{"id":2183272,"url":"https://alion.io/job/flagship-pioneering-scientific-manager-high-throughput-laboratory","title":"Scientific Manager – High Throughput Laboratory","company":{"id":8393,"name":"Flagship Pioneering","domain":"flagshippioneering.com","url":"https://alion.io/company/flagshippioneering","size_band":"1001-5000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":true,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":74,"open_postings":8,"ghost_share":0,"stale_share":0.75,"repost_share":0.125,"time_to_fill_p50_days":61,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":null,"work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"explicit","locations":["Cambridge, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":61000,"max_usd":108000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":19},"experience_years_min":6,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Flow Cytometry","optional":false},{"name":"Immunohistochemistry","optional":false},{"name":"LIMS","optional":false}],"status":"live","first_seen_at":"2026-10-09T14:07:37Z","employer_posted_date":"2026-10-09","last_verified_at":"2026-11-02T08:32:58Z","board_verified":true,"closed_at":null,"days_open":23,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":23},"description":"Position Summary:\nQuotient is seeking an experienced Scientific Manager to lead the day-to-day execution and delivery of our High Throughput Laboratory.\nReporting to the Head of High Throughput Laboratory, this role is responsible for coordinating laboratory activities across Histology, Flow Cytometry, Molecular Biology and Sample Management, ensuring samples move efficiently through laboratory workflows and disease programmes are delivered safely, on time and to the highest scientific standards.\nWorking closely with Research Project Management, Scientific Leadership, Genomic Scientists, the High Throughput Laboratory and Assay Development teams, you will translate project priorities into effective laboratory execution, balancing competing demands across multiple programmes while maintaining visibility of sample progression, laboratory capacity and resource utilisation.\nThis is a highly visible operational leadership role suited to someone who enjoys bringing structure to complex laboratory environments, developing high-performing teams and ensuring laboratory operations run efficiently. You will combine scientific credibility with excellent organisational skills and a passion for coaching others, creating an environment where individuals thrive and operational improvements are successfully embedded into routine laboratory practice.\nSuccess in this role will be measured by your ability to deliver high-quality scientific data whilst maintaining efficient laboratory throughput, developing an engaged and capable team, and ensuring projects progress smoothly through the High Throughput Laboratory.\nKey Responsibilities\nLaboratory Delivery\nCoordinate day-to-day laboratory execution across multiple disease programmes, ensuring samples progress efficiently through Histology, Flow Cytometry, Molecular Biology and Scientific Sample Management workflows.\nTranslate project priorities into detailed laboratory work plans and schedules ensuring resources, equipment and personnel are effectively allocated to deliver programme milestones.\nPartner closely with Disease Project teams, the Head of High Throughput Laboratory, scientific manager peers and Research Project Management to prioritise work, manage competing demands and resolve operational bottlenecks.\nMonitor laboratory throughput, turnaround times, sample progression and resource utilisation, proactively identifying risks to delivery and implementing corrective actions.\nMaintain clear visibility of sample status throughout the laboratory workflow, ensuring timely communication of progress, risks and delays to project teams.\nPeople Leadership\nLine manage and develop direct reports through coaching, regular feedback and performance management.\nPromote a culture of accountability, collaboration and continuous learning within the laboratory team.\nSupport recruitment, onboarding, training and competency assessment of laboratory staff.\nEnsure appropriate laboratory cover and resource planning to support changing portfolio demands.\nScientific Delivery\nRemain scientifically hands-on where required, supporting laboratory activities and troubleshooting technical issues to maintain programme delivery.\nProvide technical oversight across Histology, Flow Cytometry and Molecular Biology workflows, ensuring high standards of scientific quality and reproducibility.\nSupport implementation and operational adoption of new laboratory processes, technologies and workflow improvements in partnership with Assay Development and Automation.\nWork closely with scientific leaders to understand future project requirements and ensure laboratory readiness to support programme delivery.\nLaboratory workflows supported by the team include:\nHistology: Tissue fixation, embedding, sectioning, histochemistry (H&E, IHC) and slide preparation.\nFlow Cytometry: Tissue dissociation, FACS/FANS, cell and nuclei counting, immunostaining and sample preparation.\nMolecular Biology: DNA/RNA extraction, nucleic acid quality assessment, library preparation and sequencing submissions.\nLaboratory Operations & Compliance\nEnsure laboratory activities comply with HTA requirements, COSHH regulations, quality systems and internal laboratory procedures.\nMaintain accurate sample tracking and laboratory records using ELN/LIMS systems, ensuring traceability throughout the sample lifecycle.\nMonitor laboratory KPIs, including throughput, turnaround time, quality and resource utilisation, using data to drive continuous improvement.\nBuild strong working relationships across Research, Project Management, Discovery Partnerships and supporting operational functions.\nQualifications\nYou are an experienced laboratory scientist with a passion for leading people and coordinating complex laboratory operations. You enjoy balancing multiple priorities, developing others and ensuring high-quality science is delivered efficiently within a collaborative matrix environment.\nEssential\nBachelor's degree with significant relevant industry experience (typically 6+ years). MSc or PhD considered in combination with appropriate hands-on laboratory leadership experience.\nExperience working within high-throughput laboratory environments and/or rapidly scaling biotechnology organisations, with the flexibility to adapt to changing priorities while maintaining high standards of scientific quality and operational delivery.\nDemonstrated experience coordinating laboratory workflows across multiple concurrent scientific projects.\nExperience line managing or mentoring laboratory users.\nHands-on expertise in a range of skills across Histology, Flow Cytometry and/or Molecular Biology.\nFamiliarity with ELN and/or LIMS systems for laboratory documentation and sample tracking.\nBroad understanding of tissue and cell biology, genomics and molecular biology workflows.\nDemonstrated ability to coordinate competing priorities whilst maintaining scientific quality and delivery timelines.\nStrong organisational, communication and stakeholder management skills.\nExcellent attention to detail and commitment to scientific quality, safety and compliance.\nDesirable\nExperience supporting HTA-licensed activities and Human Tissue Act compliance.\nExperience with spatial transcriptomics or other advanced genomics technologies.\nExperience working collaboratively with laboratory automation teams to implement workflow improvements.\nExperience supporting implementation of new laboratory technologies or workflow improvements.\nKnowledge of Lean, Operational Excellence or continuous improvement methodologies.\nValues and Behaviours\nEncourage respectful disagreement and cultivate open-minded, ego-free interactions that continuously improve scientific thinking and execution.\nSeek diverse perspectives, practice active listening and ensure every contribution is valued.\nRecognise the impact of your behaviour, communication and leadership style, fostering trust, accountability and collaboration.\nDemonstrate a Quotient-first mindset, balancing project delivery, laboratory priorities and organisational goals.\nChallenge convention thoughtfully, embrace change and continuously seek better ways of delivering science.\nThis is an exciting opportunity to play a pivotal role in the delivery of Quotient's research portfolio, leading a high-performing laboratory team that enables exceptional science through operational excellence, collaboration and continuous improvement.\nRecruitment & Staffing Agencies:\nQuotient Therapeutics (“Quotient”) and Flagship Pioneering (“FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Quotient, FSP or their employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.\nPrivacy Notice for Applicants: When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact .","description_format":"text","description_chars":8853,"description_truncated":false,"requirements":{"experience_years_min":6,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Continuous learning"],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Venture Capital"],"lifecycle":[{"event":"open","at":"2026-10-09T15:26:54Z"}],"visa":[{"country":"GB","licensed_sponsor":true,"evidence":"Licensed UK visa sponsor (Skilled Worker, Senior or Specialist Worker)","filings_12m":null,"filings_prev_12m":null,"green_card_filings_12m":null,"median_offered_wage_usd":null,"route":"Skilled Worker; Global Business Mobility: Senior or Specialist Worker","cap_exempt":false,"checked_at":"2026-10-31T06:23:40+00:00","sources":["UK Home Office: register of licensed sponsors (workers)"],"filings_for_role_12m":0}],"liveness":{"score":81,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.901,"p_room":0.9,"age_days":23,"expected_fill_days":61,"reasons":["conf:1","velocity","win:mid"],"computed_at":"2026-11-02T06:13:15Z"},"pay":null,"html_url":"https://alion.io/job/flagship-pioneering-scientific-manager-high-throughput-laboratory","json_url":"https://alion.io/job/flagship-pioneering-scientific-manager-high-throughput-laboratory.json","meta":{"generated_at":"2026-11-02T09:39:23Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":13560,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":8393},"rest":"https://alion.io/mcp/rest/get_company?id=8393"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fflagship-pioneering-scientific-manager-high-throughput-laboratory"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fflagship-pioneering-scientific-manager-high-throughput-laboratory"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fflagship-pioneering-scientific-manager-high-throughput-laboratory"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/flagship-pioneering-scientific-manager-high-throughput-laboratory\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fflagship-pioneering-scientific-manager-high-throughput-laboratory"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":2183272}},{"tool":"search_jobs","arguments":{"company":"flagshippioneering.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":2183272},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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