{"id":3718498,"url":"https://alion.io/job/icon-senior-clinical-data-science-lead-4","title":"Senior Clinical Data Science Lead","company":{"id":5677,"name":"ICON","domain":"iconplc.com","url":"https://alion.io/company/icon","size_band":"5000+","is_staffing_agency":false,"employer_type":"direct","is_intermediary":false,"listed_via":null,"ats_vendor":"Workday","truth_index":{"grade":"A","score":87,"open_postings":68,"ghost_share":0,"stale_share":0.706,"repost_share":0,"time_to_fill_p50_days":20,"computed_at":"2026-11-15T07:52:55Z"}},"role":"Data Science","role_family":"Data Science","seniority":"lead","employment_type":"full_time","work_mode":"remote","remote_scope":"stated_countries","remote_scope_basis":"board_field","remote_working_hours":null,"hiring_geo_confidence":"structured","locations":["Reading, United Kingdom","Johannesburg, South Africa"],"countries":["GB","ZA"],"hiring_countries":["GB"],"hiring_countries_total":1,"salary":null,"salary_estimate":null,"experience_years_min":5,"visa_sponsorship":false,"relocation_package":false,"has_equity":false,"technologies":[{"name":"GCP","optional":false},{"name":"SAS","optional":false}],"status":"live","first_seen_at":"2026-11-02T00:00:00Z","employer_posted_date":"2026-11-02","last_verified_at":"2026-11-15T05:39:58Z","board_verified":true,"closed_at":null,"days_open":13,"trust":{"level":"ok","repost_count":null,"flags":[],"days_open":13},"description":"Senior Clinical Data Science LeadAt ICON Strategic Solutions, you will work in a sponsor-dedicated model, supported by ICON’s global expertise.\nAs the world’s largest FSP organisation, with over 90 sponsor partnerships, we offer stability, career development and a collaborative environment where your work contributes to the development of treatments that benefit patients worldwide.\nSenior Clinical Data Science Lead - Sponsor Dedicated\nUK or South Africa \nAs a Senior Clinical Data Science Lead at ICON, you will lead the analysis, interpretation, and management of clinical data to drive the success of our clinical trials.\nWhat You Will Do:\nYou will oversee clinical data science workstreams, ensuring deliverables meet quality and timeline expectations.\nWhat You Will Be Doing:\nLeading Clinical Data Management activities across assigned studies, from study start-up through to database closure and clean database declaration.\nProviding oversight and guidance to Data Management staff assigned to specific protocols, including mentoring and training less experienced colleagues.\nActing as an experienced Clinical Data Management resource for global, cross-functional study teams and serving as an escalation point for study-related data management matters.\nDeveloping and maintaining study-specific data management components and specifications, including eCRFs, study metadata, edit checks, Data Validation Documents and protocol deviation documentation.\nCollaborating with EDC developers on the specification and design of eCRFs and database structures and contributing to EDC User Acceptance Testing (UAT).\nManaging data cleaning activities, including identifying and issuing queries, incorporating query responses, tracking query status and performing consistency checks on external data.\nCoordinating SAS programming requirements for edit checks and derivations and contributing to the preparation of data monitoring activities.\nPreparing data listings and extracts to support medical reviews, study reporting and other cross-functional activities.\nDeveloping and coordinating database closure plans and ensuring database closure activities are effectively communicated and delivered across the study team.\nIdentifying and communicating issues that could impact study timelines or data quality and working collaboratively with study teams to address them.\nEnsuring Clinical Data Management activities are appropriately documented throughout the lifecycle of the study.\nSupporting training and education initiatives for Data Management colleagues to promote quality, productivity and consistent working practices.\nYour Profile:\nBachelor’s degree or equivalent in Natural Sciences, Informatics, Medical Documentation, or a related discipline.\n5+ years of experience as a Clinical Data Manager, with significant responsibility within clinical projects and study teams.\nStrong understanding of the drug development process and extensive experience with clinical data management methodologies and technologies.\nProven experience managing clinical data from study start-up through to clean database declaration.\nExperience working within global, cross-functional teams and collaborating with functions such as Study Management, Medical, EDC Development, Statistics and Medical Writing.\nDemonstrated ability to interpret Clinical Study Protocols, Statistical Analysis Plans and Medical Review Plans and translate these into appropriate data management specifications.\nExperience developing specifications including CRFs, metadata, protocol deviation documents and edit check specifications.\nGood understanding of relevant clinical research regulations and guidelines, including ICH and GCP.\nExperience training and/or mentoring junior Data Management colleagues, with the ability to provide guidance and act as an escalation point.\nStrong project management, organisational and self-management skills, with the ability to work independently and effectively manage priorities.\nExperience working within and helping lead global, cross-functional teams towards key study milestones such as First Patient First Visit readiness and timely clean database declaration.\nStrong written and verbal communication skills in English, with fluent spoken English required, alongside strong local-language communication skills.\nGood understanding of IT processes and databases used within Clinical Development.\nA proactive approach to continuous learning and professional development.\nEmployment with ICON is contingent upon having the legal right to work in the country where the role is based.\nRewards & Benefits\nICON offers a competitive and comprehensive total rewards package designed to support your health, wellbeing, and career development.\nBenefits may include:\nCompetitive base salary and performance related incentives\nHealth and wellbeing programmes including medical, dental, and vision coverage where applicable\nRetirement and pension plans\nLife assurance and disability coverage\nEmployee assistance programmes and wellbeing resources\nLearning and development opportunities through structured training and career pathways\nBenefits may vary depending on role and location.\nVisit our careers site to read more about the benefits ICON offers.\nInclusion and Accessibility\nICON is an equal opportunity employer. We are committed to building an inclusive and accessible workplace where everyone feels valued and supported.\nIf you require reasonable accommodations during the recruitment process, please let us know or submit a request here.\nAre you a current ICON Employee? 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