{"id":1837502,"url":"https://alion.io/job/glycoera-senior-scientist-upstream-process-development-3","title":"Senior Scientist, Upstream Process Development","company":{"id":677860,"name":"GlycoEra","domain":"glycoera.com","url":"https://alion.io/company/glycoera","size_band":"11-50","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Join","truth_index":null},"role":"Science & Research","role_family":"Science & Research","seniority":"senior","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Wädenswil, Switzerland"],"countries":["CH"],"hiring_countries":[],"hiring_countries_total":0,"salary":null,"salary_estimate":{"min_usd":82000,"max_usd":186000,"period":"year","method":"global_role_cell_scaled_by_country","sample_n":1296},"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"Bioreactors","optional":false},{"name":"Cell Culture","optional":true}],"status":"live","first_seen_at":"2026-03-24T09:38:50Z","employer_posted_date":"2026-03-24","last_verified_at":"2026-10-29T11:19:15Z","board_verified":true,"closed_at":null,"days_open":219,"trust":{"level":"stale","repost_count":0,"flags":["stale"],"days_open":218},"description":"The Senior Scientist, Upstream Process Development will play a hands-on role in advancing our novel expression technology by developing, optimizing, and scaling fermentation and cell-culture processes.\nThis role is for a senior upstream scientist who will help push our novel expression technology to the next level by developing, challenging, and improving fermentation and cell-culture processes through deep scientific thinking, creativity, and hands-on experimentation.\nWe are looking for an experienced, creative, and persistent upstream Senior Scientist who actively uses literature, engineering judgment, and hands-on experimentation to solve complex bioprocess challenges.\nTasks\nUpstream Process Development\nDesign and execute upstream process-development studies with minimal supervision.\nTranslate literature insights into hypothesis-driven experiments and process improvements.\nIdentify and optimize critical process parameters affecting upstream performance.\nApply analytical tools to improve understanding of organism physiology and fermentation performance.\nRun bioreactors regularly as part of the development workflow and support routine production when needed.\nDocument, analyze, and present experimental data clearly.\nPerform core laboratory activities, including media preparation, shake-flask studies, bioreactor setup and operation, process monitoring, inoculation, harvest, centrifugation, and sterile filtration.\nFollow SOPs and guidelines to maintain culture integrity, prevent contamination, and ensure compliance.\nInnovation & Problem Solving\nApply creative, engineering-driven thinking to improve the expression platform.\nTroubleshoot bottlenecks and propose innovative, scientifically grounded solutions.\nCross-Functional Collaboration\nCollaborate with process development, analytical development, and protein sciences teams.\nContribute to project planning, timelines, and risk assessments.\nRequirements\nPhD in Biotechnology, Biochemical Engineering, Microbiology, or related field.\nAt least 5 years of relevant experience in fermentation or cell-culture process development. 3 years industry experience.\nStrong hands-on expertise with bioreactors, fermentation control systems, and scale-up principles.\nExperience with contamination-control strategies, operational risk assessment, and process monitoring.\nSolid understanding of bioprocess engineering fundamentals, metabolic principles, and cell physiology.\nExperience with tech transfer activities is a plus.\nBroad hands-on experience with mammalian cell culture platforms, including fed-batch and/or perfusion.\nExperience with microbial expression systems is a plus.\nIndependent, proactive, and able to drive progress with minimal supervision.\nWilling to spend a considerable amount of time hands-on in the laboratory.\nStrong data analysis skills and familiarity with common bioprocess software tools.\nCreative, resourceful, and persistent in solving technical challenges.\nClear communicator and collaborative team player.\nIf this role matches your profile, please upload your CV and motivation 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