{"id":4102023,"url":"https://alion.io/job/gladstone-institutes-research-engineer-ii-iii","title":"Research Engineer II / III","company":{"id":1818788,"name":"Gladstone Institutes","domain":"gladstone.org","url":"https://alion.io/company/gladstone-org","size_band":"501-1000","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":75,"open_postings":4,"ghost_share":0,"stale_share":1,"repost_share":0,"time_to_fill_p50_days":null,"computed_at":"2026-11-12T10:38:37Z"}},"role":"AI/ML","role_family":"AI/ML","seniority":"middle","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["San Francisco, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":78000,"max":92000,"currency":"USD","period":"year","gross":null,"usd_annual":92000},"salary_estimate":null,"experience_years_min":2,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Cell Culture","optional":false},{"name":"Confocal Microscopy","optional":false},{"name":"Git","optional":false},{"name":"Keras","optional":false},{"name":"Python","optional":false},{"name":"PyTorch","optional":false},{"name":"SLURM","optional":false},{"name":"SQL","optional":false},{"name":"TensorFlow","optional":false}],"status":"live","first_seen_at":"2026-11-11T21:56:05Z","employer_posted_date":"2026-11-11","last_verified_at":"2026-11-12T04:30:40Z","board_verified":true,"closed_at":null,"days_open":0,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":0},"description":"Category:\nScienceLab/Area:\nFinkbeiner LabDescription:\nThe Finkbeiner Lab at the Gladstone Institutes in San Francisco, CA is hiring a Research Engineer (level II or III, depending on experience) to develop, operate and maintain our custom and commercial microscopy systems. You will support the development of our automated imaging platforms, including the newly invented Thinking Microscope and Robo5, help maintain our legacy systems, and build and maintain the image-analysis pipelines and data infrastructure that turn images into results.\nThis is a hands-on role at the intersection of microscopy, computation and cell biology, and you will be a critical member of a team of biologists. Fluency with microscopes, from hardware and optics through acquisition software to the analysis pipeline, is the core of the job. Because our instruments are developed around real biological samples, wet bench and cell culture experience is a strong plus. The ideal candidate is interested in engineering, biology, high-throughput systems, robotics and artificial intelligence, and is comfortable troubleshooting an instrument and writing analysis code, and ideally preparing cells for imaging.\nWhat you will do:\nMicroscopy systems (primary focus)\nSupport the development of the lab's automated, robotic imaging platforms (including the Thinking Microscope and Robo5), covering hardware integration, optical alignment and acquisition software\nOperate, calibrate, maintain and repair the lab's existing and legacy fluorescence microscopes and imaging systems\nTroubleshoot hardware, firmware and software faults and document fixes\nKeep documentation, standard operating procedures and parts inventories current, and train lab members on the instruments\nImage analysis and data\nBuild, run and maintain image-analysis pipelines from raw acquisition through quantification\nOrganize and manage imaging data and metadata, including querying and maintaining databases\nUse AI and machine-learning tools to speed up analysis, automation and day-to-day engineering work\nWet bench\nCulture cells, develop biosensors, and prepare biological samples used to develop, test and validate imaging capabilities, such as multiplexed reporters and hyperspectral imaging\nContribute to ongoing wet bench projects as needed, in support of platform development\nWork with lab scientists to translate biological questions into instrument and analysis requirements\nCollaboration and project management\nPartner with computational and biology colleagues across the lab\nPlan and track your own projects, set realistic timelines and keep stakeholders informed\nCommunicate progress, results and technical trade-offs clearly to a mixed audience\nSupport funder-facing deliverables tied to platform development\nWhat you will need:\nB.S. or higher in biological sciences, engineering, physics, bioengineering, computer science, math or a related field, plus 2 or more years of relevant experience in an academic or industry setting, or equivalent experience; level II or III depending on years of relevant experience\nFluency with fluorescence microscopy hardware: hands-on experience with epifluorescence and/or confocal microscopes, including optical alignment, acquisition software and troubleshooting\nExperience deriving quantitative data from images using automated analysis techniques, and building or maintaining image-analysis pipelines\nProficiency in at least one language used for image analysis and instrument control (for example R, Python, or others)\nComfortable working on the command line and with Git for version control\nInterest in engineering and customizing microscopes, and in developing software to control them\nAbility to troubleshoot and use creativity to solve problems without an established playbook\nExcellent communication skills and ability to work effectively in small groups with scientists who are not engineers\nResponsible, highly organized, independent and self-motivated, able to manage several projects at once with minimal supervision\nWhat is preferred:\nWet bench and cell culture experience (strong plus), including familiarity with the biology behind the experiments; fibroblast or iPSC culture experience is especially helpful\nExperience running analyses on distributed or high-performance computing systems such as Slurm, and with workflow or pipeline tools such as Nextflow\nExperience with robotics, automation, high-content imaging or large-scale image acquisition\nExperience with databases such as SQL for organizing and querying imaging data\nFamiliarity with AI and machine-learning tools, including deep learning frameworks such as TensorFlow, Keras or PyTorch, and with everyday AI productivity tools\nExperience integrating hardware (cameras, stages, light sources, controllers) with software\nExperience with firmware, electronics or CAD for custom instrument parts\nFamiliarity with and interest in neurodegenerative diseases, neuroscience, and cell biology\nSalary Range:\nResearch Engineer II - $78k - $92K\nResearch Engineer III- $89K - $105K\n Gladstone Perks & Benefits\nPeople-work with talented, committed, and supportive teammates within an organization that values each member of its community.\n\nA meaningful place to grow and learn-whether it’s your professional skills or scientific knowledge, we have the resources and environment to advance either so you can better support Gladstone’s mission to drive a new era of discovery in disease-oriented science and to mentor tomorrow’s leaders in an inspiring and excellent environment.\n\nHealthy work/life balance-you are highly engaged and productive at work because you can have time to recharge and enjoy a vibrant life outside of work.\n\nCompensation-competitive salary. Title and salary will be commensurate with education and experience.\n\nExcellent benefits-generous medical, dental, vision, retirement plan, paid vacation, commuter benefits, access to free shuttle transportation.\n\nGladstone is committed to providing equal employment opportunities to all employees and applicants for employment without regard to race, color, sex, religion, national origin, ancestry, age, marital status, medical condition, physical or mental disability, veteran status, sexual orientation, or any other non-job related characteristic. We make all employment decisions so as to further this principle of equal employment.","description_format":"text","description_chars":6361,"description_truncated":false,"requirements":{"experience_years_min":2,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"bachelor","optional":false},"security_clearance":false,"languages":[]},"benefits":["Retirement plans"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Biotechnology","Research Institutes"],"lifecycle":[{"event":"open","at":"2026-11-11T21:56:05Z"}],"visa":[],"liveness":{"score":86,"band":"hot","label":"Hiring now","p_open":1,"p_active":0.86,"p_room":1,"age_days":0,"expected_fill_days":30,"reasons":["conf:6","win:early"],"computed_at":"2026-11-12T10:38:37Z"},"pay":{"stated_usd_annual":92000,"is_top_pay":false},"html_url":"https://alion.io/job/gladstone-institutes-research-engineer-ii-iii","json_url":"https://alion.io/job/gladstone-institutes-research-engineer-ii-iii.json","meta":{"generated_at":"2026-11-12T11:19:24Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":23212,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-13T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":1818788},"rest":"https://alion.io/mcp/rest/get_company?id=1818788"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fgladstone-institutes-research-engineer-ii-iii"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"live","price":{"credits":2,"usd":0.2},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fgladstone-institutes-research-engineer-ii-iii"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fgladstone-institutes-research-engineer-ii-iii"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/gladstone-institutes-research-engineer-ii-iii\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fgladstone-institutes-research-engineer-ii-iii"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":4102023}},{"tool":"search_jobs","arguments":{"company":"gladstone.org","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":4102023},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. 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