{"id":1953109,"url":"https://alion.io/job/genomics-application-security-engineer","title":"Application Security Engineer","company":{"id":52323,"name":"Genomics","domain":"genomics.com","url":"https://alion.io/company/genomics-com","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"A","score":95,"open_postings":9,"ghost_share":0,"stale_share":0,"repost_share":0,"time_to_fill_p50_days":60,"computed_at":"2026-10-07T05:47:15Z"}},"role":"Security","role_family":"Security","seniority":null,"employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["London, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":75000,"max_usd":164000,"period":"year","method":"role_country_seniority_unknown","sample_n":108},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"Amazon EC2","optional":false},{"name":"Amazon EKS","optional":false},{"name":"Amazon S3","optional":false},{"name":"AWS","optional":false},{"name":"Azure","optional":false},{"name":"CI/CD","optional":false},{"name":"GCP","optional":false},{"name":"Go","optional":false},{"name":"IAM","optional":false},{"name":"Kubernetes","optional":false},{"name":"Least Privilege","optional":false},{"name":"LLM","optional":false},{"name":"LLM Guardrails","optional":false},{"name":"Python","optional":false},{"name":"SIEM","optional":false},{"name":"TypeScript","optional":false}],"status":"live","first_seen_at":"2026-10-06T09:24:40Z","employer_posted_date":"2026-10-06","last_verified_at":"2026-10-08T00:34:48Z","board_verified":true,"closed_at":null,"days_open":1,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":1},"description":"Location: Oxford or London (Hybrid)\nThe Mission: Why We Exist\nGenomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer, healthier lives, using the power of genomics.\nGenomics aims to help people live longer, healthier lives in two ways: super-charging drug discovery and development for novel treatments with our AI-enabled advanced genetic analytics platform, and by helping people understand their personal risk of common chronic diseases through polygenic risk scores - giving doctors and health systems the chance to get the right people into the right prevention, screening and treatment programmes at the right time.\nRole Purpose\nGenomic data is some of the most sensitive data there is, and our customers trust us with it. As Senior Application Security Engineer on Mystra, you'll own application security end-to-end across multi-tenant, trillion-row-scale, AI-enabled data platforms.\nYou'll lead threat modelling and design review with product teams, build the tooling and patterns that make secure codet, and find and fix the vulnerabilities that slip through. You'll do it with security-focused AI tooling, steered by your own expert judgement and intuition, to keep Genomics secure against state-of-the-art threats.\nA Day in the Life\nLeading threat modelling and design reviews for new products and infrastructure, and defining the security invariants every team builds against: tenant isolation, authentication and authorisation, secrets, least privilege, and trust boundaries\n\nBuilding the libraries, patterns, and CI/CD guardrails that make the secure way the easy way, and deciding what is enforced versus advised\n\nBuilding and tuning AI tooling for code analysis, triage, and remediation, and deciding where its output can be trusted and where it must be verified\n\nHunting for vulnerabilities through code review, testing, and proof-of-concept exploits, then running the disclosure programme and driving every finding through to a verified fix\n\nSecuring our agentic and AI surfaces, from prompt injection and tool boundaries to delegated credentials and tenant-scoped access, and proving the controls hold under adversarial testing\n\nWorking as an embedded, trusted partner to product teams, SRE, detection and response, the data platform team, and the MystraAI / ML team, unblocking rather than gating\n\nWho You Are\nExperience within application security in production. You've found and fixed exploitable bugs in software you were responsible for, through threat modelling, secure design, code review, and proof-of-concept exploitation across web services, APIs, and data-serving interfaces. Triaging scanner output doesn't count\n\nProduction-quality software engineering in at least one mainstream language (such as Python, Go, or TypeScript), and you can read several. You've built and operated security or developer tooling in CI/CD pipelines, such as static and dependency analysis, secrets detection, or policy-as-code, and engineers actually adopted it\n\nHands-on depth securing multi-tenant systems on a major cloud. We run on AWS (RDS, EC2, S3, EKS, Batch), and comparable GCP or Azure depth transfers. You know tenant isolation, IAM and least privilege, secrets management, Kubernetes and container security, and the trust boundaries between services\n\nDaily use of frontier AI models for code analysis, vulnerability triage, remediation drafting, and research, with sharp judgement about where they're reliable and where they mislead. You've built or tuned LLM-driven tooling rather than only used a chat interface, and you understand the attack surface it introduces\n\nExperience running, or being core to, a vulnerability disclosure or bug bounty programme and the remediation lifecycle behind it, covering severity, prioritisation, SLAs, root cause, and systemic fixes. You've also worked application-layer incidents alongside detection and response, using security telemetry and SIEM data as evidence\n\nRisk-led judgement. You know which designs need deep review, which findings matter and which are noise, and you make accepted risk explicit so leadership can decide with open eyes\n\nClear communication. You explain risk and trade-offs precisely to engineers, product, and leadership, write guidance people actually use, and mentor others to grow security capability across teams\n\nYour Package\nWe are committed to providing a transparent, supportive, and rewarding work environment.\nCompensation & Growth\nCompetitive Reward: Salaries are externally benchmarked annually to ensure market-aligned compensation.\n\nClear Career Path: A straightforward, open progression framework means you'll always know the path to promotion and how to achieve your next career goal.\n\nContinuous Learning: Including external courses and a wide library of L&D materials, because your growth is our success.\n\nWellbeing & Time Off\nHoliday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.\n\nFinancial & Health Security: Robust benefits including a market-leading pension scheme, comprehensive private health insurance for you and your family with NO excess, critical illness, and life assurance.\n\nEnhanced Leave: Enhanced paid family leave to support all new parents.\n\nWork Environment & Culture\nHybrid Working\n\nTruly Inclusive Time Off: Our 'Bank Your Bank Holiday' program allows you to exchange public holidays for dates that hold personal or cultural significance to you.\n\nVibrant Social Culture: From regular Town Halls and team picnics to organised sports events, our social committee ensures frequent opportunities to connect and celebrate.\n\nGreen Commute: Cycle-to-Work scheme and convenient office locations near major transport hubs.\n\nReady to Build the Future?\nIf this opportunity excites you, apply now!\nWe are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.\nGenomics politely requests no contact from recruitment agencies. We do not accept speculative CVs from recruitment agencies nor accept the fees associated with them.","description_format":"text","description_chars":6464,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Annual leave","Continuous learning","Health insurance","Hybrid work","Parental leave"],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Application Security","Genomics & Genetic Testing","Precision Medicine"],"lifecycle":[{"event":"open","at":"2026-10-06T10:57:31Z"}],"visa":[{"country":"GB","licensed_sponsor":true,"evidence":"Licensed UK visa sponsor (Skilled Worker)","filings_12m":null,"filings_prev_12m":null,"green_card_filings_12m":null,"median_offered_wage_usd":null,"route":"Skilled Worker","cap_exempt":false,"checked_at":"2026-10-07T06:21:01+00:00","sources":["UK Home Office: register of licensed sponsors (workers)"],"filings_for_role_12m":0}],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":0,"expected_fill_days":60,"reasons":["conf:0","win:early"],"computed_at":"2026-10-07T05:47:15Z"},"pay":null,"html_url":"https://alion.io/job/genomics-application-security-engineer","json_url":"https://alion.io/job/genomics-application-security-engineer.json","meta":{"generated_at":"2026-10-08T00:48:27Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler","counted_by":"address","units_charged":1,"used_today":1297,"day_limit":5000,"remaining_today":3703,"minute_limit":60,"resets_at":"2026-10-09T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":52323},"rest":"https://alion.io/mcp/rest/get_company?id=52323"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgenomics-application-security-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgenomics-application-security-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgenomics-application-security-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/genomics-application-security-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgenomics-application-security-engineer"}]}