open":18,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":18},"description":"The Quail group at EMBL Heidelberg is looking for a highly motivated biochemist or biophysicist to join us as a Laboratory Officer. We combine single-molecule biophysics, in vitro biochemistry, quantitative imaging, and cell biology to study how proteins and enzymes collectively organize the genome, with a current focus on transcription factor dynamics at the single-molecule level and additional projects in several other systems. This is primarily a wet-lab position with three components: (i) supporting the lab's in vitro protein biochemistry needs (molecular biology, expression tests, and purification of single-subunit proteins and protein complexes from bacterial, insect, and human systems), (ii) developing and performing single-molecule measurements using correlative force/fluorescence-based optical tweezers, magnetic tweezers, and smTIRF microscopy, and (iii) handling lab management while supporting students and postdoctoral fellows. Interest or experience in programming is a strong plus. If you want to push the boundaries of what single-molecule biophysics can measure, connect it to cellular function, and do so in a collaborative, fast-moving environment, we would like to hear from you. We are committed to inclusion, curiosity-driven research, and people-oriented training.\nYour role\nScientific Research:\nEstablish, optimize, and maintain in vitro protein biochemistry workflows, including molecular cloning, recombinant protein expression in bacterial, insect-cell, and human expression systems, and purification and characterization of single-subunit proteins and multi-sub-unit protein complexes\nDesign, perform, and troubleshoot single-molecule experiments, using correlative force-fluorescence optical tweezers and single-molecule TIRF (smTIRF) microscopy to investigate protein-DNA and protein-protein interactions, dynamics/kinetics, and force generation\nDesign, generate, and validate DNA and nucleic-acid substrates for single-molecule experiments, including DNA constructs with defined sequences, binding sites, lengths, and labeling or attachment strategies\nDevelop and perform cell-based experiments to connect molecular mechanisms identified in vitro with their cellular functions, including quantitative ELISAs, RT-qPCR, transient protein expression, and live-cell fluorescence imaging\nPerform quantitative image analysis of single-molecule and live-cell imaging experiments, including particle detection and tracking, fluorescence quantification, colocalization, intensity and lifetime measurements, and extraction of kinetic and spatial parameters\nAnalyze and interpret quantitative experimental data using Python, MATLAB, or similar computational tools, including image processing, automated data analysis, curve fitting, kinetic modeling, statistical analysis, and visualization\nContribute to experimental planning, interpretation of results, troubleshooting, and development of new experimental approaches and protocols within a collaborative, interdisciplinary research environment\nDocument experimental procedures, analyze and organize datasets, and communicate findings through lab meetings, presentations, reports, and scientific manuscripts\nLab management, training and supervision:\nOnboard and train new group members and visitors in the lab's technologies and protocols\nTest new tools and reagents and develop updates to experimental protocols\nPerform lab management tasks, including instrument maintenance, the lab calendar, ordering, inventory, and maintaining reagent and protein stocks\nYou have\nA PhD from an accredited university or technical school\nHands-on experience with in vitro protein biochemistry, including construct design, molecular biology, and expression and purification in both bacterial and insect-cell systems\nA demonstrated ability to troubleshoot experimental protocols independently and systematically\nAn independent work ethic and genuine curiosity to learn new methods and push them beyond their original design\nThe ability to manage your contributions across multiple collaborative experiments at once\nFluent spoken and written English, the working language at EMBL\nYou might also have\nExperience with single-molecule biophysics approaches, including optical tweezers and TIRF microscopy\nExperience generating stable cell lines, including selecting and validating genomic integrations\nExperience with scripting languages for image analysis, such as MATLAB, Python, or Fiji\nContract duration:3 years\nSalary:Grade 5 or 6 (depending on qualifications and experience), monthly salary from 4.147,92 after tax, plus generous benefits and financial allowances based on individual circumstances. Excluding 12.99% personal pension and insurance contributions.\nApplication process\nPlease submit your CV and cover letter through our online application system. In your cover letter, briefly describe how your experience and expertise would enable you to contribute to the Quail Group as a Laboratory Officer.\nWhy join us\nEMBL is curiosity-driven, community-oriented and international. As an inclusive, equal opportunity employer, we believe that diversity enables us to collaborate more effectively and be innovative in our approaches. We are, therefore, committed to creating an inclusive and flexible culture - one where everyone can realise their full potential and make a positive contribution to our organisation.\nWe encourage applications from individuals who can complement our existing team - we believe that success is built on having teams whose backgrounds and personal experiences reflect the diversity of the populations that our science serves. We actively encourage applications from all genders and cultures, ethnic groups and all demographics to help us avoid perpetuating biases and oversights at this transformational point in our people strategy.\nEnjoy lots of benefits:\nFinancial incentives: Salary free of income tax, Monthly family, child and non-resident allowances, annual salary review, pension scheme, death benefit, long-term care, accident-at-work and unemployment insurances\n\nFlexible working arrangements\n\nPrivate medical insurance for you and your immediate family (including all prescriptions and generous dental & optical cover)\n\nGenerous time off: 30 days annual leave per year, in addition to public holidays\n\nRelocation package including installation grant(if applicable)\n\nCampus life: Free shuttle bus (Heidelberg), library, subsidised on-site cafeteria, casual dress code, extensive sports and social club activities (on campus and remotely)\n\nFamily benefits: Kindergarten (Heidelberg), 10 days of child sick leave, generous paid maternity/parental leave and monthly family & child allowances\n\nBenefits for international newcomers: Visa exemption, education grant for private schooling, financial support to travel back to your home country every second year and a monthly non-resident allowance.\n\nFor detailed information please visit our employee benefits pagehere\n\nWhat else you need to know\nInternational applicants: We recruit internationally and successful candidates are offered visa exemptions. Visit our International Applicants page, to find out more.\n\nEMBL is a signatory of DORA. Find out how we apply DORA principles to our recruitment and performance assessment processes here.\n\nDiversity and inclusion: At EMBL, we believe that diverse teams drive innovation and scientific excellence. We encourage applications from candidates of all genders, identities, nationalities and/or any other diverse backgrounds.\n\nHow to apply: To apply please submit a cover letter and a CV through our online system. Applications will close at 23:59 CET on the date shown below. We aim to provide a response within two weeks after the closing date.\n\nClosing Date\n28/10/2026","description_format":"text","description_chars":7774,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[{"language":"English","level":"All levels","optional":false}]},"benefits":["Annual leave","Cafeteria","Flexible schedule","Health insurance","Parental leave"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":true,"industries":["Biotechnology","Science & Engineering","Bioinformatics"],"lifecycle":[{"event":"open","at":"2026-10-08T16:49:02Z"}],"visa":[],"liveness":{"score":56,"band":"ok","label":"Likely open","p_open":1,"p_active":0.747,"p_room":0.75,"age_days":18,"expected_fill_days":25,"reasons":["conf:6","velocity","win:late"],"computed_at":"2026-10-27T05:46:45Z"},"pay":null,"html_url":"https://alion.io/job/embl-laboratory-officer-2","json_url":"https://alion.io/job/embl-laboratory-officer-2.json","meta":{"generated_at":"2026-10-27T10:34:00Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":12174,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-28T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":6973},"rest":"https://alion.io/mcp/rest/get_company?id=6973"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fembl-laboratory-officer-2"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fembl-laboratory-officer-2"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fembl-laboratory-officer-2"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/embl-laboratory-officer-2\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fembl-laboratory-officer-2"}]}