{"id":142068,"url":"https://alion.io/job/genomics-staff-site-reliability-engineer","title":"Product Engineer","company":{"id":52323,"name":"Genomics","domain":"genomics.com","url":"https://alion.io/company/genomics-com","size_band":"51-200","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Ashby","truth_index":{"grade":"A","score":95,"open_postings":5,"ghost_share":0,"stale_share":0,"repost_share":0,"time_to_fill_p50_days":88,"computed_at":"2026-10-17T05:46:00Z"}},"role":"Backend","role_family":"Backend","seniority":"staff","employment_type":"full_time","work_mode":"hybrid","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["London, United Kingdom"],"countries":["GB"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":157000,"max_usd":270000,"period":"year","method":"role_seniority_country_remote_cell","sample_n":24},"experience_years_min":null,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"AI Agents","optional":false},{"name":"ClickHouse","optional":false},{"name":"Least Privilege","optional":false},{"name":"LLM Guardrails","optional":false},{"name":"Platform Engineering","optional":false},{"name":"Self-Healing","optional":false}],"status":"live","first_seen_at":"2026-08-06T09:22:36Z","employer_posted_date":"2026-09-23","last_verified_at":"2026-10-18T13:46:07Z","board_verified":true,"closed_at":null,"days_open":73,"trust":{"level":"ok","repost_count":0,"flags":[],"days_open":72},"description":"Location: Oxford or London (Hybrid)\nThe Mission: Why We Exist\nGenomics is a science-led transatlantic TechBio combining large-scale genetic and health data with proprietary analytics to accelerate drug discovery and advance predictive, preventative healthcare. We are united by a single vision to help people live longer healthier lives, using the power of genomics.\nGenomics aims to help people live longer, healthier lives in two ways: super-charging drug discovery and development for novel treatments with our AI-enabled advanced genetic analytics platform, and by helping people understand their personal risk of common chronic diseases through polygenic risk scores - giving doctors and health systems the chance to get the right people into the right prevention, screening and treatment programmes at the right time.\nRole Purpose\nGenomics runs on multi-trillion-row, petabyte-scale genetic and health data. Mystra is the analytical data platform that makes that usable, and MystraAI is the agentic layer we're building on top of it. This is a Staff-level role for someone who wants to push the boundaries of what a data platform can do - solving hard, novel infrastructure problems at genuine scale, and setting the technical direction that other teams build on.\nYou'll lead the analytical data platform and our Data-as-a-Service offering, shape the data foundations behind MystraAI, and line-manage a small team of engineers while staying deeply hands-on. If you want your work to sit at the intersection of large-scale systems engineering and genuinely meaningful science, this is it.\nA Day in the Life\nThe role spans the full depth of the platform - from database internals up to the systems that serve data across the product. On any given day you might be:\nPushing multi-tenant ClickHouse (or equivalent OLAP) clusters to their limits at multi-trillion-row, petabyte scale - designing sharding and replication strategies, building materialised views, and solving genuinely hard performance and cost/efficiency problems most engineers never get to touch.\n\nBuilding the tooling and automation that lets data-intensive pipelines scale themselves - smart observability, predictive capacity planning, and systems resilient enough that incidents become rare rather than routine.\n\nShaping Data-as-a-Service as a real product - designing a secure, multi-tenant, immutable release architecture, with data made discoverable at scale through catalogue and ontology-driven search, in partnership with the data team.\n\nPowering agentic AI from the data platform - architecting the data foundations behind MystraAI and designing secure, tenant-scoped access patterns for autonomous agents, partnering closely with the ML team on how our AI systems perform.\n\nTreating security as a design problem, not a checklist - building tenant isolation, credential management and least-privilege access into the architecture from first principles.\n\nSetting technical direction, mentoring engineers, and influencing decisions well beyond your own team.\n\nWho You Are\nYou're a recognised specialist who leads through expertise - principal-level individual-contributor depth combined with the judgement to set standards others follow. You'll bring:\nLarge-scale OLAP / ClickHouse. Deep experience designing and pushing multi-tenant ClickHouse at extreme scale. You engage with the engine at source level rather than as a black box - and ideally have contributed code upstream.\n\nPlatform engineering at scale. You've built self-healing, observable systems for analytical data platforms and pipelines - the kind of engineering that reduces toil rather than manages it.\n\nData-as-a-Service productisation. You think in terms of data as a product: secure, multi-tenant, immutable releases, and discoverability at scale.\n\nAgent-ready data. You understand what it takes to expose platform data to agents safely and at scale - access patterns, tenant isolation, sensible guardrails - and have scaled data infrastructure under demanding workloads.\n\nMulti-tenant security. You design for isolation, least-privilege access and sound secrets management from the outset.\n\nTechnical leadership. You drive direction and innovation across a platform, mentor engineers, and can line-manage a small team without losing your own hands-on edge.\n\nYour Package\nWe are committed to providing a transparent, supportive, and rewarding work environment.\nCompensation & Growth\nCompetitive Salary: Salaries are externally benchmarked annually to ensure top-of-market compensation.\n\nClear Career Path: A straightforward, open progression framework means you'll always know the path to promotion and how to achieve your next career goal.\n\nContinuous Learning: Including external courses and a wide library of L&D materials, because your growth is our success.\n\nWellbeing & Time Off\nHoliday: 25 days annual leave, plus bank holidays, plus an extra 3-day company-wide shutdown at year-end.\n\nFinancial & Health Security: Robust benefits including a market-leading pension scheme, comprehensive private health insurance for you and your family with NO excess, critical illness, and life assurance.\n\nEnhanced Leave: Enhanced paid family leave to support all new parents.\n\nWork Environment & Culture\nFlexible Working: Hybrid Working (e.g., From our London, Oxford Office)\n\nTruly Inclusive Time Off: Our 'Bank Your Bank Holiday' program allows you to exchange public holidays for dates that hold personal or cultural significance to you.\n\nVibrant Social Culture: From regular Town Halls and team picnics to organised sports events, our social committee ensures frequent opportunities to connect and celebrate.\n\nGreen Commute: Cycle-to-Work scheme and convenient office locations near major transport hubs.\n\nReady to Build the Future?\nIf this opportunity excites you, apply now!\nWe are dedicated to creating a diverse environment and are proud to be an equal-opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, or veteran status.\nGenomics politely requests no contact from recruitment agencies. We do not accept speculative CVs from recruitment agencies nor accept the fees associated with them.","description_format":"text","description_chars":6318,"description_truncated":false,"requirements":{"experience_years_min":null,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":false,"languages":[]},"benefits":["Annual leave","Continuous learning","Flexible schedule","Health insurance","Hybrid work","Parental leave"],"hiring_locations":[{"name":"United Kingdom","iso":"GB","kind":"country"}],"hiring_excludes":[],"relocation_offered":false,"industries":["Genomics & Genetic Testing","Precision Medicine"],"lifecycle":[{"event":"open","at":"2026-08-06T09:22:36Z"}],"visa":[{"country":"GB","licensed_sponsor":true,"evidence":"Licensed UK visa sponsor (Skilled Worker)","filings_12m":null,"filings_prev_12m":null,"green_card_filings_12m":null,"median_offered_wage_usd":null,"route":"Skilled Worker","cap_exempt":false,"checked_at":"2026-10-17T06:21:15+00:00","sources":["UK Home Office: register of licensed sponsors (workers)"],"filings_for_role_12m":0}],"liveness":{"score":49,"band":"ok","label":"Likely open","p_open":1,"p_active":0.815,"p_room":0.6,"age_days":71,"expected_fill_days":88,"reasons":["conf:0","win:late","crowd:"],"computed_at":"2026-10-17T05:46:00Z"},"pay":null,"html_url":"https://alion.io/job/genomics-staff-site-reliability-engineer","json_url":"https://alion.io/job/genomics-staff-site-reliability-engineer.json","meta":{"generated_at":"2026-10-18T15:57:08Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":21948,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-10-19T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.02,"usd":0.002,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":52323},"rest":"https://alion.io/mcp/rest/get_company?id=52323"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgenomics-staff-site-reliability-engineer"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":1,"usd":0.1},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgenomics-staff-site-reliability-engineer"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.02,"usd":0.002},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgenomics-staff-site-reliability-engineer"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/genomics-staff-site-reliability-engineer\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgenomics-staff-site-reliability-engineer"}]}