{"id":3624479,"url":"https://alion.io/job/genentech-portfolio-operations-manager","title":"Portfolio Operations Manager","company":{"id":1757810,"name":"Genentech","domain":"gene.com","url":"https://alion.io/company/gene-com","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":82,"open_postings":39,"ghost_share":0,"stale_share":0.923,"repost_share":0,"time_to_fill_p50_days":17,"computed_at":"2026-11-07T05:47:08Z"}},"role":"Management","role_family":"Management","seniority":null,"employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":142200,"max":264200,"currency":"USD","period":"year","gross":null,"usd_annual":264200},"salary_estimate":null,"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-11-02T19:28:18Z","employer_posted_date":"2026-11-02","last_verified_at":"2026-11-07T19:08:58Z","board_verified":true,"closed_at":null,"days_open":5,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":5},"description":"From the beginning, Genentech has been a team of highly dedicated, passionate individuals. We are a place where people are united around a single purpose and an ambitious vision. Together, we aspire to deliver ever better health outcomes for patients while lowering overall healthcare costs. Our goal is to compel the customer to act on behalf of their patients while showing great commitment to the rare disease community, whose support is key. Utilizing innovative methods to identify patients who may benefit from treatment, we must take a highly strategic approach to patient access while assisting patients and their caregivers to navigate the healthcare system.\nPOSITION SUMMARY\nThe Portfolio Operations Manager is responsible for the operating system that allows CE to evaluate, prioritize, sequence, and govern enterprise work as one portfolio. This role owns intake of proposed enterprise work, the prioritized CE portfolio roadmap, governance and decision cadence, and the integrated view of dependencies, duplication, capacity, and tradeoffs. The manager partners with CE Leadership, Enterprise Operations, Regions, HEDs, RBO teams, and other stakeholders to ensure the organization focuses resources on the work that matters most and can make transparent portfolio decisions when priorities compete.\nSCOPE & KEY RESPONSIBILITIES\nEnterprise Portfolio Strategy & Roadmap\nMaintain the integrated CE enterprise portfolio across initiatives, launches, RBO work, and field-partner commitments.\nTranslate CE strategy and leadership priorities into a prioritized portfolio roadmap.\nCreate visibility to timing, sequencing, interdependencies, and major portfolio milestones.\nIdentify duplication, overlap, and opportunities to combine or simplify work across the portfolio.\nEnsure portfolio views are current, decision-oriented, and useful to CE Leadership and operating teams.\nIntake, Evaluation & Prioritization\nOwn the intake and evaluation process for proposed enterprise work.\nEstablish clear criteria for strategic alignment, impact, urgency, effort, capacity, and enterprise value.\nFacilitate prioritization discussions and develop recommendations when demand exceeds available capacity.\nEnsure new work has a clear sponsor, problem statement, intended outcome, and required decision before entering the portfolio.\nRoute approved work to the appropriate Enterprise Operations manager, lead, or enabling team for execution.\nPortfolio Governance & Decision Support\nManage the portfolio governance cadence and prepare decision materials for CE Leadership and CELT as needed.\nCreate transparent decision logs, escalation paths, and follow-through on portfolio choices.\nProvide concise synthesis of what is changing, why it matters, and what decisions or tradeoffs are required.\nEnsure governance focuses on material decisions, risks, and dependencies rather than routine status reporting.\nPartner with initiative and launch teams to maintain accurate portfolio status and milestone visibility.\nCapacity, Dependencies & RBO Integration\nMaintain an integrated view of enterprise capacity, demand, major dependencies, and resource constraints.\nDevelop capacity, sequencing, and tradeoff recommendations across competing priorities.\nIntegrate RBO work into the broader CE portfolio view so Regional and HED-supported commitments are visible and prioritized.\nSurface cross-portfolio risks and constraints early enough to enable leadership action.\nPartner with Enterprise Initiatives and Launch Operations to resolve conflicts and coordinate shared resources.\nTeam Leadership & Portfolio Discipline\nLead, coach, and develop Enterprise Operations Leads assigned to portfolio and RBO work.\nSet standards for portfolio data quality, governance materials, decision support, and milestone tracking.\nAllocate team capacity to the highest-priority portfolio needs and time-sensitive decisions.\nBuild strong portfolio management capabilities, tools, and ways of working across the team.\nContribute to common Enterprise Operations standards, talent practices, and continuous improvement.\nKEY DELIVERABLES\nPrioritized CE enterprise portfolio roadmap\nEnterprise intake and evaluation process\nPortfolio governance calendar and decision materials\nCapacity, sequencing, and tradeoff recommendations\nIntegrated dependency, risk, and milestone view\nRBO portfolio and commitment visibility\nExecutive portfolio dashboards and outcome reviews\nPortfolio standards, templates, and decision logs\nMINDSET & CAPABILITIES\nEnterprise thinker who prioritizes the whole over individual workstreams\nStrong judgment on value, urgency, effort, and tradeoffs\nAble to turn complexity into transparent portfolio choices\nAnalytical and comfortable synthesizing imperfect information\nStrong facilitator of senior-level prioritization and decision discussions\nSkilled at influencing without formal authority\nDisciplined about governance without creating unnecessary bureaucracy\nProactive in identifying capacity constraints, dependencies, and duplication\nStrong communication and executive synthesis capabilities\nCollaborative people leader and developer of talent\nStrong drive for results with an enterprise and customer mindset\nREQUIRED QUALIFICATIONS\nBachelor's degree required\n8-10 years of pharmaceutical, biotechnology, consulting, commercial, portfolio, strategy, program management, and/or operations experience including leading, coaching or mentoring others strongly preferred\nDemonstrated experience with portfolio management, prioritization, governance, or resource planning\nExperience facilitating senior leadership decisions involving competing priorities and tradeoffs\nStrong analytical, synthesis, and project/program management capabilities\nDemonstrated ability to influence across a complex matrixed organization\nStrong communication and executive presentation skills\nAbility and willingness to travel as required for internal and external business meetings\nPREFERRED QUALIFICATIONS\nGraduate-level degree (e.g., MBA or advanced life sciences degree)\nPrior commercial operations, portfolio management, strategy, or transformation experience\nExperience supporting large-scale field organizations, RBO, or enterprise planning processes\nLocation: This position can be based in SSF or Remote. Relocation benefits are not available.\nThe expected salary range for this position based on the primary location of CA is $142,200 - $264,200 USD Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.\nBenefits\nGenentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.\nIf you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.","description_format":"text","description_chars":7354,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":true,"industries":["Drug Discovery","Biologics & Biosimilars","Oncology Therapeutics","Neurology & CNS Therapeutics"],"lifecycle":[{"event":"open","at":"2026-11-02T19:28:18Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 188 · green card filings: 34","filings_12m":188,"filings_prev_12m":151,"green_card_filings_12m":34,"median_offered_wage_usd":150788,"route":null,"cap_exempt":false,"checked_at":"2026-11-07T07:57:00+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":62,"band":"ok","label":"Likely open","p_open":1,"p_active":0.622,"p_room":1,"age_days":4,"expected_fill_days":17,"reasons":["conf:2","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-11-07T05:47:08Z"},"pay":{"stated_usd_annual":264200,"is_top_pay":true},"html_url":"https://alion.io/job/genentech-portfolio-operations-manager","json_url":"https://alion.io/job/genentech-portfolio-operations-manager.json","meta":{"generated_at":"2026-11-08T05:22:23Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":11682,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-09T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1757810},"rest":"https://alion.io/mcp/rest/get_company?id=1757810"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgenentech-portfolio-operations-manager"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgenentech-portfolio-operations-manager"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgenentech-portfolio-operations-manager"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/genentech-portfolio-operations-manager\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgenentech-portfolio-operations-manager"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3624479}},{"tool":"search_jobs","arguments":{"company":"gene.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3624479},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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