{"id":3314585,"url":"https://alion.io/job/genentech-scientist-3-cell-therapy-t-cell-differentiation","title":"Scientist 3, Cell Therapy T cell Differentiation","company":{"id":1757810,"name":"Genentech","domain":"gene.com","url":"https://alion.io/company/gene-com","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":80,"open_postings":25,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":21,"computed_at":"2026-10-30T05:48:23Z"}},"role":"Biotech","role_family":"Biotech","seniority":"middle","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":103400,"max":192000,"currency":"USD","period":"year","gross":null,"usd_annual":192000},"salary_estimate":null,"experience_years_min":3,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"CRISPR","optional":false},{"name":"Design of Experiments","optional":false}],"status":"live","first_seen_at":"2026-10-26T00:00:00Z","employer_posted_date":"2026-10-26","last_verified_at":"2026-10-30T20:53:20Z","board_verified":true,"closed_at":null,"days_open":4,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":4},"description":"Bold thinkers, breakthrough makers: Join a team of curious minds who challenge the status quo, create what’s next in science and technology, and have the freedom to turn daring ideas into real breakthroughs.\nThe Opportunity\nThe Cell Therapy department within Genentech Research and Early Development (gRED) is seeking a motivated, collaborative Scientist 3 to advance next-generation, off-the-shelf cell therapies for patients with intractable diseases. Reporting to a Principal Fellow, you will play a pivotal role in shaping our iPSC-to-T cell differentiation platform, directly influencing pipeline programs and mechanistic biology discoveries.\nDevelop, optimize, and implement robust iPSC-to-T cell differentiation protocols in the context of diverse therapeutic programs.\nInvestigate cellular and molecular mechanisms underlying T-cell lineage specification, differentiation efficiency, and maturation to drive process enhancements.\nTranslate biological discoveries into tangible improvements in cell-product quality, yield, phenotype, and function.\nAnalyze complex, multidimensional datasets to draw incisive conclusions and guide subsequent experimental strategies.\nCollaborate cross-functionally with research, translational, computational, process development, and external partner groups across gRED.\nContribute to scientific and strategic planning for the Cell Therapy department and Genentech’s broader therapeutic pipeline.\nWho you are\nPhD in Immunology, Stem Cell Biology, Cell & Molecular Biology, or related field with at least 3 years of relevant experience.\nExtensive hands-on experience differentiating iPSCs to T cell and/or other immune cell lineages.\nStrong cell and molecular biology background with a demonstrated ability to apply mechanistic approaches to investigate cell fate decisions.\nProven track record of evaluating and optimizing the robustness, consistency, and reproducibility of stem cell differentiation platforms.\nDeep experience developing and applying phenotypic and functional assays to characterize T cell activity, fitness, and potency.\nStrong organizational, written, and verbal communication skills with a demonstrated history of collaborative delivery across multidisciplinary teams.\nPreferred\nExperience with Design of Experiments (DOE), high-throughput screening, or other quantitative multivariate process-optimization methodologies.\nPrior experience in cell therapy or drug development, understanding critical quality attributes (identity, purity, yield, viability, and potency).\nHands-on expertise with CRISPR/Cas9 or other genome-engineering modalities in stem cells (iPSCs).\nDemonstrated record of scientific impact through high-impact publications, patents, or contributions to therapeutic advancement.\nLocation\nThis is a lab-based role at our South San Francisco, CA campus. Onsite presence is required.\nRelocation benefits are available for this job posting.\nThe expected salary range for this position based on the primary location of CA is $103,400 - $192,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.\nBenefits\nGenentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.\nIf you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.","description_format":"text","description_chars":3950,"description_truncated":false,"requirements":{"experience_years_min":3,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":true,"industries":["Cell & Gene Therapy","Regenerative Medicine","Drug Discovery","Neurology & CNS Therapeutics"],"lifecycle":[{"event":"open","at":"2026-10-27T04:39:09Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 188 · green card filings: 34","filings_12m":188,"filings_prev_12m":151,"green_card_filings_12m":34,"median_offered_wage_usd":150788,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.63,"p_room":1,"age_days":4,"expected_fill_days":21,"reasons":["conf:0","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-10-30T05:48:23Z"},"pay":{"stated_usd_annual":192000,"is_top_pay":true},"html_url":"https://alion.io/job/genentech-scientist-3-cell-therapy-t-cell-differentiation","json_url":"https://alion.io/job/genentech-scientist-3-cell-therapy-t-cell-differentiation.json","meta":{"generated_at":"2026-10-30T22:55:09Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":13914,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-31T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1757810},"rest":"https://alion.io/mcp/rest/get_company?id=1757810"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgenentech-scientist-3-cell-therapy-t-cell-differentiation"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgenentech-scientist-3-cell-therapy-t-cell-differentiation"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgenentech-scientist-3-cell-therapy-t-cell-differentiation"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/genentech-scientist-3-cell-therapy-t-cell-differentiation\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgenentech-scientist-3-cell-therapy-t-cell-differentiation"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3314585}},{"tool":"search_jobs","arguments":{"company":"gene.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3314585},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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