{"id":123034,"url":"https://alion.io/job/flagship-pioneering-principal-data-scientist","title":"Principal Data Scientist","company":{"id":8393,"name":"Flagship Pioneering","domain":"flagshippioneering.com","url":"https://alion.io/company/flagshippioneering","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":true,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":79,"open_postings":8,"ghost_share":0,"stale_share":0.75,"repost_share":0.125,"time_to_fill_p50_days":54,"computed_at":"2026-11-04T06:34:25Z"}},"role":"Data Science","role_family":"Data Science","seniority":"lead","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["Cambridge, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":179000,"max":236500,"currency":"USD","period":"year","gross":null,"usd_annual":236500},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Machine Learning","optional":false},{"name":"Python","optional":false},{"name":"SQL","optional":false},{"name":"Embeddings","optional":true},{"name":"Interpretability","optional":true},{"name":"Recommender Systems","optional":true}],"status":"closed","first_seen_at":"2026-08-25T15:21:19Z","employer_posted_date":"2026-10-05","last_verified_at":"2026-11-04T07:03:53Z","board_verified":false,"closed_at":"2026-11-04T07:03:53Z","days_open":70,"trust":{"level":"not_scored","repost_count":null,"flags":[],"days_open":70},"description":"COMPANY DESCRIPTION\nExtuitive is a Flagship Pioneering-backed startup reimagining product innovation for the AI era. Our mission is to revolutionize go to market for planning and execution for the agentic age. Based in Cambridge, MA, we operate like a special ops unit-fast-moving, data-driven, and relentlessly focused on impact.\nTHE ROLE\nAs a Principal Data Scientist, you’ll be a technical leader responsible for the full lifecycle of the models and data science systems that predict and optimize advertising performance across channels. You’ll define the learning problems, training data, targets, and business outcomes to influence; train and rigorously validate the right models offline; and take the technology to market through customer-facing validation. You’ll work across paid social, search, display, video, and emerging channels, translating complex, noisy advertising data into robust models, explainable decisions, and measurable customer value as our platform and data scale.\nKEY RESPONSIBILITIES\nDefine Learning Targets & Model Advertising Performance - Identify the customer decision and business intervention to influence; construct training labels and measurement windows; assess data quality, bias, and leakage; and develop predictive models that forecast campaign and creative performance across channels, audiences, placements, and objectives.\nBuild Cross-Channel Measurement & Optimization Systems - Develop methods to compare and optimize advertising performance across paid social, search, display, video, and other channels while accounting for differences in measurement, attribution, and data availability.\nDevelop Experimentation & Causal Measurement Approaches - Design and analyze experiments, incrementality tests, and causal inference approaches to verify that the targets we optimize change business outcomes, not just model metrics, and to distinguish correlation from true impact.\nTranslate Models into Marketable Decisions - Turn model outputs into clear, customer-facing recommendations for campaign strategy, budget allocation, targeting, creative selection, and optimization-decisions that can be explained, tested, and proven useful in market.\nAdvance Modeling & Validation Best Practices - Shape our approach to forecasting, experimentation, feature engineering, model selection, and production data science, including holdout and backtesting design, calibration, uncertainty, failure modes, data drift, and decision thresholds before production or customer exposure.\nOwn the Model Lifecycle Cross-Functionally - Partner across data, product, engineering, and customer discovery to move models from learning problem through deployment and customer validation, while supporting the quantitative work needed to make that lifecycle successful.\nPROFESSIONAL EXPERIENCE & QUALIFICATIONS \n8+ years of data science, machine learning, statistics, or related quantitative experience.\nAdvanced degree in Statistics, Mathematics, Economics, or another quantitative field, or equivalent practical experience.\nStrong expertise in Python, SQL, and modern data science and machine learning frameworks.\nStrong foundation in statistics, machine learning, experimental design, forecasting, and model evaluation.\nDemonstrated track record of taking models from research and experimentation through production deployment, customer validation, and measurable business impact.\nExperience modeling advertising, marketing, consumer, or marketplace performance, including metrics such as conversion, engagement, acquisition, ROAS, CAC, or lifetime value.\nExperience working with advertising data across multiple channels and platforms, including paid social, search, display, or video.\nExperience with causal inference, incrementality testing, attribution, media mix modeling, or related approaches to measuring marketing effectiveness.\nExceptional scientific communication skills, with the ability to earn trust across technical and non-technical stakeholders by clearly explaining assumptions, evidence, trade-offs, uncertainty, and validation results.\nComfortable working in a fast-paced, evolving environment with minimal oversight.\nNice to Have \nExperience building predictive advertising or marketing optimization products in an early-stage startup.\nDeep familiarity with advertising platform data and APIs, including Meta, Google, TikTok, LinkedIn, or similar platforms.\nExperience with budget optimization, bidding, recommendation systems, uplift modeling, or other decision-making systems.\nExperience applying LLMs, embeddings, or other foundation models to advertising, creative, or consumer data.\nExperience developing models in data-sparse or cold-start environments where historical performance data is limited.\nComfort with ambiguity and making trade-offs between modeling sophistication, speed, interpretability, and business impact.\nABOUT FLAGSHIP PIONEERING:\nFlagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. \nFlagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com.\nAt Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.\nWe are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.\nWe recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your backgroundand interest in Flagship.\nRecruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.\nPrivacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact . \nThe salary range for this role is $179,000 - $236,500. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Extuitive, Inc. currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Extuitive, Inc.'s good faith estimate as of the date of publication and may be modified in the future.\nPrivacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact .","description_format":"text","description_chars":9346,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":true},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Venture Capital"],"lifecycle":[{"event":"open","at":"2026-08-25T15:21:19Z"},{"event":"close","at":"2026-11-04T07:03:53Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 10 · green card filings: 2","filings_12m":10,"filings_prev_12m":3,"green_card_filings_12m":2,"median_offered_wage_usd":150833,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":null,"pay":{"stated_usd_annual":236500,"is_top_pay":true},"html_url":"https://alion.io/job/flagship-pioneering-principal-data-scientist","json_url":"https://alion.io/job/flagship-pioneering-principal-data-scientist.json","meta":{"generated_at":"2026-11-04T07:41:37Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":12013,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-05T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":8393},"rest":"https://alion.io/mcp/rest/get_company?id=8393"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fflagship-pioneering-principal-data-scientist"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fflagship-pioneering-principal-data-scientist"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fflagship-pioneering-principal-data-scientist"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/flagship-pioneering-principal-data-scientist\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fflagship-pioneering-principal-data-scientist"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":123034}},{"tool":"search_jobs","arguments":{"company":"flagshippioneering.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":123034},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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