{"id":3237064,"url":"https://alion.io/job/genentech-senior-scientist-translational-pkpd","title":"Senior Scientist- Translational PKPD","company":{"id":1757810,"name":"Genentech","domain":"gene.com","url":"https://alion.io/company/gene-com","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":82,"open_postings":31,"ghost_share":0,"stale_share":0.935,"repost_share":0,"time_to_fill_p50_days":21,"computed_at":"2026-10-31T05:58:55Z"}},"role":"Biotech","role_family":"Biotech","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["South San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":120700,"max":224100,"currency":"USD","period":"year","gross":null,"usd_annual":224100},"salary_estimate":null,"experience_years_min":1,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Antibody Engineering","optional":false},{"name":"GLP","optional":false},{"name":"MATLAB","optional":false}],"status":"live","first_seen_at":"2026-10-10T00:00:00Z","employer_posted_date":"2026-10-10","last_verified_at":"2026-10-31T19:49:17Z","board_verified":true,"closed_at":null,"days_open":21,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":21},"description":"Why Genentech\nWe advance science so that we all have more time with the people we love.\nThis opening is for a Senior Scientist position in the translational Pharmacokinetics and Pharmacodynamics (tPKPD) department within the Development Sciences division in Genentech Research and Early Development (gRED) unit.\nThe focus of this position is to support the preclinical pharmacokinetic and pharmacodynamics (PKPD) efforts to guide the design, delivery and development of biologics in the Genentech pipeline. Core responsibilities include providing technical support for the PKPD assessment of drug candidates and marketed products and working independently or under the direct supervision of a Scientist.\nThe Opportunity:\nThe responsibilities of this Senior Scientist position will :\nDesign, conduct, analyze and interpret all in vitro and in vivo ADME and PKPD studies that are necessary to understand the pharmacology of drug candidates in animals and predict their behavior in humans \nPrepare summary tables and reports for non-clinical studies; may prepare documents for regulatory agencies, including INDs and BLAs under the supervision of a Scientist \nPresent data at project teams and department meetings and conferences as appropriate \nPublish innovative PKPD focused research in high quality scientific, technical or medical journals. \nManage an active laboratory program that supports basic research in PKPD and also supports pipeline projects \nCollaborate with other departments such as Clinical Pharmacology, Research, Bioanalytical Sciences, Safety Assessment, PD Biomarker/OMNI, Antibody Engineering, Non-clinical Biostatistics, Regulatory Affairs, Technical Development, and others\nParticipate in compliance and safety related activities. Perform other duties, as assigned \nWho You Are:\nPh.D., or M.D., or PharmD degree or equivalent curriculum in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology or related disciplines is required (experience is specific to job level). Persons without a formal degree who have comparable depth and breadth of training and experience (gained at Genentech or elsewhere), and who meet job-specific criteria, are eligible for consideration\n1-2 years of relevant industry experience in translational PKPD/pharmacology or equivalent Postdoctoral experience is preferred\nOutstanding record of accomplishment in his/her field as evidenced by his/her co authored publications, patents, internal reports and/or regulatory filings.\nStrong knowledge of laboratory techniques and safety is required; Regular GLP and laboratory safety training is required\nExperience in quantitative PKPD software (e.g., WinNonlin, NONMEM, ADAPT II, Matlab, Simbiology, R) \nDemonstrated independent thought and creativity in relevant discipline; independently designs, carries out, analyzes, interprets, and documents studies and experiments.\nGood communication skills, independently presents at department and project team meeting \nThe expected salary range for this position based on the primary location of San Franscico, CA is $ 120,700 - $224,100Annual. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.\nThis position also qualifies for the benefits detailed here:\nBenefits\nRelocation benefits are not available for this posting.\n#LI-PL1\nGenentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.\nIf you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.","description_format":"text","description_chars":4086,"description_truncated":false,"requirements":{"experience_years_min":1,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":[],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":true,"industries":["Biotechnology","Health Care","Care Coordination & Population Health"],"lifecycle":[{"event":"open","at":"2026-10-25T12:44:42Z"}],"visa":[{"country":"US","licensed_sponsor":true,"evidence":"H-1B filings in 12 months: 188 · green card filings: 34","filings_12m":188,"filings_prev_12m":151,"green_card_filings_12m":34,"median_offered_wage_usd":150788,"route":null,"cap_exempt":false,"checked_at":"2026-10-29T16:27:21+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":32,"band":"fade","label":"Fading","p_open":1,"p_active":0.585,"p_room":0.55,"age_days":21,"expected_fill_days":21,"reasons":["conf:4","stale_co","velocity","win:tail","comp:brand"],"computed_at":"2026-10-31T05:58:55Z"},"pay":{"stated_usd_annual":224100,"is_top_pay":true},"html_url":"https://alion.io/job/genentech-senior-scientist-translational-pkpd","json_url":"https://alion.io/job/genentech-senior-scientist-translational-pkpd.json","meta":{"generated_at":"2026-10-31T23:44:06Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":37218,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-01T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1757810},"rest":"https://alion.io/mcp/rest/get_company?id=1757810"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgenentech-senior-scientist-translational-pkpd"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgenentech-senior-scientist-translational-pkpd"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgenentech-senior-scientist-translational-pkpd"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/genentech-senior-scientist-translational-pkpd\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgenentech-senior-scientist-translational-pkpd"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":3237064}},{"tool":"search_jobs","arguments":{"company":"gene.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":3237064},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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