{"id":4098828,"url":"https://alion.io/job/guidehouse-staff-scientist-4","title":"Staff Scientist","company":{"id":4179,"name":"Guidehouse","domain":"guidehouse.com","url":"https://alion.io/company/guidehouse","size_band":"5000+","is_staffing_agency":false,"employer_type":"services","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"B","score":80,"open_postings":142,"ghost_share":0.007,"stale_share":0.761,"repost_share":0.028,"time_to_fill_p50_days":29,"computed_at":"2026-11-12T10:38:37Z"}},"role":"Science & Research","role_family":"Science & Research","seniority":"staff","employment_type":"full_time","work_mode":"on_site","remote_scope":null,"remote_scope_basis":null,"remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Bethesda, United States"],"countries":["US"],"hiring_countries":[],"hiring_countries_total":0,"salary":{"min":98000,"max":163000,"currency":"USD","period":"year","gross":null,"usd_annual":163000},"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[],"status":"live","first_seen_at":"2026-11-11T21:22:05Z","employer_posted_date":"2026-11-11","last_verified_at":"2026-11-13T21:40:50Z","board_verified":true,"closed_at":null,"days_open":2,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":2},"description":"Job Family:\nScientistTravel Required:\nNone Clearance Required:\nAbility to Obtain Public TrustWe are currently searching for a Staff Scientist to provide senior-level bench expertise and scientific leadership, while remaining responsive to related laboratory needs and evolving programmatic priorities within the National Institutes of Health (NIH). This is a full-time, on-site opportunity in Bethesda, MD.\nWhat You Will Do:\nInvestigate genetic modifiers and biological mechanisms influencing disease severity and clinical outcomes.\nApply cellular biology, molecular biology, immunology, and bioinformatics methods to study red blood cell dysfunction, acute pain, and inflammation.\nIdentify and evaluate biomarkers for monitoring disease processes and treatment response.\nConduct preclinical studies using animal models, primarily mice, to assess disease mechanisms and investigational therapies.\nIntegrate genotype-phenotype analyses with clinical, laboratory, imaging, and diagnostic data to characterize disease manifestations and identify therapeutic targets.\nEvaluate drugs and experimental compounds in preclinical and clinical research to reduce hemoglobin polymerization, improve red blood cell flexibility and flow properties, or increase fetal hemoglobin production.\n What You Will Need:\nPhD or MD, human genetics, molecular biology, biochemistry, immunology or closely related field.\nMinimum FIVE (5) years of post-doc research experience in areas such as translational research, genetics/ genomics, immunology, and/ or molecular biology.\nMultiple first-author publications in peer reviewed journals.\nHands-on experience working with murine models, specifically transgenic mice.\nExperience in hematology, vascular biology, red blood cell health, and/or related fields such as nephrology.\nProficiency in tissue culture, biochemistry and molecular biology assays, gene expression analysis, and/ or processing patient bio-samples.\nExperience with bioinformatics, statistical interpretation, and managing interdisciplinary research projects.\nMust be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.\n What Would Be Nice To Have:\nStrong written and verbal communication, organizational, and time management skills.\nDetail oriented.\nAble to work independently as well as collaboratively as a team member.\nExperience in training, teaching, and mentoring junior research staff, graduate students, and post-doctoral fellows is strongly preferred.\nStrong evidence of independent scientific leadership, publications, collaboration management and related skill sets.\nThe annual salary range for this position is $98,000.00-$163,000.00. Compensation decisions depend on a wide range of factors, including but not limited to skill sets, experience and training, security clearances, licensure and certifications, and other business and organizational needs. What We Offer:\nGuidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.\nBenefits include:\nMedical, Rx, Dental & Vision Insurance\n\nPersonal and Family Sick Time & Company Paid Holidays\n\nParental Leave\n\n401(k) Retirement Plan\n\nGroup Term Life and Travel Assistance\n\nVoluntary Life and AD&D Insurance\n\nHealth Savings Account, Health Care & Dependent Care Flexible Spending Accounts\n\nTransit and Parking Commuter Benefits\n\nShort-Term & Long-Term Disability\n\nTuition Reimbursement, Personal Development, Certifications & Learning Opportunities\n\nEmployee Referral Program\n\nCorporate Sponsored Events & Community Outreach\n\nCare.com annual membership\n\nEmployee Assistance Program\n\nSupplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)\n\nPosition may be eligible for a discretionary variable incentive bonus\n\nAbout Guidehouse\nGuidehouse is an Equal Opportunity Employer-Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.\nGuidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.\nIf you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at . All information you provide will be kept confidential and will be used only to the extent required to provide needed reasonable accommodation.\nAll communication regarding recruitment for a Guidehouse position will be sent from Guidehouse email domains including @guidehouse.com or . Correspondence received by an applicant from any other domain should be considered unauthorized and will not be honored by Guidehouse. Note that Guidehouse will never charge a fee or require a money transfer at any stage of the recruitment process and does not collect fees from educational institutions for participation in a recruitment event. Never provide your banking information to a third party purporting to need that information to proceed in the hiring process.\nIf any person or organization demands money related to a job opportunity with Guidehouse, please report the matter to Guidehouse’s Ethics Hotline. If you want to check the validity of correspondence you have received, please contact . Guidehouse is not responsible for losses incurred (monetary or otherwise) from an applicant’s dealings with unauthorized third parties.\nGuidehouse does not accept unsolicited resumes through or from search firms or staffing agencies. All unsolicited resumes will be considered the property of Guidehouse and Guidehouse will not be obligated to pay a placement fee.","description_format":"text","description_chars":6113,"description_truncated":false,"requirements":{"experience_years_min":5,"management_years_min":null,"team_size_min":null,"manages_managers":false,"education":{"level":"phd","optional":false},"security_clearance":true,"languages":[]},"benefits":["Parental leave","Retirement plans","Vision insurance"],"hiring_locations":[],"hiring_excludes":[],"relocation_offered":false,"industries":["Digital Government","IT Consulting & Digital Transformation","Management Consulting"],"lifecycle":[{"event":"open","at":"2026-11-11T21:22:05Z"}],"visa":[{"country":"US","licensed_sponsor":true,"adverts_offering_sponsorship_24m":0,"sanctioned_now":false,"evidence":"H-1B filings in 12 months: 63 · green card filings: 27","filings_12m":63,"filings_prev_12m":57,"green_card_filings_12m":27,"median_offered_wage_usd":128889,"route":null,"cap_exempt":false,"checked_at":"2026-11-12T07:36:15+00:00","sources":["US Department of Labor: LCA disclosure data (H-1B, H-1B1, E-3)","US Department of Labor: PERM disclosure data (green cards)"],"filings_for_role_12m":0}],"liveness":{"score":63,"band":"ok","label":"Likely open","p_open":1,"p_active":0.632,"p_room":1,"age_days":0,"expected_fill_days":29,"reasons":["conf:0","stale_co","velocity","win:early","comp:brand"],"computed_at":"2026-11-12T10:38:37Z"},"pay":{"stated_usd_annual":163000,"is_top_pay":false},"html_url":"https://alion.io/job/guidehouse-staff-scientist-4","json_url":"https://alion.io/job/guidehouse-staff-scientist-4.json","meta":{"generated_at":"2026-11-14T00:20:16Z","cache_seconds":300,"methodology":"https://alion.io/methodology","terms":"https://alion.io/terms","contact":"https://alion.io/contact","api":"https://alion.io/developers","about":"Alion is a live layer of people, companies and AI agents: who they are, whether they are real and active right now, what they do and how to work with them, readable by people and by agents and paid per call.","catalog":"https://alion.io/catalog.json","usage":{"tier":"crawler_verified","counted_by":"address","units_charged":1,"used_today":724,"day_limit":null,"remaining_today":null,"minute_limit":300,"resets_at":"2026-11-15T00:00:00Z"}},"offers":[{"id":"company.slices","title":"One company in depth, by slice","status":"live","price":{"credits":0.1,"usd":0.01,"plus_per_slice":{"credits":0.05,"usd":0.005}},"unit":"per company, plus each slice with data","note":"the employer in depth","call":{"mcp_tool":"get_company","arguments":{"id":4179},"rest":"https://alion.io/mcp/rest/get_company?id=4179"},"human":"https://alion.io/catalog?offer=company.slices&for=job%2Fguidehouse-staff-scientist-4"},{"id":"market.stats","title":"A market slice: pay, demand and time to fill","status":"free","price":{"credits":0,"usd":0},"unit":"per slice","note":"pay, demand and time to fill for this role and place","call":{"mcp_tool":"market_stats"},"human":"https://alion.io/catalog?offer=market.stats&for=job%2Fguidehouse-staff-scientist-4"},{"id":"job.search","title":"Open jobs by role, technology, place, pay and visa","status":"live","price":{"credits":0.1,"usd":0.01},"unit":"per posting in a list","note":"similar open postings","call":{"mcp_tool":"search_jobs"},"human":"https://alion.io/catalog?offer=job.search&for=job%2Fguidehouse-staff-scientist-4"},{"id":"company.verify","title":"Is this company real and active right now","status":"pilot","price":null,"unit":"per company","request":{"url":"https://alion.io/catalog/request","method":"POST","body":"{\"offer\": \"company.verify\", \"for\": \"job/guidehouse-staff-scientist-4\", \"note\": \"what you need it for\"}"},"human":"https://alion.io/catalog?offer=company.verify&for=job%2Fguidehouse-staff-scientist-4"}],"agent":{"mcp":"https://alion.io/mcp/jobs","mcp_open":"https://alion.io/mcp/open","next":[{"tool":"get_job","arguments":{"id":4098828}},{"tool":"search_jobs","arguments":{"company":"guidehouse.com","detail":"compact"}},{"tool":"match_people","arguments":{"job_id":4098828},"note":"people open to offers who fit this vacancy"}],"note":"The same data through MCP tools: https://alion.io/mcp/open needs no sign-in (compact searches, postings, people); https://alion.io/mcp with an Alion account has everything. Docs: https://alion.io/developers"}}