368,611open jobs
9,439companies
50,719added this week
Browse all
Salary
$127k – $206k per year
Location
In office (Boulder)
Seniority
Senior · 5+ years exp
Overview
Company
Impact
Profile match
Flagship Pioneering is a life sciences venture creation and platform investment firm headquartered in Cambridge, Massachusetts. Founded in 2000 by CEO Noubar Afeyan, the firm operates on a novel institutional innovation model where it acts as a principal founder, funder, and operator of first-in-category biotechnology and sustainability companies.

COMPANY DESCRIPTION

Flagship Pioneering is a bioplatform innovation company that invents and builds companies that change the world. We bring together the greatest scientific minds with entrepreneurial company builders and assemble the capital to allow them to take courageous leaps. Those big leaps in human health, sustainability and beyond exponentially accelerate scientific progress in areas ranging from disease detection and treatment and nature-positive agriculture to novel applications of AI that are driving the creation of new technologies.   

What sets Flagship apart is our ability to advance science and technology by uniting innovation, company creation, and capital investment under one roof in a way that is largely without precedent. Our scientific founders, entrepreneurial leaders, and professional capital managers are each aligned around an institutionalized process that enables us to innovate and transform for the benefit of people and planet.   

Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. 

THE ROLE

We are seeking a Senior Machine Learning Scientist, Climate and Hydrology to lead the scientific direction and machine learning development for hydrology-aware climate modeling within our broader environmental modeling platform.

This role sits at the intersection of hydrology, weather and climate science, and large-scale machine learning. The Sr. Scientist will help shape how hydrologic process understanding, climate data, and modern ML methods are brought together in next-generation prediction systems, with emphasis on scientifically grounded model development and evaluation.

The individual in this role will work across science, ML, engineering, and data teams to define research priorities, guide model training and benchmarking, build reproducible workflows, and translate scientific insight into scalable model development. This is a cross-functional role requiring strong technical depth, structured scientific thinking, and the ability to move between foundational research and applied execution.

KEY RESPONSIBILITIES

  • Lead scientific and technical efforts at the intersection of hydrology, climate science, and machine learning.
  • Help define research priorities, modeling directions, and evaluation strategies for next-generation climate and environmental prediction systems.
  • Contribute to the development and improvement of ML-based modeling approaches informed by physical and Earth system science.
  • Work with large-scale climate, weather, hydrology, and remote sensing datasets to support model development and scientific analysis.
  • Build and oversee reproducible workflows for data processing, model training, benchmarking, and validation.
  • Collaborate closely with research, engineering, and data teams to translate scientific goals into scalable technical execution.
  • Guide assessment of model performance, uncertainty, and scientific robustness across a range of environmental conditions and applications.
  • Communicate findings through internal reviews, external collaborations, publications, and technical presentations.
  • Help shape the broader scientific roadmap and contribute to team growth and cross-functional leadership.

PROFESSIONAL EXPERIENCE & QUALIFICATIONS 

  • PhD in machine learning, computational science, Earth science, atmospheric science, hydrology, AI, computer science, or a related quantitative discipline.
  • 5+ years of postdoctoral, industry, or applied research experience in climate ML, weather ML, hydrologic modeling, Earth system modeling, or a closely related field.
  • Demonstrated experience with ML-accelerated weather, climate, or hydrology models, with a strong publication track record in the area.
  • Experience working with large climate datasets, including reanalysis products, remote sensing datasets, observational datasets, and model output.
  • Experience with the computational infrastructure required to manage, preprocess, and train on large-scale climate datasets, preferably in the AWS ecosystem.
  • Strong programming skills in Python and experience with modern ML frameworks such as PyTorch
  • Background in scientific ML, spatiotemporal modeling, data assimilation, hybrid physics-ML methods, or related approaches is strongly preferred.
  • Ability to design rigorous evaluation frameworks, performance metrics, and benchmarking approaches for environmental prediction systems.
  • Strong technical writing and communication skills, including reports, presentations, and peer-reviewed publications.
  • Demonstrated ability to work independently in fast-paced, ambiguous environments while collaborating effectively across disciplines.
  • Experience leading cross-functional scientific efforts, mentoring researchers, or helping define research roadmaps is preferred.

LOCATION: Cambridge, MA or Boulder, CO (some travel to Cambridge, MA based headquarters if working from Colorado)

ABOUT FLAGSHIP PIONEERING:

Flagship Pioneering invents and builds platform companies, each with the potential for multiple products that transform human health, sustainability and beyond. Since its launch in 2000, Flagship has originated more than 100 companies. Many of these companies have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  

At Flagship, we accept impossible missions to enable bigger leaps. Our core values guide us through uncertainty and toward lasting impact.

We are an equal opportunity employer. All qualified applicants will be considered for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other characteristic protected by law.

We recognize that great candidates often bring unique strengths without fulfilling every qualification. If you have some of the experience listed above but not all, please apply anyway. We are dedicated to building diverse and inclusive teams and look forward to learning more about your backgroundand interest in Flagship.

Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto.

The salary ranges for this role are $127,000 - $205,900 (Colorado) and $168,000 - $231,000 (Massachusetts). Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Protocos currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Protoco's good faith estimate as of the date of publication and may be modified in the future.

Privacy Notice for Applicants:  When you apply for a role at Flagship Pioneering or one of its portfolio companies, we collect and use personal information you provide (such as your name, contact details, work history, and application materials) to evaluate your application, communicate with you, and comply with legal obligations. Your application data is processed through Greenhouse, our applicant tracking system, and may also be reviewed using AI-assisted screening tools. We do not sell your personal information. California residents have rights under the CCPA/CPRA including to know, delete, and opt out of the sharing of their personal information. If you are located in the EU or UK, we process your data under GDPR and you have rights to access, rectify, and erase your data. To exercise your rights or for questions, contact [email protected]

Free account
Stop reading job ads. Get the ones that fit.
One free account turns this page into a shortlist built around your stack, your level and your pay.
Match on every job. Stack, seniority, pay and location, scored against your profile.
368,611 open roles. Read straight off company career pages, refreshed every day.
Unlimited applications. Every one you send is tracked in one place, on-site or on a company board.
3 tailored CVs a month. Rewritten for the exact job you are applying to. Included free.
Create a free account
Free forever. No card. Under a minute.

Your match

How well do you fit this role?
Two answers are enough for a real match. No account needed.
Check my fit
Answers stay in this browser until you create an account.

Recommended for you based on this role

Similar stack
Same company
Boulder
$29k – $76k per year (Estimated) • In office • 6+ years exp • Bengaluru
C++
Java
Python
Scala
Databases
Databricks
DevOps
AIOps
AWS
Azure
Docker
FinOps
GCP
Kubernetes
Apply
ML Engineer 2 days ago
$17k – $49k per year (Estimated) • Remote • Moscow
Python
SQL
Python
pySpark
AI/ML
CatBoost
LightGBM
MLFlow
Optuna
Pandas
PyTorch
Scikit-learn
TensorFlow
XGBoost
Spark
DevOps
Docker
Kubernetes
Yandex Cloud
Apply
$20k – $51k per year (Estimated) • In office • Omsk
PowerShell
Python
Cybersecurity
MITRE ATT&CK
Apply
$35k – $49k per year • Remote • Moscow
C++
Python
SQL
Databases
Apache Kafka
ClickHouse
PostgreSQL
RabbitMQ
DevOps
Bitbucket
GitHub
Apply
$20k – $41k per year (Estimated) • Remote • 3+ years exp • Moscow
JavaScript
Python
SQL
Python
Django
FastAPI
Databases
PostgreSQL
Frontend
React.js
Vue.js
DevOps
CI/CD
Git
Rest API
Apply
$132k – $209k per year • In office • 6+ years exp • Bachelor's Degree • Somerville
AI/ML
Fine-tuning
LLM
Multimodal AI
NLP
AI Agents
Function Calling
DevOps
AWS
GCP
Cybersecurity
GDPR
Apply
$115k – $165k per year • In office • 3+ years exp • Master's Degree • Cambridge
Python
AI/ML
Time Series Forecasting
Cybersecurity
GDPR
Apply
$213k – $281k per year • In office • 12+ years exp • PhD • Cambridge
Cybersecurity
GDPR
Apply
$176k – $294k per year • In office • 10+ years exp • PhD • Cambridge
Cybersecurity
GDPR
Apply
$172k – $281k per year • In office • 8+ years exp • Cambridge
Cybersecurity
GDPR
Apply
$169k – $253k per year • Equity • In office • Full-Time • 8+ years exp • Bachelor's Degree • Boulder
JavaScript
TypeScript
AI/ML
AI Agents
Frontend
GraphQL
React.js
DevOps
AWS
Azure
GCP
Google GKE
Helm
Kubernetes
Apply
$140k – $200k per year • In office • Boulder
Java
Kotlin
Mobile
Kotlin Multiplatform
DevOps
GCP
Apply
$140k – $200k per year • In office • PhD • Boulder
Swift
AI/ML
Text-to-Speech
Mobile
Fastlane
SwiftUI
DevOps
CI/CD
Git
Vercel
Apply
$152k – $228k per year • Equity • In office • Full-Time • 8+ years exp • Bachelor's Degree • Atlanta • Boulder • Reston
Cybersecurity
Exabeam
MITRE ATT&CK
Apply
$99k – $149k per year • Equity • In office • Full-Time • 4+ years exp • High School Diploma • Boulder
Cybersecurity
CAPA
Apply
See all jobs
This is one of many
368,611 more open roles from verified company boards, updated every day.