{"id":413460,"url":"https://alion.io/job/freenome-staff-computational-biologist-2","title":"Staff Computational Biologist","company":{"id":3761,"name":"Freenome","domain":"freenome.com","url":"https://alion.io/company/freenome","size_band":"201-500","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Greenhouse","truth_index":{"grade":"B","score":74,"open_postings":7,"ghost_share":0,"stale_share":0.857,"repost_share":0,"time_to_fill_p50_days":62,"computed_at":"2026-11-02T06:13:15Z"}},"role":"Biotech","role_family":"Biotech","seniority":"staff","employment_type":null,"work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"posting_text","remote_working_hours":null,"hiring_geo_confidence":"inferred","locations":[],"countries":[],"hiring_countries":["US"],"hiring_countries_total":1,"salary":{"min":188275,"max":270375,"currency":"USD","period":"year","gross":null,"usd_annual":270375},"salary_estimate":null,"experience_years_min":8,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"C++","optional":false},{"name":"Machine Learning","optional":false},{"name":"Matplotlib","optional":false},{"name":"NumPy","optional":false},{"name":"Pandas","optional":false},{"name":"Python","optional":false},{"name":"PyTorch","optional":false},{"name":"Scikit-learn","optional":false},{"name":"TensorFlow","optional":false},{"name":"TensorFlow C++","optional":false}],"status":"live","first_seen_at":"2026-07-23T00:26:24Z","employer_posted_date":"2026-07-23","last_verified_at":"2026-11-02T09:59:41Z","board_verified":true,"closed_at":null,"days_open":102,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":102},"description":"About this opportunity: \n\nAt Freenome, we are seeking a seasoned Staff Computational Biologist to help grow the Freenome Computational Science team. The ideal candidate is an expert in computational biology, genomics, and modeling, with a proven track record in industry settings. In this role, you will apply your background in computational biology and statistics to drive the creation of new applications and enhance algorithms for identifying molecular signatures of cancer. You will collaborate closely with machine learning scientists and computational biologists to iteratively advance computational models and assays, playing a key role in bringing products to the clinic. By joining us, you will have a significant impact on the continued growth of an organization dedicated to changing the entire landscape of cancer.\nThe role reports to the Manager and Staff Computational Biologist leading genomics modeling within Computational Science. This position can be onsite, hybrid, or remote (US only), based out of our campus in Brisbane, California.\nWhat you’ll do:\nServe as a key thought-leader on the Computational Science team, leading the analysis and interpretation of cancer's molecular signatures and staying current with the field.\nGuide and contribute to the development of models that characterize biological changes associated with cancer.\nExecute rigorous computational analyses on data from best-in-class molecular assays, including whole genome sequencing, whole genome bisulfite sequencing, targeted sequencing, RNA sequencing, and protein quantitation.\nDesign novel statistical models for the evaluation, characterization, and modeling of these data types within the context of cancer biology and progression.\nIdentify research hypotheses and potential areas for model improvement; plan, scope, and execute associated research projects with a skilled team of computational biologists.\nSolve complex analytical challenges inherent to the study of cell-free circulating nucleic acids and proteins.\nPartner closely with molecular biologists to collaboratively refine wet lab experiments, and with development scientists to turn research models into products.\nSupport the professional development and career growth of talented, cross-functional computational biologists within your team.\nMust haves:\nPhD or equivalent experience in a relevant quantitative field (e.g., computational biology, cancer biology, statistics, bioinformatics).\nAt least 8 years of post-PhD experience applying computational techniques for biological discovery and product development, preferably in cancer or diagnostics within an industry setting.\nDeep expertise in cancer and molecular biology, with a proven ability to leverage this knowledge for computational biology and diagnostics problems in cancer.\nExtensive experience analyzing data and developing models for high-throughput, quantitative technologies in genomics, epigenomics, transcriptomics, proteomics, (e.g., Methyl-seq, ATAC-seq, RNA-seq, Hi-C, immunodetection assays).\nProficiency in computational and programming skills, including extensive experience with Python statistical packages (Numpy, Matplotlib, Pandas) and modeling packages (Scikit-learn, TensorFlow, PyTorch) or equivalents in languages like R or C/C++.\nNice to haves:\nExperience training, evaluating, or applying biological sequence models-specifically sequence-to-function models that learn and predict functional biology directly from raw DNA, RNA, or protein sequences. \nExperience developing or applying single-cell genomic or transcriptomic models to translate biological heterogeneity into generalizable regulatory or epigenomic signatures. \nExperience modeling cell-free DNA (cfDNA) signals specifically for early disease detection and diagnostic applications.\nBenefits and additional information:\nThe US target range of ourbase salary ratefor new hires is $188,275 - $270,375. You will also be eligible to receive equity, cash bonuses, and a full range of medical, financial, and other benefits depending on the position offered. Please note that individual total compensation for this position will be determined at the Company’s sole discretion and may vary based on several factors, including but not limited to, location, skill level, years and depth of relevant experience, and education. We invite you to check out our career page @ freenome.com/job-openings/ for additional company information. \nFreenome is proud to be an equal-opportunity employer, and we value diversity. Freenome does not discriminate on the basis of race, color, religion, marital status, age, national origin, ancestry, physical or mental disability, medical condition, pregnancy, genetic information, gender, sexual orientation, gender identity or expression, veteran status, or any other status protected under federal, state, or local law.\nApplicants have rights under Federal Employment Laws. \n Family & Medical Leave Act (FMLA)\n Equal Employment Opportunity (EEO)\n Employee Polygraph Protection Act (EPPA)\nCalifornia applicants please review the CCPA Notice at Collection here:\n California Consumer Privacy Act (CCPA)\n#LI-REMOTE","description_format":"text","description_chars":5148,"description_truncated":false,"requirements":{"experience_years_min":8,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Equity","Professional development"],"hiring_locations":[{"name":"United States","iso":"US","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Bioinformatics","Molecular Diagnostics","Precision Medicine","Medical AI"],"lifecycle":[{"event":"open","at":"2026-09-06T02:24:32Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 7 · green card filings: 2","filings_12m":7,"filings_prev_12m":6,"green_card_filings_12m":2,"median_offered_wage_usd":136389,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":31,"band":"fade","label":"Fading","p_open":1,"p_active":0.86,"p_room":0.36,"age_days":102,"expected_fill_days":62,"reasons":["conf:0","win:tail","crowd:"],"computed_at":"2026-11-02T06:13:15Z"},"pay":{"stated_usd_annual":270375,"is_top_pay":true},"html_url":"https://alion.io/job/freenome-staff-computational-biologist-2","json_url":"https://alion.io/job/freenome-staff-computational-biologist-2.json","meta":{"generated_at":"2026-11-02T13:29:58Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":18412,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-03T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":3761},"rest":"https://alion.io/mcp/rest/get_company?id=3761"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Ffreenome-staff-computational-biologist-2"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Ffreenome-staff-computational-biologist-2"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Ffreenome-staff-computational-biologist-2"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/freenome-staff-computational-biologist-2\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Ffreenome-staff-computational-biologist-2"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":413460}},{"tool":"search_jobs","arguments":{"company":"freenome.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":413460},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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